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The map label for this gene is sucC

Identifier: 118580136

GI number: 118580136

Start: 1840902

End: 1842086

Strand: Reverse

Name: sucC

Synonym: Ppro_1716

Alternate gene names: 118580136

Gene position: 1842086-1840902 (Counterclockwise)

Preceding gene: 118580137

Following gene: 118580135

Centisome position: 45.96

GC content: 64.98

Gene sequence:

>1185_bases
ATGAAAATCCATGAGTACCAGGCCAAGGATATCCTGGCTGGCTTCGGCATCGCCATCCCGCGCGGCCGGGTGGCCATGAA
CGCCAGTCAGGTGGAGCGCGCCGCCAGGGAGTTGGGCGGACATTGCGTCATCAAGGCTCAGGTCTACGCCGGCGGCCGCG
GCAAGGGAGGCGGCATCAGGGTGGCCCAGGATCCTGGCCAGGCCGGCGAGATCGCCAAAGAGCTGTTGGGCACAAAACTG
GTCACGCCCCAGACCGGGCCCGAGGGACTGGAGGTACGCCGCCTGCTGGTGGAGGAGGTCGTGGATATCGAAAGGGAACT
GTACCTCTCCATCACCCTGGACCGGGAGAGCTCCCGCTACTGCCTGATCGCATCGGCTGAGGGGGGCATGGACATCGAGG
AGATCGCCCGCACGGCGCCGGACAGGATCCGGATACTGACCATCGATCCCTTTATCGGGCTGCGTTCCTATCAGGCGCGC
AGGACCGCCTTGGGGCTGGGGCTGGTCGGCCCACTCTGCGAGGAGTGCGTGGAATTGATCCTCAACCTGTACCGCTGCCT
CCTGGAGAGGGACTGCTCCCTGGTGGAGATCAACCCGCTGGTGGTGACCAACGCCGGCTGGCTGGTGGCCATGGACACCA
AGATGACCTTTGACGACAACGCCCTGCAGCGCCACTGCGAGTACCCCGACCTGGTGGACTACTCCCAGCTCAACCCGCTG
GAGATCGCCGCCGCCAGGTTTGATCTCTCCTACATCAAACTCTCCGGCGCCATCGGCTGCATGGTCAACGGCGCCGGCCT
GGCCATGGCCACCCTGGACGTGCTCAAGGAGGCAGGTGGCGAGCCGGCCAACTTCCTGGACGTGGGGGGCGGCGCCAGCC
GGGAGAAGGTGGCCGAGGCCTTCCGCATCATCCTGCAGGACCGGGACGTGCGGGGAGTGTTCGTCAACATCTTCGGCGGG
ATCATGCGCTGCGACATCATCGCCCAGGGGATCATCGATGCCGCCTCCGGCGGTGGTTGCAGACTGCCGATAGTGGTGCG
CATGGATGGCAACCGGGTCGAGGAGGGGAAACAGTTGCTCCGTGAGTCCGGCCTGAACATCCGCATCGGCGAGAACATGG
GCGACGGAGCCCAACAGATCGTCGCCATGCTGAACCGGGAGGTGAACCAGCCATGTCAATCCTGA

Upstream 100 bases:

>100_bases
CCGCGCCTCGGAGGCTGAATACGCCAAGCTGGACCAGCAGAAACTGCTGCGCAAACGTCAGTAGTTCCAAATAGACATCC
TCAGAACCAGGAGGAACGCC

Downstream 100 bases:

>100_bases
TCGACGGAAACACTCGATTTGTGGTTCAGGGGATCACCGGCCGCAGCGGGCTGTTCCACGCCCAGCAGTGCCGGGCCTAC
GGCAGCCAGGTTGTAGGCGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKIHEYQAKDILAGFGIAIPRGRVAMNASQVERAARELGGHCVIKAQVYAGGRGKGGGIRVAQDPGQAGEIAKELLGTKL
VTPQTGPEGLEVRRLLVEEVVDIERELYLSITLDRESSRYCLIASAEGGMDIEEIARTAPDRIRILTIDPFIGLRSYQAR
RTALGLGLVGPLCEECVELILNLYRCLLERDCSLVEINPLVVTNAGWLVAMDTKMTFDDNALQRHCEYPDLVDYSQLNPL
EIAAARFDLSYIKLSGAIGCMVNGAGLAMATLDVLKEAGGEPANFLDVGGGASREKVAEAFRIILQDRDVRGVFVNIFGG
IMRCDIIAQGIIDAASGGGCRLPIVVRMDGNRVEEGKQLLRESGLNIRIGENMGDGAQQIVAMLNREVNQPCQS

Sequences:

