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The map label for this gene is fabI1 [H]

Identifier: 119356514

GI number: 119356514

Start: 775225

End: 776106

Strand: Direct

Name: fabI1 [H]

Synonym: Cpha266_0679

Alternate gene names: 119356514

Gene position: 775225-776106 (Clockwise)

Preceding gene: 119356513

Following gene: 119356515

Centisome position: 24.74

GC content: 46.26

Gene sequence:

>882_bases
ATGCCCGAGAAAGCGCACTACGGTCTTTTAAAAGGAAAAAAAGGAATTGTTTTCGGTCCTCTTGATGAAAGCAGTATCGG
ATGGCAGATTGCACTTCATGCCTATCGGGAGGGTGCCGAGATTGCAATATCGAATGTCGCTACCGCTCTGCGTTTTGGCA
ATATTGAGGAACTTGCTCTTCTTTGCGGCAATGCTCCTGTTATTGTGTGCGATGCATCAAGAAACGAGGATGTTGATAAT
TGTTTCAAAGAGTTGAAGGAGAAGATGGGGGCTGTCGATTTTATCGTTCACTCCATTGGCATGTCGCAGAACATCCGTAA
GCAGCTTCCTTACGAGGAGTTGAACTATGAATGGTTCATGAGGACGCTTGATGTTTCCGGTCTTTCGTTGCACAGGATTG
TTTCCTATGCTCTTAAAAACGATGCGATCAACGCTGGAGGAAGCATTGTTGCGCTATCCTATATAGCATCACAACGGAAT
TACTGGACCTATTCCGATATGGGAGATGCCAAATCCCTTCTCGAATCGATTGCCAGAAGCTATGGTCCGAGGCTTGCAAA
GCGGGCTATACGTATCAATACGGTTTCTCAAAGCCCAACCTATACGAAAGCAGGCAGCGGTATTCCGGGATTTGAGAAAA
TGTACGAATACAGTGATCTCATGTCACCGCTTGGTAATGCATCTGCCGAAGAGTGTGCAGAATATACGATGACTTTGCTC
AGCGATCTTTCACGAAAGGTCACCATGCAGAATCTCTTTCATGATGGTGGGTACAGTTCGATGGGCGCAACCATTCCCAT
GATTAAGCTTGCTCATGAAGTGCTTAACGACAGGGAACTTGCCGCAAGAGTCGGACTTGATGATGTTTCGCCTTCAACGT
GA

Upstream 100 bases:

>100_bases
GTTTAAGTTTTCAGGGGAATCTTGTATCTTCTTTATTTTAAATATTCACATTAACGGGAGTTTTCGTTCCGTTCTTTGTT
AAAGAATCACAGCTTATATC

Downstream 100 bases:

>100_bases
GTTATTGACGAAAGAAGCCCGGACATTTTTATCTCAGCGTTTAATAGCTACCAGGGTTGCAATGAACATCGTCGTGAGTT
TCTGTTAAAACGGAATACAT

Product: enoyl-[acyl-carrier-protein] reductase [NADH]

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase 1 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPEKAHYGLLKGKKGIVFGPLDESSIGWQIALHAYREGAEIAISNVATALRFGNIEELALLCGNAPVIVCDASRNEDVDN
CFKELKEKMGAVDFIVHSIGMSQNIRKQLPYEELNYEWFMRTLDVSGLSLHRIVSYALKNDAINAGGSIVALSYIASQRN
YWTYSDMGDAKSLLESIARSYGPRLAKRAIRINTVSQSPTYTKAGSGIPGFEKMYEYSDLMSPLGNASAEECAEYTMTLL
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDRELAARVGLDDVSPST

Sequences:

>Translated_293_residues
MPEKAHYGLLKGKKGIVFGPLDESSIGWQIALHAYREGAEIAISNVATALRFGNIEELALLCGNAPVIVCDASRNEDVDN
CFKELKEKMGAVDFIVHSIGMSQNIRKQLPYEELNYEWFMRTLDVSGLSLHRIVSYALKNDAINAGGSIVALSYIASQRN
YWTYSDMGDAKSLLESIARSYGPRLAKRAIRINTVSQSPTYTKAGSGIPGFEKMYEYSDLMSPLGNASAEECAEYTMTLL
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDRELAARVGLDDVSPST
>Mature_292_residues
PEKAHYGLLKGKKGIVFGPLDESSIGWQIALHAYREGAEIAISNVATALRFGNIEELALLCGNAPVIVCDASRNEDVDNC
FKELKEKMGAVDFIVHSIGMSQNIRKQLPYEELNYEWFMRTLDVSGLSLHRIVSYALKNDAINAGGSIVALSYIASQRNY
WTYSDMGDAKSLLESIARSYGPRLAKRAIRINTVSQSPTYTKAGSGIPGFEKMYEYSDLMSPLGNASAEECAEYTMTLLS
DLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDRELAARVGLDDVSPST

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=260, Percent_Identity=30.7692307692308, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 32210; Mature: 32079

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEKAHYGLLKGKKGIVFGPLDESSIGWQIALHAYREGAEIAISNVATALRFGNIEELAL
CCCCCCCCHHCCCCCCEECCCCCCCCCHHEEHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
LCGNAPVIVCDASRNEDVDNCFKELKEKMGAVDFIVHSIGMSQNIRKQLPYEELNYEWFM
HHCCCCEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHCCHHHCCHHHHH
RTLDVSGLSLHRIVSYALKNDAINAGGSIVALSYIASQRNYWTYSDMGDAKSLLESIARS
HHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHH
YGPRLAKRAIRINTVSQSPTYTKAGSGIPGFEKMYEYSDLMSPLGNASAEECAEYTMTLL
HCHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDRELAARVGLDDVSPST
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PEKAHYGLLKGKKGIVFGPLDESSIGWQIALHAYREGAEIAISNVATALRFGNIEELAL
CCCCCCCHHCCCCCCEECCCCCCCCCHHEEHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
LCGNAPVIVCDASRNEDVDNCFKELKEKMGAVDFIVHSIGMSQNIRKQLPYEELNYEWFM
HHCCCCEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHCCHHHCCHHHHH
RTLDVSGLSLHRIVSYALKNDAINAGGSIVALSYIASQRNYWTYSDMGDAKSLLESIARS
HHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHH
YGPRLAKRAIRINTVSQSPTYTKAGSGIPGFEKMYEYSDLMSPLGNASAEECAEYTMTLL
HCHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SDLSRKVTMQNLFHDGGYSSMGATIPMIKLAHEVLNDRELAARVGLDDVSPST
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]