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The map label for this gene is ppiD [H]

Identifier: 118581468

GI number: 118581468

Start: 3354440

End: 3356023

Strand: Direct

Name: ppiD [H]

Synonym: Ppro_3065

Alternate gene names: 118581468

Gene position: 3354440-3356023 (Clockwise)

Preceding gene: 118581451

Following gene: 118581469

Centisome position: 83.69

GC content: 59.41

Gene sequence:

>1584_bases
ATGCTGGATCTCATACGTCAGAAAAAGCAATCCATCATCATCAAGGTGGTATTTGTCGTCATCGTGCTTTCCTTCATCGG
CACCATGTTCCTGGTATGGGGCAAGGGGAGCGACGGGTCCGGGAGTTCCATGGCCTACGCGGCCAAGGTGAACAGGCACA
AAATCTCCCTGGAGGAATTCCAGAACGCCTACCAGCGCATGAGAAACATCTACCAACAGATCTACGGCCAGTCCCTGACG
CCGGAAATCGAGAAAACGCTGGGACTGAAAAAGGCGGCCCTGAACAGCTTGATCGACACGGCCCTGATCCTGAAAGAAGC
CAAGAAGATGGGCATCACCGCCAGCAAGGACGAGGTCTCCGGAGCCATCGCCGCCATGCCCATGTTCCAGAAGGACGGCG
TTTTCAGCTTCGACCTCTACCAGCAGTTGCTGAAGAGCAACCGCATAACCGCCAAGGAGTTCGAGGAAGCGCAACAGCGT
GAGCTGATTCTCAAGAAAACCCGCCAAGCCATCATAAACAAGGTCGCGGTCAGCGACCAGGAGGCCCTGGACCTCTTCAG
AAAGGAAAACGACAGGATCGAGCTGGAGTACCTGAGCTACGGCCCGGCGGACGTCATGGGAGAGATTCGGCCGACCGAAG
CCGAACTGAAGGAGTTCCTGCAAAAGAACCAGGACAGGTTCAGGACCGCCGAAAAAGCTGAAATTTCCTACGTGCTCATC
GACCCGGCCTCCCAGGCGGCCAGACAGAGCCTGACCGAGGATGAGATCCAGACCTTCTACCAGAAGAACATCGACCGCTG
GCAGGGCAAGGACGGTATCCTGCCGCTGGCCGATGTCAGGGAACGGGTCAGGGCCGAGGCCCTGAAACAGAAGGCCGCCC
GCCAGGCATTCGAACTGGCCGCCGACACCCTCTTCAAGAACATCAAGTCAGGCGACCTCAACCTGATCGCCGCTAAACTG
AACCTCAAGCCCCAGCAGACGCCCCTCTTCTCCGCGGACGCTTCGCCGCCAGCGCTGGCGGGCGAGACCGCCCTGATCAG
GAAGGCATTCGAACTCAAGCAGGGTGAACTGGGCGGACCGGTGGAAACCGGCCGGGGAATCTACATCGTCAAAGTCAGAC
AGCGCATCCCTTCCCAGGTACGGCCGTTGAACGAGATCAAGGCTCAGGTGGAACAGAGCTTCAAGGCTGCCAAGGCGGTT
GATCTGGCCCGCGGCAAGGCCGAGCAGGCTGCCCGTCAGCTTGCGGCAAAGAAACCGCTCTCCAGCCAGAGCACCTCTAG
CTTCGGCTTCTCGGCCAAGGGGGACGTCCCTTCCATCGGAAACGCGCCCGACCTGATGGAGGCAGCCTTCAGGCTGACCA
GCGCCAGTCCGGCCGCCACTGCCCCCTTCAAGGTCGGCGACCGCTGGTATGCCATCCGCCTGAAGAGCCGCAGCGAAGCG
CCCCGTGCCGAGTTCGACAGGACAAAAACAGCCATCAAGCAGGGGATGCTGCCCGTAAAACAGCAGGAGGCTCTCACAAC
CTGGGTGAAACAGTTGCGAGGCAAGGCAAAGATCGAAATCAATCAGGCACTCGTCGCCGACTAA

Upstream 100 bases:

>100_bases
AGCTTGCAATCGCTAGGGACGTATAGTAGTATTCGTTTTCCCGCCGCGCAGAGCGGTTTTTTTGTTTCATCCCACCAACC
AACGGAGGTGCGCCGGAGCC

Downstream 100 bases:

>100_bases
ACAGGAGAAACATATGTCACACCCCGTCATGCACACCGATTTTCCCGGGCTGAAACTTTTGGCCCGCGGCAAGGTGCGAG
ACATCTACGACCTGGGAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MLDLIRQKKQSIIIKVVFVVIVLSFIGTMFLVWGKGSDGSGSSMAYAAKVNRHKISLEEFQNAYQRMRNIYQQIYGQSLT
PEIEKTLGLKKAALNSLIDTALILKEAKKMGITASKDEVSGAIAAMPMFQKDGVFSFDLYQQLLKSNRITAKEFEEAQQR
ELILKKTRQAIINKVAVSDQEALDLFRKENDRIELEYLSYGPADVMGEIRPTEAELKEFLQKNQDRFRTAEKAEISYVLI
DPASQAARQSLTEDEIQTFYQKNIDRWQGKDGILPLADVRERVRAEALKQKAARQAFELAADTLFKNIKSGDLNLIAAKL
NLKPQQTPLFSADASPPALAGETALIRKAFELKQGELGGPVETGRGIYIVKVRQRIPSQVRPLNEIKAQVEQSFKAAKAV
DLARGKAEQAARQLAAKKPLSSQSTSSFGFSAKGDVPSIGNAPDLMEAAFRLTSASPAATAPFKVGDRWYAIRLKSRSEA
PRAEFDRTKTAIKQGMLPVKQQEALTTWVKQLRGKAKIEINQALVAD

Sequences:

>Translated_527_residues
MLDLIRQKKQSIIIKVVFVVIVLSFIGTMFLVWGKGSDGSGSSMAYAAKVNRHKISLEEFQNAYQRMRNIYQQIYGQSLT
PEIEKTLGLKKAALNSLIDTALILKEAKKMGITASKDEVSGAIAAMPMFQKDGVFSFDLYQQLLKSNRITAKEFEEAQQR
ELILKKTRQAIINKVAVSDQEALDLFRKENDRIELEYLSYGPADVMGEIRPTEAELKEFLQKNQDRFRTAEKAEISYVLI
DPASQAARQSLTEDEIQTFYQKNIDRWQGKDGILPLADVRERVRAEALKQKAARQAFELAADTLFKNIKSGDLNLIAAKL
NLKPQQTPLFSADASPPALAGETALIRKAFELKQGELGGPVETGRGIYIVKVRQRIPSQVRPLNEIKAQVEQSFKAAKAV
DLARGKAEQAARQLAAKKPLSSQSTSSFGFSAKGDVPSIGNAPDLMEAAFRLTSASPAATAPFKVGDRWYAIRLKSRSEA
PRAEFDRTKTAIKQGMLPVKQQEALTTWVKQLRGKAKIEINQALVAD
>Mature_527_residues
MLDLIRQKKQSIIIKVVFVVIVLSFIGTMFLVWGKGSDGSGSSMAYAAKVNRHKISLEEFQNAYQRMRNIYQQIYGQSLT
PEIEKTLGLKKAALNSLIDTALILKEAKKMGITASKDEVSGAIAAMPMFQKDGVFSFDLYQQLLKSNRITAKEFEEAQQR
ELILKKTRQAIINKVAVSDQEALDLFRKENDRIELEYLSYGPADVMGEIRPTEAELKEFLQKNQDRFRTAEKAEISYVLI
DPASQAARQSLTEDEIQTFYQKNIDRWQGKDGILPLADVRERVRAEALKQKAARQAFELAADTLFKNIKSGDLNLIAAKL
NLKPQQTPLFSADASPPALAGETALIRKAFELKQGELGGPVETGRGIYIVKVRQRIPSQVRPLNEIKAQVEQSFKAAKAV
DLARGKAEQAARQLAAKKPLSSQSTSSFGFSAKGDVPSIGNAPDLMEAAFRLTSASPAATAPFKVGDRWYAIRLKSRSEA
PRAEFDRTKTAIKQGMLPVKQQEALTTWVKQLRGKAKIEINQALVAD

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=508, Percent_Identity=25.7874015748031, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 58597; Mature: 58597

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLIRQKKQSIIIKVVFVVIVLSFIGTMFLVWGKGSDGSGSSMAYAAKVNRHKISLEEF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCHHCCCHHHH
QNAYQRMRNIYQQIYGQSLTPEIEKTLGLKKAALNSLIDTALILKEAKKMGITASKDEVS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GAIAAMPMFQKDGVFSFDLYQQLLKSNRITAKEFEEAQQRELILKKTRQAIINKVAVSDQ
HHHHHCCCHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EALDLFRKENDRIELEYLSYGPADVMGEIRPTEAELKEFLQKNQDRFRTAEKAEISYVLI
HHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHCEEEEEEE
DPASQAARQSLTEDEIQTFYQKNIDRWQGKDGILPLADVRERVRAEALKQKAARQAFELA
CCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADTLFKNIKSGDLNLIAAKLNLKPQQTPLFSADASPPALAGETALIRKAFELKQGELGGP
HHHHHHHCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
VETGRGIYIVKVRQRIPSQVRPLNEIKAQVEQSFKAAKAVDLARGKAEQAARQLAAKKPL
CCCCCCEEEEEHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
SSQSTSSFGFSAKGDVPSIGNAPDLMEAAFRLTSASPAATAPFKVGDRWYAIRLKSRSEA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCEEEEEEECCCCCC
PRAEFDRTKTAIKQGMLPVKQQEALTTWVKQLRGKAKIEINQALVAD
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECHHHCCC
>Mature Secondary Structure
MLDLIRQKKQSIIIKVVFVVIVLSFIGTMFLVWGKGSDGSGSSMAYAAKVNRHKISLEEF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEECCHHCCCHHHH
QNAYQRMRNIYQQIYGQSLTPEIEKTLGLKKAALNSLIDTALILKEAKKMGITASKDEVS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GAIAAMPMFQKDGVFSFDLYQQLLKSNRITAKEFEEAQQRELILKKTRQAIINKVAVSDQ
HHHHHCCCHHCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EALDLFRKENDRIELEYLSYGPADVMGEIRPTEAELKEFLQKNQDRFRTAEKAEISYVLI
HHHHHHHCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHCEEEEEEE
DPASQAARQSLTEDEIQTFYQKNIDRWQGKDGILPLADVRERVRAEALKQKAARQAFELA
CCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADTLFKNIKSGDLNLIAAKLNLKPQQTPLFSADASPPALAGETALIRKAFELKQGELGGP
HHHHHHHCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
VETGRGIYIVKVRQRIPSQVRPLNEIKAQVEQSFKAAKAVDLARGKAEQAARQLAAKKPL
CCCCCCEEEEEHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
SSQSTSSFGFSAKGDVPSIGNAPDLMEAAFRLTSASPAATAPFKVGDRWYAIRLKSRSEA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCEEEEEEECCCCCC
PRAEFDRTKTAIKQGMLPVKQQEALTTWVKQLRGKAKIEINQALVAD
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]