>Translated_394_residues
MKIHEYQAKDILAGFGIAIPRGRVAMNASQVERAARELGGHCVIKAQVYAGGRGKGGGIRVAQDPGQAGEIAKELLGTKL
VTPQTGPEGLEVRRLLVEEVVDIERELYLSITLDRESSRYCLIASAEGGMDIEEIARTAPDRIRILTIDPFIGLRSYQAR
RTALGLGLVGPLCEECVELILNLYRCLLERDCSLVEINPLVVTNAGWLVAMDTKMTFDDNALQRHCEYPDLVDYSQLNPL
EIAAARFDLSYIKLSGAIGCMVNGAGLAMATLDVLKEAGGEPANFLDVGGGASREKVAEAFRIILQDRDVRGVFVNIFGG
IMRCDIIAQGIIDAASGGGCRLPIVVRMDGNRVEEGKQLLRESGLNIRIGENMGDGAQQIVAMLNREVNQPCQS
>Mature_394_residues
MKIHEYQAKDILAGFGIAIPRGRVAMNASQVERAARELGGHCVIKAQVYAGGRGKGGGIRVAQDPGQAGEIAKELLGTKL
VTPQTGPEGLEVRRLLVEEVVDIERELYLSITLDRESSRYCLIASAEGGMDIEEIARTAPDRIRILTIDPFIGLRSYQAR
RTALGLGLVGPLCEECVELILNLYRCLLERDCSLVEINPLVVTNAGWLVAMDTKMTFDDNALQRHCEYPDLVDYSQLNPL
EIAAARFDLSYIKLSGAIGCMVNGAGLAMATLDVLKEAGGEPANFLDVGGGASREKVAEAFRIILQDRDVRGVFVNIFGG
IMRCDIIAQGIIDAASGGGCRLPIVVRMDGNRVEEGKQLLRESGLNIRIGENMGDGAQQIVAMLNREVNQPCQS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=42.2976501305483, Blast_Score=305, Evalue=5e-83,
Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=40.920716112532, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI294862256, Length=391, Percent_Identity=40.6649616368286, Blast_Score=293, Evalue=1e-79,
Organism=Escherichia coli, GI1786948, Length=383, Percent_Identity=48.0417754569191, Blast_Score=344, Evalue=7e-96,
Organism=Caenorhabditis elegans, GI17567829, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17539378, Length=396, Percent_Identity=40.6565656565657, Blast_Score=296, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=41.3705583756345, Blast_Score=314, Evalue=1e-86,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=43.9897698209719, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=43.9897698209719, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI281361397, Length=392, Percent_Identity=44.1326530612245, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361395, Length=392, Percent_Identity=44.1326530612245, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=38.5786802030457, Blast_Score=290, Evalue=9e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_PELPD (A1APQ8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901386.1
- ProteinModelPortal:   A1APQ8
- SMR:   A1APQ8
- STRING:   A1APQ8
- GeneID:   4572765
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1716
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   LPIVVRM
- PhylomeDB:   A1APQ8
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42654; Mature: 42654

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKDILAGFGIAIPRGRVAMNASQVERAARELGGHCVIKAQVYAGGRGKGGGIR
CCCCHHHHHHHHHHCCEECCCCCEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
VAQDPGQAGEIAKELLGTKLVTPQTGPEGLEVRRLLVEEVVDIERELYLSITLDRESSRY
EECCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCE
CLIASAEGGMDIEEIARTAPDRIRILTIDPFIGLRSYQARRTALGLGLVGPLCEECVELI
EEEEECCCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNLYRCLLERDCSLVEINPLVVTNAGWLVAMDTKMTFDDNALQRHCEYPDLVDYSQLNPL
HHHHHHHHHCCCCEEEECEEEEECCCEEEEEECEEECCCHHHHHHCCCCCCCCCCCCCCH
EIAAARFDLSYIKLSGAIGCMVNGAGLAMATLDVLKEAGGEPANFLDVGGGASREKVAEA
HHHHHHHCEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHH
FRIILQDRDVRGVFVNIFGGIMRCDIIAQGIIDAASGGGCRLPIVVRMDGNRVEEGKQLL
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHH
RESGLNIRIGENMGDGAQQIVAMLNREVNQPCQS
HHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIHEYQAKDILAGFGIAIPRGRVAMNASQVERAARELGGHCVIKAQVYAGGRGKGGGIR
CCCCHHHHHHHHHHCCEECCCCCEEECHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCEE
VAQDPGQAGEIAKELLGTKLVTPQTGPEGLEVRRLLVEEVVDIERELYLSITLDRESSRY
EECCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCE
CLIASAEGGMDIEEIARTAPDRIRILTIDPFIGLRSYQARRTALGLGLVGPLCEECVELI
EEEEECCCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNLYRCLLERDCSLVEINPLVVTNAGWLVAMDTKMTFDDNALQRHCEYPDLVDYSQLNPL
HHHHHHHHHCCCCEEEECEEEEECCCEEEEEECEEECCCHHHHHHCCCCCCCCCCCCCCH
EIAAARFDLSYIKLSGAIGCMVNGAGLAMATLDVLKEAGGEPANFLDVGGGASREKVAEA
HHHHHHHCEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHH
FRIILQDRDVRGVFVNIFGGIMRCDIIAQGIIDAASGGGCRLPIVVRMDGNRVEEGKQLL
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHH
RESGLNIRIGENMGDGAQQIVAMLNREVNQPCQS
HHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA