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The map label for this gene is ruvC

Identifier: 119356376

GI number: 119356376

Start: 593770

End: 594333

Strand: Direct

Name: ruvC

Synonym: Cpha266_0539

Alternate gene names: 119356376

Gene position: 593770-594333 (Clockwise)

Preceding gene: 119356375

Following gene: 119356377

Centisome position: 18.95

GC content: 50.53

Gene sequence:

>564_bases
ATGGTTGTGCTTGGGGTTGATCCGGGAAGCCTGAAAACCGGCTATGGAGTTGTGAGACAGGACAGTTCAGGATTTTCAGT
GCTGACCTGCGGCGTAATCCGTCTTCATTCCGGAAAAAGTCATGCGGAGCGAATTGGTCAGATTTATCGTGAACTTGAAG
AGATAATTAACTCTACCAAGCCCCGGAGGGTTGCTCTGGAAACGGTTTTTCTCAGTAAAAATGCGCAATCAGCTCTGAAA
CTTGGACAGGTACGCGGTGCGGTCATTGCCCTTTCGATGAACACTGATCTTGAGTTGCACGAATATGCGCCTCGTGAAGT
GAAGTCGGCGGTCACCGGCAGGGGATCAGCAAGCAAAGAACAGGTGGCATTTATGGTTACGCGTATGTTGCAGGTCACCG
GCCACATAACATCTTATGATGTTACCGATGCCTTAGGCCTTGCCTTGTGTGATCTGTTGCGAATAGGGAACCGGGCTGCA
CAGGAGCCAGCTCAAGGCATATCGCGTGGAAACAAGAACTGGACGGGTTTTGTTCGCGCCTTTCCGGAAATGGTTGTCAG
ATAG

Upstream 100 bases:

>100_bases
CAGGATTATTGATGCCCTTGAAAATAACGATGATGTTCAGGCCGTATACAGTAACATGGAGATCAGCGAAAAAGCCATGA
ACAGTTTAAATGAGTAGCTA

Downstream 100 bases:

>100_bases
TTTCATAAAAAGAGGCCGGAAGGGGGTTCATTGCTTTCAGGTCTTGTCGGGCGGATGGAATCGGAACAGTGTTACTCTAC
GAATTAATCTTTATACATTG

Product: crossover junction endodeoxyribonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MVVLGVDPGSLKTGYGVVRQDSSGFSVLTCGVIRLHSGKSHAERIGQIYRELEEIINSTKPRRVALETVFLSKNAQSALK
LGQVRGAVIALSMNTDLELHEYAPREVKSAVTGRGSASKEQVAFMVTRMLQVTGHITSYDVTDALGLALCDLLRIGNRAA
QEPAQGISRGNKNWTGFVRAFPEMVVR

Sequences:

>Translated_187_residues
MVVLGVDPGSLKTGYGVVRQDSSGFSVLTCGVIRLHSGKSHAERIGQIYRELEEIINSTKPRRVALETVFLSKNAQSALK
LGQVRGAVIALSMNTDLELHEYAPREVKSAVTGRGSASKEQVAFMVTRMLQVTGHITSYDVTDALGLALCDLLRIGNRAA
QEPAQGISRGNKNWTGFVRAFPEMVVR
>Mature_187_residues
MVVLGVDPGSLKTGYGVVRQDSSGFSVLTCGVIRLHSGKSHAERIGQIYRELEEIINSTKPRRVALETVFLSKNAQSALK
LGQVRGAVIALSMNTDLELHEYAPREVKSAVTGRGSASKEQVAFMVTRMLQVTGHITSYDVTDALGLALCDLLRIGNRAA
QEPAQGISRGNKNWTGFVRAFPEMVVR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=134, Percent_Identity=45.5223880597015, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_CHLPD (A1BDW9)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911020.1
- ProteinModelPortal:   A1BDW9
- SMR:   A1BDW9
- STRING:   A1BDW9
- GeneID:   4569076
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_0539
- NMPDR:   fig|290317.7.peg.563
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   CLSK637877
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 20299; Mature: 20299

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLGVDPGSLKTGYGVVRQDSSGFSVLTCGVIRLHSGKSHAERIGQIYRELEEIINSTK
CEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
PRRVALETVFLSKNAQSALKLGQVRGAVIALSMNTDLELHEYAPREVKSAVTGRGSASKE
CCHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCCCHHHCCCHHHHHHHCCCCCCCHH
QVAFMVTRMLQVTGHITSYDVTDALGLALCDLLRIGNRAAQEPAQGISRGNKNWTGFVRA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCCCHHHHHHH
FPEMVVR
HHHHHCC
>Mature Secondary Structure
MVVLGVDPGSLKTGYGVVRQDSSGFSVLTCGVIRLHSGKSHAERIGQIYRELEEIINSTK
CEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
PRRVALETVFLSKNAQSALKLGQVRGAVIALSMNTDLELHEYAPREVKSAVTGRGSASKE
CCHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCCCHHHCCCHHHHHHHCCCCCCCHH
QVAFMVTRMLQVTGHITSYDVTDALGLALCDLLRIGNRAAQEPAQGISRGNKNWTGFVRA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHCCCCCHHHHHHH
FPEMVVR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA