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The map label for this gene is gluQ [H]

Identifier: 118581771

GI number: 118581771

Start: 3722427

End: 3723356

Strand: Reverse

Name: gluQ [H]

Synonym: Ppro_3371

Alternate gene names: 118581771

Gene position: 3723356-3722427 (Counterclockwise)

Preceding gene: 118581772

Following gene: 118581763

Centisome position: 92.9

GC content: 66.45

Gene sequence:

>930_bases
ATGTTCCGAACAACTCCCCTCATCGGCCGTTTTGCCCCCTCACCCACCGGAGCGCTGCATACCGGATCGCTGGTCAGCGC
CGTGGGGAGCTGGCTGATGGCCAAAAGCGCCGGCGGCCAGTGGCTTGTGCGCATCGACGACCTGGACAGCCAGCGCCAGG
TGCCGGGCATGGCCGACGACATCCTGGCCACCCTGGAGCGATTCGCCCTGTTCTGGGACGGCGAGATCTCCCGCCAGAGC
CTGAATTTGGAACTCTACGAGCAGGCTTTCCAGGAGTTGAAGAGAAAGGCTCTGCTCTATCCCTGCTGCTGCTCCCGCAG
GGAGATCTCCCAGGCGGCCTCGGCCCCACATCCCACGGACGACTGCCTCCCCTACCCGGGCAGTTGCCGCAACGGCATGC
CGGAAGGAAGAACGGTGCGCTCCTGGCGGGTGCGGGTGACGGACGAGCCGGTCTGTTTCCATGACCTGCGGCGGGGGATG
ATCTGCCAGAATCTTTTGACGGGGTGCGGGGATTTCCCGCTGCGGCGGGCTGACGGGGAGTTCGCCTACCAGCTGGCGGT
GGTGCTGGACGACCGGATCAGCGGTGTCAATCAGGTGGTGCGGGGGGATGACCTGCTGGCGTCAACGCCGCGCCAGATCC
ATCTGCAGCGCCTGCTCGCCCTGCCTCAACCGGAGTACTGCCATCTGCCGCTGGTGACCGGGCCGGGCGGGACCAAGCTG
AGCAAGCGGGACAACCTGGTGTCCCATCATCTGGGGAACTGGAAGGACAGGGAAGGGGTGCTGCTGCACAGGGTGCTGCG
CTTCCTGGGGCAGGAACCGCCGGCGGAACTGAGCGGCGCCTCCTGTCCTCAGATCCTGGCCTGGGGGGCGGCCCATTTCG
ATCTCCGCAAGCTGCCCCGGAAGGGTGGGGAGTTGACGCTCGTCAGCTGA

Upstream 100 bases:

>100_bases
AACAGCATAATTCTCCCGTTGTTTCAGTCTCTCTTCGTGCCTCTGTGCCTCCGTGTGAATCCATCTGCTATTTTCTCCTG
TTTTTAAAACGTTACGCCCT

Downstream 100 bases:

>100_bases
CAATTTCCCCTTCTTCGTGCCATCTTGATATCAGCTTTGATGTGAAACGGGAATTACCTGCCTTTTCCTATTCCCATCAA
CTCGGCCATGCGCACGATTG

Product: glutamate--tRNA ligase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MFRTTPLIGRFAPSPTGALHTGSLVSAVGSWLMAKSAGGQWLVRIDDLDSQRQVPGMADDILATLERFALFWDGEISRQS
LNLELYEQAFQELKRKALLYPCCCSRREISQAASAPHPTDDCLPYPGSCRNGMPEGRTVRSWRVRVTDEPVCFHDLRRGM
ICQNLLTGCGDFPLRRADGEFAYQLAVVLDDRISGVNQVVRGDDLLASTPRQIHLQRLLALPQPEYCHLPLVTGPGGTKL
SKRDNLVSHHLGNWKDREGVLLHRVLRFLGQEPPAELSGASCPQILAWGAAHFDLRKLPRKGGELTLVS

Sequences:

>Translated_309_residues
MFRTTPLIGRFAPSPTGALHTGSLVSAVGSWLMAKSAGGQWLVRIDDLDSQRQVPGMADDILATLERFALFWDGEISRQS
LNLELYEQAFQELKRKALLYPCCCSRREISQAASAPHPTDDCLPYPGSCRNGMPEGRTVRSWRVRVTDEPVCFHDLRRGM
ICQNLLTGCGDFPLRRADGEFAYQLAVVLDDRISGVNQVVRGDDLLASTPRQIHLQRLLALPQPEYCHLPLVTGPGGTKL
SKRDNLVSHHLGNWKDREGVLLHRVLRFLGQEPPAELSGASCPQILAWGAAHFDLRKLPRKGGELTLVS
>Mature_309_residues
MFRTTPLIGRFAPSPTGALHTGSLVSAVGSWLMAKSAGGQWLVRIDDLDSQRQVPGMADDILATLERFALFWDGEISRQS
LNLELYEQAFQELKRKALLYPCCCSRREISQAASAPHPTDDCLPYPGSCRNGMPEGRTVRSWRVRVTDEPVCFHDLRRGM
ICQNLLTGCGDFPLRRADGEFAYQLAVVLDDRISGVNQVVRGDDLLASTPRQIHLQRLLALPQPEYCHLPLVTGPGGTKL
SKRDNLVSHHLGNWKDREGVLLHRVLRFLGQEPPAELSGASCPQILAWGAAHFDLRKLPRKGGELTLVS

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=257, Percent_Identity=33.4630350194552, Blast_Score=124, Evalue=9e-29,
Organism=Escherichia coli, GI226510925, Length=298, Percent_Identity=39.9328859060403, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1788743, Length=263, Percent_Identity=31.9391634980989, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71993394, Length=258, Percent_Identity=31.7829457364341, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324540, Length=296, Percent_Identity=30.7432432432432, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24665321, Length=254, Percent_Identity=31.8897637795276, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 34284; Mature: 34284

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTTPLIGRFAPSPTGALHTGSLVSAVGSWLMAKSAGGQWLVRIDDLDSQRQVPGMADD
CCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
ILATLERFALFWDGEISRQSLNLELYEQAFQELKRKALLYPCCCSRREISQAASAPHPTD
HHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
DCLPYPGSCRNGMPEGRTVRSWRVRVTDEPVCFHDLRRGMICQNLLTGCGDFPLRRADGE
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FAYQLAVVLDDRISGVNQVVRGDDLLASTPRQIHLQRLLALPQPEYCHLPLVTGPGGTKL
EEEEEEEHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
SKRDNLVSHHLGNWKDREGVLLHRVLRFLGQEPPAELSGASCPQILAWGAAHFDLRKLPR
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHCC
KGGELTLVS
CCCCEEEEC
>Mature Secondary Structure
MFRTTPLIGRFAPSPTGALHTGSLVSAVGSWLMAKSAGGQWLVRIDDLDSQRQVPGMADD
CCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
ILATLERFALFWDGEISRQSLNLELYEQAFQELKRKALLYPCCCSRREISQAASAPHPTD
HHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
DCLPYPGSCRNGMPEGRTVRSWRVRVTDEPVCFHDLRRGMICQNLLTGCGDFPLRRADGE
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FAYQLAVVLDDRISGVNQVVRGDDLLASTPRQIHLQRLLALPQPEYCHLPLVTGPGGTKL
EEEEEEEHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
SKRDNLVSHHLGNWKDREGVLLHRVLRFLGQEPPAELSGASCPQILAWGAAHFDLRKLPR
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHCC
KGGELTLVS
CCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA