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The map label for this gene is fecD [C]

Identifier: 119356283

GI number: 119356283

Start: 493033

End: 494043

Strand: Direct

Name: fecD [C]

Synonym: Cpha266_0445

Alternate gene names: 119356283

Gene position: 493033-494043 (Clockwise)

Preceding gene: 119356282

Following gene: 119356284

Centisome position: 15.73

GC content: 53.71

Gene sequence:

>1011_bases
ATGAGCGCACGATTGCTGATTGTCACCAGTCTGTTTGTTCTTGCTGCTGCGGCAATCCTGTCGCTTTTTGTCGGGAGGTA
TCAGGTTTCTCCCGCAGCACTGTTCCGTTATCTGGCAACAGGGTACAGCAGTGACGCGAATCTTGAGACCGTGTTGCTTG
ATATTCGTCTGCCAAGGCTCATTGCCTCGGTTGCTGCCGGTGGAGCGCTCTCCCTGGCCGGTTCGGCTTATCAGGGCATG
TTTCGTAACCCCATGGTCAGTCCCGATATTCTTGGCGTATCATCAGGTGCGGGATTTGGTGCCGCACTTGCCATCCTCCT
CTCACTTCCGCCTGCGGGGATACAGTTGTTCTCATTTTCGGGGGGCGTGACGGCAGTTCTCGTTGCTCTCGGTATTGCGA
GGACTATTGGCAGAAGTCATGATGCCACACTGGTGCTGGTGCTCTCAGGCATCATCATATCTTCGCTGTTTGGCGCGCTG
CTCTCGCTGCTTAAATATGCGGCTGATCCGGATGACAAGCTTCCGGCAATCATTTACTGGCTTATGGGCAGTTTTGCTGA
TAGCAGTATGAAAGATCTCGGTCTGATCATTCCGTTGCTTCTTGCTGGAGTTATTCCTCTCATGCTGGTCGGCTGGCGTC
TGAACGTGCTCTCGTTTGGCGATGAGGAGGCTCGTTCACTCGGGATTAACACGGGACTGATGCGCGTGCTGGTTATTGCA
TGCGCAACACTGGTGAGTGCCTGTATGATCGCGGTCAGCGGGATAATCGGGTGGGTAGGACTTGTCGTTCCGCACCTTGC
GCGATTTGTTGCCGGGCCTGACCATCGAGTCCTTTTGCCTGTCTCGTTTCTTTTTGGCGGCACCATCATGTTGTGTGCCG
ATGTTCTGGCCCGTTCACTGTTGCCGGTCGAAATTCCGGTCGGTATCATTACCGCCATTACCGGTGCTCCGTTTTTTCTC
TGGTTTCTTAAACAATCGACGGCAGCAGCATGGGATTCAAAAAGAGGGTAA

Upstream 100 bases:

>100_bases
GCGCTTTGATGAACCACCGTAAAGGGAGGAATGCGGAATGAAAGCAACTTGCTGGCAGGCGGATGGCTTGCGGTATCAAT
AACAGGAAAAGAGGGGGGTC

Downstream 100 bases:

>100_bases
CCCTTGACATCACTCATGCCGATTTCGGCTATCAGGGAAGAGCCGTGCTTCGCGACGTCACTTTTCGGATGGATTCCGGC
GATATTGTCTGCGTTCTTGG

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSARLLIVTSLFVLAAAAILSLFVGRYQVSPAALFRYLATGYSSDANLETVLLDIRLPRLIASVAAGGALSLAGSAYQGM
FRNPMVSPDILGVSSGAGFGAALAILLSLPPAGIQLFSFSGGVTAVLVALGIARTIGRSHDATLVLVLSGIIISSLFGAL
LSLLKYAADPDDKLPAIIYWLMGSFADSSMKDLGLIIPLLLAGVIPLMLVGWRLNVLSFGDEEARSLGINTGLMRVLVIA
CATLVSACMIAVSGIIGWVGLVVPHLARFVAGPDHRVLLPVSFLFGGTIMLCADVLARSLLPVEIPVGIITAITGAPFFL
WFLKQSTAAAWDSKRG

Sequences:

>Translated_336_residues
MSARLLIVTSLFVLAAAAILSLFVGRYQVSPAALFRYLATGYSSDANLETVLLDIRLPRLIASVAAGGALSLAGSAYQGM
FRNPMVSPDILGVSSGAGFGAALAILLSLPPAGIQLFSFSGGVTAVLVALGIARTIGRSHDATLVLVLSGIIISSLFGAL
LSLLKYAADPDDKLPAIIYWLMGSFADSSMKDLGLIIPLLLAGVIPLMLVGWRLNVLSFGDEEARSLGINTGLMRVLVIA
CATLVSACMIAVSGIIGWVGLVVPHLARFVAGPDHRVLLPVSFLFGGTIMLCADVLARSLLPVEIPVGIITAITGAPFFL
WFLKQSTAAAWDSKRG
>Mature_335_residues
SARLLIVTSLFVLAAAAILSLFVGRYQVSPAALFRYLATGYSSDANLETVLLDIRLPRLIASVAAGGALSLAGSAYQGMF
RNPMVSPDILGVSSGAGFGAALAILLSLPPAGIQLFSFSGGVTAVLVALGIARTIGRSHDATLVLVLSGIIISSLFGALL
SLLKYAADPDDKLPAIIYWLMGSFADSSMKDLGLIIPLLLAGVIPLMLVGWRLNVLSFGDEEARSLGINTGLMRVLVIAC
ATLVSACMIAVSGIIGWVGLVVPHLARFVAGPDHRVLLPVSFLFGGTIMLCADVLARSLLPVEIPVGIITAITGAPFFLW
FLKQSTAAAWDSKRG

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=324, Percent_Identity=35.8024691358025, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790741, Length=311, Percent_Identity=35.3697749196142, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788004, Length=301, Percent_Identity=33.5548172757475, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786347, Length=290, Percent_Identity=31.3793103448276, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786805, Length=312, Percent_Identity=33.0128205128205, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786804, Length=329, Percent_Identity=26.7477203647416, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35007; Mature: 34876

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARLLIVTSLFVLAAAAILSLFVGRYQVSPAALFRYLATGYSSDANLETVLLDIRLPRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
IASVAAGGALSLAGSAYQGMFRNPMVSPDILGVSSGAGFGAALAILLSLPPAGIQLFSFS
HHHHHCCCHHHHCCHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHCCCCCEEEEECC
GGVTAVLVALGIARTIGRSHDATLVLVLSGIIISSLFGALLSLLKYAADPDDKLPAIIYW
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LMGSFADSSMKDLGLIIPLLLAGVIPLMLVGWRLNVLSFGDEEARSLGINTGLMRVLVIA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH
CATLVSACMIAVSGIIGWVGLVVPHLARFVAGPDHRVLLPVSFLFGGTIMLCADVLARSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHHHHHHC
LPVEIPVGIITAITGAPFFLWFLKQSTAAAWDSKRG
CCHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SARLLIVTSLFVLAAAAILSLFVGRYQVSPAALFRYLATGYSSDANLETVLLDIRLPRL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
IASVAAGGALSLAGSAYQGMFRNPMVSPDILGVSSGAGFGAALAILLSLPPAGIQLFSFS
HHHHHCCCHHHHCCHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHCCCCCEEEEECC
GGVTAVLVALGIARTIGRSHDATLVLVLSGIIISSLFGALLSLLKYAADPDDKLPAIIYW
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LMGSFADSSMKDLGLIIPLLLAGVIPLMLVGWRLNVLSFGDEEARSLGINTGLMRVLVIA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHH
CATLVSACMIAVSGIIGWVGLVVPHLARFVAGPDHRVLLPVSFLFGGTIMLCADVLARSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHHHHHHC
LPVEIPVGIITAITGAPFFLWFLKQSTAAAWDSKRG
CCHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]