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The map label for this gene is btuB [H]

Identifier: 119356282

GI number: 119356282

Start: 490938

End: 492941

Strand: Direct

Name: btuB [H]

Synonym: Cpha266_0444

Alternate gene names: 119356282

Gene position: 490938-492941 (Clockwise)

Preceding gene: 119356281

Following gene: 119356283

Centisome position: 15.67

GC content: 48.75

Gene sequence:

>2004_bases
ATGAAAAAAATAGTACTTCTCGTATTGCTTCTTGCTGCCACTGAAACGGTTTTTGCAGCGGAACTTCCATCCGATCTCCC
GGTATCAGGGATAAAAGTGTTTACTGCCGGTGAGGTAACGGTCAGCGGGAAAAAAGACCATGCGAAGGAAACGGTTGCCG
CAACCGAAATGGAGATGCTCGACAAAAAAAATATTGCGCAGGCGGTCAATATGCTTCCCGGCATCAATGTGAGTAATGTT
GGCGGAAGAAATGAGGGGATGGTCTATGTCCGGGGTTTTGACATGCGTCAGGTTCCGCTCTATCTTGACGGTATTCCTCT
CTATGTTCCCTATGACGGCTATATCGATCCAAACCGGTTTACGACGTTTGATCTGTCGGAGATCAACGTTTCAAAGGGTT
TCACTTCGGTACTCTATGGTCCGAATACCCTTGGAGGAGCGATTAACATGGTAAGTCGAAAACCGGCAGAGAGGTTTGAA
GGCAGCTTGAAGGGCGGCCTCACGTTCAGCGATGAAGGATTGGCGTCGGAATTTGCCTCACTCAATCTTGGCAGCAACCA
GGGAACATGGTATGTCCAGGGAAGTCTCTCGATTCTTGATCGTGATTTCATGCAGCTTTCAGATTCCTTTCTTGCAACGA
AAAGTGAAGATGGCAGCAAGCGAGATAATTCGGATTCGCGAGATTTCAGGGGCTCTTTGAAAGTCGGATATACGCCGAAC
TCGACCGATGAGTATTCGCTGAGCATCATATCACAACAGTCAAGCAAGGGTGTACCGGTCTATACAGGCATTAACCCGAC
GCAAACGGTGCGCTACTGGAGGTATGGCGACTGGGACAAATCGAGCATCTACTTTATCGGCAAAAAAGCCCTTGGCAGCA
AAAGCTATCTCAAGGCAAGGGCTTATTATGACAACTATTATAATACCCTGCAGAGCTATGACGACGCTTCCTACGCCACG
CAAAAGACCAAAAAAGCGTTTTCAAGCCGTTATGATGATAAAACCTTTGGCGGTTCCATCGAGTTTGGTACGGAAATCCT
GAGCGGAAATACCTTGAAAATCGCTCTGCATGACAAGTATGACATGCACAATGAAATTGGTAATACCGGCGAGATGCCGA
AAGAGTTTGAAGACAATACCGTTTCAGTAGCCGCTGAAAATACCTGGAAGGCTTCAGACAATATCTCGGTTATAGCGGGT
GTTCGCCAGGATTTTCGGCATACCATCAAGGCAGAGGATCTTGTTGGCGGCGTCATCACCTCCTTTCCGCTTGAGGATAA
CCAGGCGACAAATCTTCAGCTTGCCGTTGTCGGACGTCTCAGCGAGAGTCAGGAGCTGACGGCATACCTTACCAGAACGA
CACGGTTTCCTACATTGAAAGATCGATACTCATACCGCCTGGGCAATGCTTTTCCGAATCCGGAGCTCAAGCCGGAGCAG
AGCCTCAACTATGGGCTTGATTATGCCATAAGACCGGCAGATCAACTCAAATTTCAGGCTTCAGTGTACCAGAGCAAGCT
CAGTGATGTGATCCAGCAGGTGAACAATATCGCTTATGTGAAGGGGATATGGGTCTATCAATTTCAGAATACAGGGGAGG
CGACCTTTACCGGATTCGAGTGCTCCGTTGACTGGCAACCGGTTTCATGGCTGAGGGCTTATAGCGGTTACAGCTATATC
GACCGAAAAAATGACAGCAACCCTTCTCTGCGTTTTACCGATATACCCAGGCACAAGTTCACCGGGTATTTGCAGTTCCT
CTTTAACAAGGATCGTTGGGCGATCGTCGAATCCGAATACTATTCCAGGCGGTACAGCACCAGCGATGGCAAGTATACTG
CCGGAGCCTACGGTCTGATAAATCTCAGGGCCAGCACTGTTCTTTACGATACGCTTTCGCTTCAGGCATCCGTTGAAAAT
GTTTTTGACCGGAACTACGAAGTAGCAGAGGGCTATCCGGAGGCGGGTCGTCAGTATGTGGTGTCGCTTGCCTGGGCGCT
TTGA

Upstream 100 bases:

>100_bases
TGAGTGCATGTTCGTGAAGATGTTATAAAACTGATAACAAGGGTGCTTTTTAATCATCGTTATATTTATTCGGATATAAC
GATTTCCAAACGAAAACTGT

Downstream 100 bases:

>100_bases
TGAACCACCGTAAAGGGAGGAATGCGGAATGAAAGCAACTTGCTGGCAGGCGGATGGCTTGCGGTATCAATAACAGGAAA
AGAGGGGGGTCATGAGCGCA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MKKIVLLVLLLAATETVFAAELPSDLPVSGIKVFTAGEVTVSGKKDHAKETVAATEMEMLDKKNIAQAVNMLPGINVSNV
GGRNEGMVYVRGFDMRQVPLYLDGIPLYVPYDGYIDPNRFTTFDLSEINVSKGFTSVLYGPNTLGGAINMVSRKPAERFE
GSLKGGLTFSDEGLASEFASLNLGSNQGTWYVQGSLSILDRDFMQLSDSFLATKSEDGSKRDNSDSRDFRGSLKVGYTPN
STDEYSLSIISQQSSKGVPVYTGINPTQTVRYWRYGDWDKSSIYFIGKKALGSKSYLKARAYYDNYYNTLQSYDDASYAT
QKTKKAFSSRYDDKTFGGSIEFGTEILSGNTLKIALHDKYDMHNEIGNTGEMPKEFEDNTVSVAAENTWKASDNISVIAG
VRQDFRHTIKAEDLVGGVITSFPLEDNQATNLQLAVVGRLSESQELTAYLTRTTRFPTLKDRYSYRLGNAFPNPELKPEQ
SLNYGLDYAIRPADQLKFQASVYQSKLSDVIQQVNNIAYVKGIWVYQFQNTGEATFTGFECSVDWQPVSWLRAYSGYSYI
DRKNDSNPSLRFTDIPRHKFTGYLQFLFNKDRWAIVESEYYSRRYSTSDGKYTAGAYGLINLRASTVLYDTLSLQASVEN
VFDRNYEVAEGYPEAGRQYVVSLAWAL

Sequences:

>Translated_667_residues
MKKIVLLVLLLAATETVFAAELPSDLPVSGIKVFTAGEVTVSGKKDHAKETVAATEMEMLDKKNIAQAVNMLPGINVSNV
GGRNEGMVYVRGFDMRQVPLYLDGIPLYVPYDGYIDPNRFTTFDLSEINVSKGFTSVLYGPNTLGGAINMVSRKPAERFE
GSLKGGLTFSDEGLASEFASLNLGSNQGTWYVQGSLSILDRDFMQLSDSFLATKSEDGSKRDNSDSRDFRGSLKVGYTPN
STDEYSLSIISQQSSKGVPVYTGINPTQTVRYWRYGDWDKSSIYFIGKKALGSKSYLKARAYYDNYYNTLQSYDDASYAT
QKTKKAFSSRYDDKTFGGSIEFGTEILSGNTLKIALHDKYDMHNEIGNTGEMPKEFEDNTVSVAAENTWKASDNISVIAG
VRQDFRHTIKAEDLVGGVITSFPLEDNQATNLQLAVVGRLSESQELTAYLTRTTRFPTLKDRYSYRLGNAFPNPELKPEQ
SLNYGLDYAIRPADQLKFQASVYQSKLSDVIQQVNNIAYVKGIWVYQFQNTGEATFTGFECSVDWQPVSWLRAYSGYSYI
DRKNDSNPSLRFTDIPRHKFTGYLQFLFNKDRWAIVESEYYSRRYSTSDGKYTAGAYGLINLRASTVLYDTLSLQASVEN
VFDRNYEVAEGYPEAGRQYVVSLAWAL
>Mature_667_residues
MKKIVLLVLLLAATETVFAAELPSDLPVSGIKVFTAGEVTVSGKKDHAKETVAATEMEMLDKKNIAQAVNMLPGINVSNV
GGRNEGMVYVRGFDMRQVPLYLDGIPLYVPYDGYIDPNRFTTFDLSEINVSKGFTSVLYGPNTLGGAINMVSRKPAERFE
GSLKGGLTFSDEGLASEFASLNLGSNQGTWYVQGSLSILDRDFMQLSDSFLATKSEDGSKRDNSDSRDFRGSLKVGYTPN
STDEYSLSIISQQSSKGVPVYTGINPTQTVRYWRYGDWDKSSIYFIGKKALGSKSYLKARAYYDNYYNTLQSYDDASYAT
QKTKKAFSSRYDDKTFGGSIEFGTEILSGNTLKIALHDKYDMHNEIGNTGEMPKEFEDNTVSVAAENTWKASDNISVIAG
VRQDFRHTIKAEDLVGGVITSFPLEDNQATNLQLAVVGRLSESQELTAYLTRTTRFPTLKDRYSYRLGNAFPNPELKPEQ
SLNYGLDYAIRPADQLKFQASVYQSKLSDVIQQVNNIAYVKGIWVYQFQNTGEATFTGFECSVDWQPVSWLRAYSGYSYI
DRKNDSNPSLRFTDIPRHKFTGYLQFLFNKDRWAIVESEYYSRRYSTSDGKYTAGAYGLINLRASTVLYDTLSLQASVEN
VFDRNYEVAEGYPEAGRQYVVSLAWAL

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74656; Mature: 74656

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVLLVLLLAATETVFAAELPSDLPVSGIKVFTAGEVTVSGKKDHAKETVAATEMEML
CHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECEEEECCCCHHHHHHHHHHHHHHH
DKKNIAQAVNMLPGINVSNVGGRNEGMVYVRGFDMRQVPLYLDGIPLYVPYDGYIDPNRF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEECCEEECCEEEEECCCCEECCCCE
TTFDLSEINVSKGFTSVLYGPNTLGGAINMVSRKPAERFEGSLKGGLTFSDEGLASEFAS
EEEECCCEECCCCCEEEEECCCCCCCHHHHHHCCCHHHHCCCCCCCCEECCCCHHHHHHH
LNLGSNQGTWYVQGSLSILDRDFMQLSDSFLATKSEDGSKRDNSDSRDFRGSLKVGYTPN
EECCCCCCEEEEECCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEECCCCC
STDEYSLSIISQQSSKGVPVYTGINPTQTVRYWRYGDWDKSSIYFIGKKALGSKSYLKAR
CCCCEEEEEEECCCCCCCEEEECCCHHHEEEEEECCCCCCCEEEEEECHHCCCHHHHHHH
AYYDNYYNTLQSYDDASYATQKTKKAFSSRYDDKTFGGSIEFGTEILSGNTLKIALHDKY
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECHHEECCCEEEEEEECCC
DMHNEIGNTGEMPKEFEDNTVSVAAENTWKASDNISVIAGVRQDFRHTIKAEDLVGGVIT
CHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHH
SFPLEDNQATNLQLAVVGRLSESQELTAYLTRTTRFPTLKDRYSYRLGNAFPNPELKPEQ
CCCCCCCCCCCEEEEEEECCCCCCHHEEEEECCCCCCCHHHHHHEECCCCCCCCCCCCCC
SLNYGLDYAIRPADQLKFQASVYQSKLSDVIQQVNNIAYVKGIWVYQFQNTGEATFTGFE
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEEECCCCEEEEEEE
CSVDWQPVSWLRAYSGYSYIDRKNDSNPSLRFTDIPRHKFTGYLQFLFNKDRWAIVESEY
EEECCCCHHHHHHHCCCCEEECCCCCCCCEEEEECCCHHHHHHHHEEECCCCEEEEECHH
YSRRYSTSDGKYTAGAYGLINLRASTVLYDTLSLQASVENVFDRNYEVAEGYPEAGRQYV
HHHCCCCCCCCEECCEEEEEEEEEEEEEEEHHHHHHHHHHHHCCCCCHHCCCCHHHHHEE
VSLAWAL
HEEEECC
>Mature Secondary Structure
MKKIVLLVLLLAATETVFAAELPSDLPVSGIKVFTAGEVTVSGKKDHAKETVAATEMEML
CHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECEEEECCCCHHHHHHHHHHHHHHH
DKKNIAQAVNMLPGINVSNVGGRNEGMVYVRGFDMRQVPLYLDGIPLYVPYDGYIDPNRF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEECCEEECCEEEEECCCCEECCCCE
TTFDLSEINVSKGFTSVLYGPNTLGGAINMVSRKPAERFEGSLKGGLTFSDEGLASEFAS
EEEECCCEECCCCCEEEEECCCCCCCHHHHHHCCCHHHHCCCCCCCCEECCCCHHHHHHH
LNLGSNQGTWYVQGSLSILDRDFMQLSDSFLATKSEDGSKRDNSDSRDFRGSLKVGYTPN
EECCCCCCEEEEECCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCEEECCCCC
STDEYSLSIISQQSSKGVPVYTGINPTQTVRYWRYGDWDKSSIYFIGKKALGSKSYLKAR
CCCCEEEEEEECCCCCCCEEEECCCHHHEEEEEECCCCCCCEEEEEECHHCCCHHHHHHH
AYYDNYYNTLQSYDDASYATQKTKKAFSSRYDDKTFGGSIEFGTEILSGNTLKIALHDKY
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECHHEECCCEEEEEEECCC
DMHNEIGNTGEMPKEFEDNTVSVAAENTWKASDNISVIAGVRQDFRHTIKAEDLVGGVIT
CHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHH
SFPLEDNQATNLQLAVVGRLSESQELTAYLTRTTRFPTLKDRYSYRLGNAFPNPELKPEQ
CCCCCCCCCCCEEEEEEECCCCCCHHEEEEECCCCCCCHHHHHHEECCCCCCCCCCCCCC
SLNYGLDYAIRPADQLKFQASVYQSKLSDVIQQVNNIAYVKGIWVYQFQNTGEATFTGFE
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEEECCCCEEEEEEE
CSVDWQPVSWLRAYSGYSYIDRKNDSNPSLRFTDIPRHKFTGYLQFLFNKDRWAIVESEY
EEECCCCHHHHHHHCCCCEEECCCCCCCCEEEEECCCHHHHHHHHEEECCCCEEEEECHH
YSRRYSTSDGKYTAGAYGLINLRASTVLYDTLSLQASVENVFDRNYEVAEGYPEAGRQYV
HHHCCCCCCCCEECCEEEEEEEEEEEEEEEHHHHHHHHHHHHCCCCCHHCCCCHHHHHEE
VSLAWAL
HEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA