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The map label for this gene is pgsA [H]

Identifier: 118580188

GI number: 118580188

Start: 1899193

End: 1899786

Strand: Reverse

Name: pgsA [H]

Synonym: Ppro_1768

Alternate gene names: 118580188

Gene position: 1899786-1899193 (Counterclockwise)

Preceding gene: 118580189

Following gene: 118580185

Centisome position: 47.4

GC content: 58.25

Gene sequence:

>594_bases
ATGACGACACAGACGCAAACCCCGATTCTCAACCCGCCCAACATCCTGACCATGCTGCGCATCGCGGCCATACCGCTCCT
GGCGACGCTGCTCATGTCTCCGGAGCGCTCGGCGGGATTCTGGGCCGCTGCGGTCTTTGCGTTGGCCTCAATCACCGACT
GGCTGGACGGCTATCTGGCGCGACGTATGGAGATCGTCACGGTATTCGGCAAATTCCTCGATCCCATTGCCGACAAACTG
ATCGTCATGGCCGCCCTGATCATGATACTCCCCTTTGGCCGTGTTCCCGCATGGATGGTGCTGATCATCCTGGGACGGGA
AATCATCATCACCGGACTGCGCGGAATAGCCTCCAGCGAGGGCATCGTCATCCAGGCCAGCGACCTGGGCAAATTCAAGA
CCATCTTCCAGATTGTCGCCATACTGGGACTTTTGCTGCACTACGACTACAACTGGTTCTTCGGAATCCAGCACCCGCTG
CTGCAGGTCAACATGCACAACGTGGGGATGTTCTACCTCTGGATCGCAACCCTGCTCACCGTCTGGTCCGGCGGGGATTA
CCTGTTCCGCTTTATGAGAGTTATCGCCCGCTGA

Upstream 100 bases:

>100_bases
CAAAGTGGCCAGATACGGCGGCATTCCTCCCTATACCGAGACCCGTACCTATGTAAACCGGGTACTTTCCTACATGCAAT
CCTACCAGGCCAACTGATCG

Downstream 100 bases:

>100_bases
GACTCGCTCAGCGGGTGGATGTCCCCATGAGCACCTCGATTTTCCTGCCGCCATGACTGAACAGCACCCGATCCCGCTGA
ACCTCGTCGACCCTGACCCC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTTQTQTPILNPPNILTMLRIAAIPLLATLLMSPERSAGFWAAAVFALASITDWLDGYLARRMEIVTVFGKFLDPIADKL
IVMAALIMILPFGRVPAWMVLIILGREIIITGLRGIASSEGIVIQASDLGKFKTIFQIVAILGLLLHYDYNWFFGIQHPL
LQVNMHNVGMFYLWIATLLTVWSGGDYLFRFMRVIAR

Sequences:

>Translated_197_residues
MTTQTQTPILNPPNILTMLRIAAIPLLATLLMSPERSAGFWAAAVFALASITDWLDGYLARRMEIVTVFGKFLDPIADKL
IVMAALIMILPFGRVPAWMVLIILGREIIITGLRGIASSEGIVIQASDLGKFKTIFQIVAILGLLLHYDYNWFFGIQHPL
LQVNMHNVGMFYLWIATLLTVWSGGDYLFRFMRVIAR
>Mature_196_residues
TTQTQTPILNPPNILTMLRIAAIPLLATLLMSPERSAGFWAAAVFALASITDWLDGYLARRMEIVTVFGKFLDPIADKLI
VMAALIMILPFGRVPAWMVLIILGREIIITGLRGIASSEGIVIQASDLGKFKTIFQIVAILGLLLHYDYNWFFGIQHPLL
QVNMHNVGMFYLWIATLLTVWSGGDYLFRFMRVIAR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=35.6756756756757, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320059, Length=112, Percent_Identity=36.6071428571429, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22097; Mature: 21966

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTQTPILNPPNILTMLRIAAIPLLATLLMSPERSAGFWAAAVFALASITDWLDGYLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRMEIVTVFGKFLDPIADKLIVMAALIMILPFGRVPAWMVLIILGREIIITGLRGIASSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GIVIQASDLGKFKTIFQIVAILGLLLHYDYNWFFGIQHPLLQVNMHNVGMFYLWIATLLT
CEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHEEEEHHHHHHHHHHHHHHHH
VWSGGDYLFRFMRVIAR
HHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TTQTQTPILNPPNILTMLRIAAIPLLATLLMSPERSAGFWAAAVFALASITDWLDGYLA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRMEIVTVFGKFLDPIADKLIVMAALIMILPFGRVPAWMVLIILGREIIITGLRGIASSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GIVIQASDLGKFKTIFQIVAILGLLLHYDYNWFFGIQHPLLQVNMHNVGMFYLWIATLLT
CEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHEEEEHHHHHHHHHHHHHHHH
VWSGGDYLFRFMRVIAR
HHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]