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The map label for this gene is sucD [H]

Identifier: 118580135

GI number: 118580135

Start: 1840024

End: 1840914

Strand: Reverse

Name: sucD [H]

Synonym: Ppro_1715

Alternate gene names: 118580135

Gene position: 1840914-1840024 (Counterclockwise)

Preceding gene: 118580136

Following gene: 118580134

Centisome position: 45.93

GC content: 66.33

Gene sequence:

>891_bases
ATGTCAATCCTGATCGACGGAAACACTCGATTTGTGGTTCAGGGGATCACCGGCCGCAGCGGGCTGTTCCACGCCCAGCA
GTGCCGGGCCTACGGCAGCCAGGTTGTAGGCGGGGTGACGCCCGGCAAGGGGGGAAGCGAGATCGACGGTTTCCCGGTCT
TCGACACCCTGGAGCAGGCGGTGCGCGCGACAGGCGCCACGGCATCCCTGATCTTCGTCCCTCCCCCGGCGGCGGCGGAT
TCGATCCTCGAGGCGGTGGACGCCGGGCTTGAACTGTGCGTCTGCATCACCGAGGGGATACCGGTGCGGGACATGGTGCT
GGCGCGGGCAGTGCTGGAGGGAAGCAAAACCAGGCTGGTCGGCCCCAACAGCCCGGGCGTGATCACCCCCGGCCAGTGCA
AGATGGGCATCATGCCGGGCCAGATCCACGCACCGGGGAGGATCGGTGTCATCTCCCGCAGCGGCACCCTGACCTACGAG
ATCGTGCGCCAACTGACCGACAGGGGGCTGGGGCAGTCAACCTGCGTCGGCATCGGCGGCGACGCCATCATCGGCATGAA
GTTCAGCGACGTTCTCAAGCTGTTCAATGACGACCCGGACACCGACGGGGTGTTCATGGTCGGCGAGATCGGAGGCACCG
CCGAGGAGGAGGCTGCCCTCTGGATCAGGGAGAACATGACCAAGCCGGTGGCCGCCTTCGTGGCCGGCGTCAGCGCCCCT
CCCGGAAAGCGCATGGGGCACGCCGGCGCTATCATCAGCGCTGGCAAGGGCAAGGCGACCGACAAGATCCGCACCCTCAA
GGAGTGCGGCGTCACCGTGGCCGACAGCCCGATCCGCATGGGCGAGGCAATGATCGAAGCGCTTAGAAAAGCTGGATTGA
GCGTGGCTTGA

Upstream 100 bases:

>100_bases
AGTTGCTCCGTGAGTCCGGCCTGAACATCCGCATCGGCGAGAACATGGGCGACGGAGCCCAACAGATCGTCGCCATGCTG
AACCGGGAGGTGAACCAGCC

Downstream 100 bases:

>100_bases
GGAGAGTGGAGCACGTCGGAAACCTGTTGAATGTTGAGCTTTGACCCCTCCGACAACCCGTGGCTGAGCGCATGCAGAAA
ACCCCCGAACTGGCTGATAG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSILIDGNTRFVVQGITGRSGLFHAQQCRAYGSQVVGGVTPGKGGSEIDGFPVFDTLEQAVRATGATASLIFVPPPAAAD
SILEAVDAGLELCVCITEGIPVRDMVLARAVLEGSKTRLVGPNSPGVITPGQCKMGIMPGQIHAPGRIGVISRSGTLTYE
IVRQLTDRGLGQSTCVGIGGDAIIGMKFSDVLKLFNDDPDTDGVFMVGEIGGTAEEEAALWIRENMTKPVAAFVAGVSAP
PGKRMGHAGAIISAGKGKATDKIRTLKECGVTVADSPIRMGEAMIEALRKAGLSVA

Sequences:

>Translated_296_residues
MSILIDGNTRFVVQGITGRSGLFHAQQCRAYGSQVVGGVTPGKGGSEIDGFPVFDTLEQAVRATGATASLIFVPPPAAAD
SILEAVDAGLELCVCITEGIPVRDMVLARAVLEGSKTRLVGPNSPGVITPGQCKMGIMPGQIHAPGRIGVISRSGTLTYE
IVRQLTDRGLGQSTCVGIGGDAIIGMKFSDVLKLFNDDPDTDGVFMVGEIGGTAEEEAALWIRENMTKPVAAFVAGVSAP
PGKRMGHAGAIISAGKGKATDKIRTLKECGVTVADSPIRMGEAMIEALRKAGLSVA
>Mature_295_residues
SILIDGNTRFVVQGITGRSGLFHAQQCRAYGSQVVGGVTPGKGGSEIDGFPVFDTLEQAVRATGATASLIFVPPPAAADS
ILEAVDAGLELCVCITEGIPVRDMVLARAVLEGSKTRLVGPNSPGVITPGQCKMGIMPGQIHAPGRIGVISRSGTLTYEI
VRQLTDRGLGQSTCVGIGGDAIIGMKFSDVLKLFNDDPDTDGVFMVGEIGGTAEEEAALWIRENMTKPVAAFVAGVSAPP
GKRMGHAGAIISAGKGKATDKIRTLKECGVTVADSPIRMGEAMIEALRKAGLSVA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=293, Percent_Identity=54.6075085324232, Blast_Score=277, Evalue=8e-75,
Organism=Homo sapiens, GI38569421, Length=248, Percent_Identity=31.0483870967742, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI38569423, Length=248, Percent_Identity=31.0483870967742, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=58.477508650519, Blast_Score=355, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=54.4520547945205, Blast_Score=304, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=51.7123287671233, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17557344, Length=271, Percent_Identity=25.0922509225092, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=302, Percent_Identity=25.4966887417219, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=298, Percent_Identity=47.986577181208, Blast_Score=265, Evalue=6e-72,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=50, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI28574296, Length=297, Percent_Identity=53.1986531986532, Blast_Score=291, Evalue=3e-79,
Organism=Drosophila melanogaster, GI281363477, Length=306, Percent_Identity=26.1437908496732, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281363475, Length=306, Percent_Identity=26.1437908496732, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281363473, Length=306, Percent_Identity=26.1437908496732, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30518; Mature: 30387

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIDGNTRFVVQGITGRSGLFHAQQCRAYGSQVVGGVTPGKGGSEIDGFPVFDTLEQA
CEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
VRATGATASLIFVPPPAAADSILEAVDAGLELCVCITEGIPVRDMVLARAVLEGSKTRLV
HHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNSPGVITPGQCKMGIMPGQIHAPGRIGVISRSGTLTYEIVRQLTDRGLGQSTCVGIGG
CCCCCCEECCCCCEECCCCCCEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCC
DAIIGMKFSDVLKLFNDDPDTDGVFMVGEIGGTAEEEAALWIRENMTKPVAAFVAGVSAP
CEEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCC
PGKRMGHAGAIISAGKGKATDKIRTLKECGVTVADSPIRMGEAMIEALRKAGLSVA
CCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SILIDGNTRFVVQGITGRSGLFHAQQCRAYGSQVVGGVTPGKGGSEIDGFPVFDTLEQA
EEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
VRATGATASLIFVPPPAAADSILEAVDAGLELCVCITEGIPVRDMVLARAVLEGSKTRLV
HHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNSPGVITPGQCKMGIMPGQIHAPGRIGVISRSGTLTYEIVRQLTDRGLGQSTCVGIGG
CCCCCCEECCCCCEECCCCCCEECCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCC
DAIIGMKFSDVLKLFNDDPDTDGVFMVGEIGGTAEEEAALWIRENMTKPVAAFVAGVSAP
CEEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCC
PGKRMGHAGAIISAGKGKATDKIRTLKECGVTVADSPIRMGEAMIEALRKAGLSVA
CCCCCCCCCCEEECCCCCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]