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The map label for this gene is degU [H]

Identifier: 118581564

GI number: 118581564

Start: 3472489

End: 3473100

Strand: Direct

Name: degU [H]

Synonym: Ppro_3163

Alternate gene names: 118581564

Gene position: 3472489-3473100 (Clockwise)

Preceding gene: 118581563

Following gene: 118581565

Centisome position: 86.64

GC content: 64.05

Gene sequence:

>612_bases
ATGATCCGGGTTCTCATCGCCGACGACCACGTCATGTTCCGCCAGGGACTCATCAACCTGCTGACAACCGCTGAAGACAT
CCATATCGCCGCCGAATGCGGCGACGGCGCCACGGCCCTGGAACTGATCCGCTCCCTGGAACCGGACATCGCCGTGCTGG
ACATCACCATGCCCAAGCTGGACGGCATCTCCATCACCCGCGCCATGGGGAACCTGGGGCTGGCGACGAGGGCGATCATC
CTGACCATGCACGATGACCCCCTGATGTATGGCCGGGCCGTCAGCGCCGGGGCGCACGGCTTCATCCTCAAGGACGATGC
CTACGAGGAACTCCTGAGCGCCCTGCGTACCGTGGCCGCGGGAGGAACCGCCATCAGCCGTGCCATACAGCATGCCGCAA
TCGAGCCGGAGCCGCCCGTGGCGGAGCTGACGGAACGGGAGAGAGAGATCCTGGGGCTGATAGCCCACGGCTGCACCAAC
CGCATGATCGCCCAACATCTGGGCATCAGCATCAAGACCGTCAACAACCATCGCACCAACCTGATGGGCAAGCTCAACCT
CCACTCCACTGCCGAACTGGTCCGCTACTCCCTCCTGACCGGTGGCCTGTAG

Upstream 100 bases:

>100_bases
TGGCTATCATGCGCGAACGGGCCGAACTTCTGGGCGGCGCTTTATCCGTCATCTCGCCACCCGGCATGGGCACCGCCATC
ACCGTGGAGGTACCGTTGCA

Downstream 100 bases:

>100_bases
CCCCCTCCGCGCTCCCCTTCCCCGCCTTGCCAGCAACGCTCCCGGCGCCCGTCTCCGACCCCAGAGGCGCGCATGGCGCT
CCTTCTAGGGTGTTCATCCT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIRVLIADDHVMFRQGLINLLTTAEDIHIAAECGDGATALELIRSLEPDIAVLDITMPKLDGISITRAMGNLGLATRAII
LTMHDDPLMYGRAVSAGAHGFILKDDAYEELLSALRTVAAGGTAISRAIQHAAIEPEPPVAELTEREREILGLIAHGCTN
RMIAQHLGISIKTVNNHRTNLMGKLNLHSTAELVRYSLLTGGL

Sequences:

>Translated_203_residues
MIRVLIADDHVMFRQGLINLLTTAEDIHIAAECGDGATALELIRSLEPDIAVLDITMPKLDGISITRAMGNLGLATRAII
LTMHDDPLMYGRAVSAGAHGFILKDDAYEELLSALRTVAAGGTAISRAIQHAAIEPEPPVAELTEREREILGLIAHGCTN
RMIAQHLGISIKTVNNHRTNLMGKLNLHSTAELVRYSLLTGGL
>Mature_203_residues
MIRVLIADDHVMFRQGLINLLTTAEDIHIAAECGDGATALELIRSLEPDIAVLDITMPKLDGISITRAMGNLGLATRAII
LTMHDDPLMYGRAVSAGAHGFILKDDAYEELLSALRTVAAGGTAISRAIQHAAIEPEPPVAELTEREREILGLIAHGCTN
RMIAQHLGISIKTVNNHRTNLMGKLNLHSTAELVRYSLLTGGL

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=37.5634517766497, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=32.6923076923077, Blast_Score=116, Evalue=8e-28,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=36.5979381443299, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=27.8606965174129, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=35.8695652173913, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788712, Length=196, Percent_Identity=26.0204081632653, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788546, Length=202, Percent_Identity=25.7425742574257, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21844; Mature: 21844

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLIADDHVMFRQGLINLLTTAEDIHIAAECGDGATALELIRSLEPDIAVLDITMPKL
CEEEEEECCHHHHHHHHHHHHHCHHHEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCC
DGISITRAMGNLGLATRAIILTMHDDPLMYGRAVSAGAHGFILKDDAYEELLSALRTVAA
CCCHHHHHHHCCCCEEEEEEEEECCCCCEECCEECCCCCEEEECCHHHHHHHHHHHHHHC
GGTAISRAIQHAAIEPEPPVAELTEREREILGLIAHGCTNRMIAQHLGISIKTVNNHRTN
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCC
LMGKLNLHSTAELVRYSLLTGGL
EEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRVLIADDHVMFRQGLINLLTTAEDIHIAAECGDGATALELIRSLEPDIAVLDITMPKL
CEEEEEECCHHHHHHHHHHHHHCHHHEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCC
DGISITRAMGNLGLATRAIILTMHDDPLMYGRAVSAGAHGFILKDDAYEELLSALRTVAA
CCCHHHHHHHCCCCEEEEEEEEECCCCCEECCEECCCCCEEEECCHHHHHHHHHHHHHHC
GGTAISRAIQHAAIEPEPPVAELTEREREILGLIAHGCTNRMIAQHLGISIKTVNNHRTN
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCC
LMGKLNLHSTAELVRYSLLTGGL
EEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]