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The map label for this gene is nuoC

Identifier: 119356791

GI number: 119356791

Start: 1103777

End: 1104277

Strand: Direct

Name: nuoC

Synonym: Cpha266_0963

Alternate gene names: 119356791

Gene position: 1103777-1104277 (Clockwise)

Preceding gene: 119356790

Following gene: 119356792

Centisome position: 35.22

GC content: 50.1

Gene sequence:

>501_bases
ATGACACAGCAGGTAAAGCAGGCGCTCGCAGCGTACGACGTTGTCCGCGAGAAATTCGGTGATGCCGTTTCGGCATTTGA
TTCGAATGAGACGATGCCATTTTTCGAGGTTCTCGATACCGATCAGTGGCCTGACATCGCGCTTTTTATGCGTGATCATC
CTAAACTGAAATTCAATTATATGGCTTGCCTTTCAGGGGTTGATTATCCCCAGGAAGAGAAGCTCGGTATTGTCTGCAAT
CTCGAATCTGTTGCCGCTTTAGGGCACAGGGTTGCCGTAAAGGTTCGTTGTTCGCGCGATGGCGGTTCAATACCCTCTGT
TGCCTGTGTCTGGCATACGGCGAACTGGCATGAGCGGGAGGCGTATGATATGTTTGGCATGTTGTTTTCCGGCCACCCTG
ATTTGAGACGGATTCTCTGTCCTGAAGACTGGGAAGGGTTTCCGCTTCGCAAGGATTACAAGGTACAGGAGACCTATCAT
GGAATCAAGGTTCCATACTGA

Upstream 100 bases:

>100_bases
AAGCGTTGACCCCAGAGTTGTTATTGAAGAGGAACGCAAGGCGTTGAGGGCATAACAATAAAGCTTAATACCCGGTATAT
ACATGGAACCAGGTTTGGAA

Downstream 100 bases:

>100_bases
AAGAGTTTAACTTGAATAAAGCAGTTCACGTATGCAGGAATTAGGGATAACTGGACAGGGCTCAGTAAGGGTTACCCGCA
AGGAGGGTAATGTTGTAGTT

Product: NADH (or F420H2) dehydrogenase, subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTQQVKQALAAYDVVREKFGDAVSAFDSNETMPFFEVLDTDQWPDIALFMRDHPKLKFNYMACLSGVDYPQEEKLGIVCN
LESVAALGHRVAVKVRCSRDGGSIPSVACVWHTANWHEREAYDMFGMLFSGHPDLRRILCPEDWEGFPLRKDYKVQETYH
GIKVPY

Sequences:

>Translated_166_residues
MTQQVKQALAAYDVVREKFGDAVSAFDSNETMPFFEVLDTDQWPDIALFMRDHPKLKFNYMACLSGVDYPQEEKLGIVCN
LESVAALGHRVAVKVRCSRDGGSIPSVACVWHTANWHEREAYDMFGMLFSGHPDLRRILCPEDWEGFPLRKDYKVQETYH
GIKVPY
>Mature_165_residues
TQQVKQALAAYDVVREKFGDAVSAFDSNETMPFFEVLDTDQWPDIALFMRDHPKLKFNYMACLSGVDYPQEEKLGIVCNL
ESVAALGHRVAVKVRCSRDGGSIPSVACVWHTANWHEREAYDMFGMLFSGHPDLRRILCPEDWEGFPLRKDYKVQETYHG
IKVPY

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=109, Percent_Identity=41.2844036697248, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693162, Length=68, Percent_Identity=44.1176470588235, Blast_Score=77, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71990788, Length=107, Percent_Identity=38.3177570093458, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563621, Length=107, Percent_Identity=38.3177570093458, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656494, Length=109, Percent_Identity=37.6146788990826, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_CHLPD (A1BF34)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911435.1
- STRING:   A1BF34
- GeneID:   4570732
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0963
- NMPDR:   fig|290317.7.peg.1025
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   KFNYMAC
- ProtClustDB:   CLSK637460
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 19038; Mature: 18907

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQVKQALAAYDVVREKFGDAVSAFDSNETMPFFEVLDTDQWPDIALFMRDHPKLKFNY
CCHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHCCCCCCCEEEEECCCCCEEEHH
MACLSGVDYPQEEKLGIVCNLESVAALGHRVAVKVRCSRDGGSIPSVACVWHTANWHERE
HHHHCCCCCCCCCCEEEEECHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCHH
AYDMFGMLFSGHPDLRRILCPEDWEGFPLRKDYKVQETYHGIKVPY
HHHHHHHHHCCCCCHHEEECCCCCCCCCCCCCCCHHHHHCCEECCC
>Mature Secondary Structure 
TQQVKQALAAYDVVREKFGDAVSAFDSNETMPFFEVLDTDQWPDIALFMRDHPKLKFNY
CHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHCCCCCCCEEEEECCCCCEEEHH
MACLSGVDYPQEEKLGIVCNLESVAALGHRVAVKVRCSRDGGSIPSVACVWHTANWHERE
HHHHCCCCCCCCCCEEEEECHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCHH
AYDMFGMLFSGHPDLRRILCPEDWEGFPLRKDYKVQETYHGIKVPY
HHHHHHHHHCCCCCHHEEECCCCCCCCCCCCCCCHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA