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The map label for this gene is 119356513

Identifier: 119356513

GI number: 119356513

Start: 773777

End: 775078

Strand: Direct

Name: 119356513

Synonym: Cpha266_0678

Alternate gene names: NA

Gene position: 773777-775078 (Clockwise)

Preceding gene: 119356512

Following gene: 119356514

Centisome position: 24.69

GC content: 45.01

Gene sequence:

>1302_bases
ATGTTATCGAGGGACTTAACGGAAAATCAGTCTCAGCCGAGAGTTATCATTTATTCCGGAAAGGGCGGAACGGGAAAAAC
CACGATATCTTCGTCAACAGCCGTAGCGCTTGCAAGGCAGAACAAGAAAGTGCTTATCATGTCGTCCGATCCGGCACACT
CCTTGTCGGATGTCTTTGATACGCAAATAAGTCGTAATGATCCGCAGAGAATTGAGAAAAATCTTTACGGGCTCGAAATT
GACACGATATACGAGCTGAAAAAAAACATGTCGGGGTTCCAGAAATTTGTCTCTTCTTCCTATAAAAACCAGGGGATTGA
CAGCGGCATGGCCTCTGAATTGACAACGCAGCCTGGTCTTGACGAGATTTTTGCTCTGAATCGTCTGGTTGATGAAGCCC
AGTCCGGAAAATGGGATGCCGTGGTGCTCGATACTTCCCCGACAGGCAATACCCTTCGCCTGCTTGCCTATCCTGAAATT
ATTATTGGCGGCAATATGGGCAAGCAGTTTTTCAAGTTGTACAAAAGCATGTCATCTCTTGCCCGTCCACTGAGTGGTAA
CTCGATTCCTGATGGAGAGTTTTTTAACGAGGTCAATGTACTGCTCAAGCAGATGGAGGATATCAACAAATTTATTCTCA
GTCCTGAGGTTACCTTCCGTCTGGTATTGAATCCTGAGAAACTGTCGATTCTTGAGACGAAACGAGCATATACCTTTATC
CATCTGTATGGGATCAATATTGATGCTATTGTTATTAACAAGATTCTTCCTACTTCGAAGACCGTAGGTGAGTATTTTGA
GTTCTGGGCTGATCTGCATACCAAGTATCTGATGGAGATTGATAACTCTTTTTATCCGACGCCTGTATTTCGATGCAATC
TTCAGCGGACCGAGCCTATCGGATCCGATGCACTTCATGAGATCAGCAAACTGGTGTTTGGAGAGCAGATTCCCGACAAG
ACCTTCTATGAAGGGAAAAATTTCTGGATCGAGAGCCGTAAAAATGCCGTCACCGAAGATCATCGTGAGATTCTTTGCAT
CAGGATTCCCTTTCTCAAGGATGCCGAAGATGTGAAGGTCGAGCGAATGGGAACCGATATTGTGGTAACCGTTGATCGGG
CACAGCGGATAATTACCCTTCCAAGAGCGCTGTACAGTCTGGATCTGGAAGAGTATCTTATCGAGGATAACCTTCTTCGC
GTAGTATTCAAGGAGACTCCTGTCGAAAAGGATGAGGTGGAGTTGAGCGTCAACAAAAATATGCTTGACAAGCTTCGTTC
TATGAGAAGGATGAAGATTTAG

Upstream 100 bases:

>100_bases
TTGCACTCGGCAAAAAGATTCGTTTCATCTAAGGCGGGAAAATGGTACCTTATAAGCTATTATGTTTTGTGATCTATGAC
CTTTAACAGTGGAGATGTTT

Downstream 100 bases:

>100_bases
GCATTGTTTCGCTAAAAGCTTCAGAGTGAAAATTTCTGAGGAAACTGTTTAAGTTTTCAGGGGAATCTTGTATCTTCTTT
ATTTTAAATATTCACATTAA

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLSRDLTENQSQPRVIIYSGKGGTGKTTISSSTAVALARQNKKVLIMSSDPAHSLSDVFDTQISRNDPQRIEKNLYGLEI
DTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALNRLVDEAQSGKWDAVVLDTSPTGNTLRLLAYPEI
IIGGNMGKQFFKLYKSMSSLARPLSGNSIPDGEFFNEVNVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTFI
HLYGINIDAIVINKILPTSKTVGEYFEFWADLHTKYLMEIDNSFYPTPVFRCNLQRTEPIGSDALHEISKLVFGEQIPDK
TFYEGKNFWIESRKNAVTEDHREILCIRIPFLKDAEDVKVERMGTDIVVTVDRAQRIITLPRALYSLDLEEYLIEDNLLR
VVFKETPVEKDEVELSVNKNMLDKLRSMRRMKI

Sequences:

>Translated_433_residues
MLSRDLTENQSQPRVIIYSGKGGTGKTTISSSTAVALARQNKKVLIMSSDPAHSLSDVFDTQISRNDPQRIEKNLYGLEI
DTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALNRLVDEAQSGKWDAVVLDTSPTGNTLRLLAYPEI
IIGGNMGKQFFKLYKSMSSLARPLSGNSIPDGEFFNEVNVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTFI
HLYGINIDAIVINKILPTSKTVGEYFEFWADLHTKYLMEIDNSFYPTPVFRCNLQRTEPIGSDALHEISKLVFGEQIPDK
TFYEGKNFWIESRKNAVTEDHREILCIRIPFLKDAEDVKVERMGTDIVVTVDRAQRIITLPRALYSLDLEEYLIEDNLLR
VVFKETPVEKDEVELSVNKNMLDKLRSMRRMKI
>Mature_433_residues
MLSRDLTENQSQPRVIIYSGKGGTGKTTISSSTAVALARQNKKVLIMSSDPAHSLSDVFDTQISRNDPQRIEKNLYGLEI
DTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGLDEIFALNRLVDEAQSGKWDAVVLDTSPTGNTLRLLAYPEI
IIGGNMGKQFFKLYKSMSSLARPLSGNSIPDGEFFNEVNVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTFI
HLYGINIDAIVINKILPTSKTVGEYFEFWADLHTKYLMEIDNSFYPTPVFRCNLQRTEPIGSDALHEISKLVFGEQIPDK
TFYEGKNFWIESRKNAVTEDHREILCIRIPFLKDAEDVKVERMGTDIVVTVDRAQRIITLPRALYSLDLEEYLIEDNLLR
VVFKETPVEKDEVELSVNKNMLDKLRSMRRMKI

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=295, Percent_Identity=26.1016949152542, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17557003, Length=306, Percent_Identity=26.1437908496732, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320103, Length=322, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586297, Length=239, Percent_Identity=27.6150627615063, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 49338; Mature: 49338

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRDLTENQSQPRVIIYSGKGGTGKTTISSSTAVALARQNKKVLIMSSDPAHSLSDVFD
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHHHHHH
TQISRNDPQRIEKNLYGLEIDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGL
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCH
DEIFALNRLVDEAQSGKWDAVVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSMSSL
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHH
ARPLSGNSIPDGEFFNEVNVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTFI
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHEECCCEEEEE
HLYGINIDAIVINKILPTSKTVGEYFEFWADLHTKYLMEIDNSFYPTPVFRCNLQRTEPI
EEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
GSDALHEISKLVFGEQIPDKTFYEGKNFWIESRKNAVTEDHREILCIRIPFLKDAEDVKV
CHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCC
ERMGTDIVVTVDRAQRIITLPRALYSLDLEEYLIEDNLLRVVFKETPVEKDEVELSVNKN
EECCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHEEEHHCCCCCCCCEEEEECHH
MLDKLRSMRRMKI
HHHHHHHHHHCCC
>Mature Secondary Structure
MLSRDLTENQSQPRVIIYSGKGGTGKTTISSSTAVALARQNKKVLIMSSDPAHSLSDVFD
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCEEEEEECCCEEEEEECCCCHHHHHHHH
TQISRNDPQRIEKNLYGLEIDTIYELKKNMSGFQKFVSSSYKNQGIDSGMASELTTQPGL
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCH
DEIFALNRLVDEAQSGKWDAVVLDTSPTGNTLRLLAYPEIIIGGNMGKQFFKLYKSMSSL
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHH
ARPLSGNSIPDGEFFNEVNVLLKQMEDINKFILSPEVTFRLVLNPEKLSILETKRAYTFI
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHEECCCEEEEE
HLYGINIDAIVINKILPTSKTVGEYFEFWADLHTKYLMEIDNSFYPTPVFRCNLQRTEPI
EEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
GSDALHEISKLVFGEQIPDKTFYEGKNFWIESRKNAVTEDHREILCIRIPFLKDAEDVKV
CHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCC
ERMGTDIVVTVDRAQRIITLPRALYSLDLEEYLIEDNLLRVVFKETPVEKDEVELSVNKN
EECCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHEEEHHCCCCCCCCEEEEECHH
MLDKLRSMRRMKI
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]