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The map label for this gene is gap [H]

Identifier: 118580134

GI number: 118580134

Start: 1838810

End: 1839829

Strand: Reverse

Name: gap [H]

Synonym: Ppro_1714

Alternate gene names: 118580134

Gene position: 1839829-1838810 (Counterclockwise)

Preceding gene: 118580135

Following gene: 118580133

Centisome position: 45.9

GC content: 42.65

Gene sequence:

>1020_bases
ATGTATAAAGTCGCAATTAATGGTTTTGGGAGAATAGGAAGACTTGCATTTCGAAAAATCTTTGAAGATGATCGTTTTGA
AGTTGTGGCAATTAACGATTTAACAGAGCCAAAGATGCTTGCTCATCTTCTGAAGTATGACAGTGTACAAGGTCGTTTTG
CAGGACATACTGTCGGTTTTGATGATGACTCTCTTGTCGTTGATGACAAGAAAATAGGAGTTTACAAAGACGCAGATCCC
AAGAACCTTCCGTGGGACAAACTTGGGGTAGACATTGTTTTAGAGTGTACAGGGTTTTTCTGCTCAAAAACCAAGAGTCA
GGCGCATATTGATGCAGGGGCAAAGAGGGTTCTTATTTCAGCTCCTGCCGGCAATGATCTTCCAACCATTGTATATGGCG
TGAATCATCATACTCTGAAATATGATGACCTCATTGTCTCCGGTGCATCCTGCACAACCAATTGCCTTGCTCCTCTGGCA
AAGACATTGAATGATTATCGTGAGTTACGAACAGGATTCATGACTACGATTCATGCATATACGGGCGACCAAATGCTGCT
TGATGGACCGCACCGTAAAGGTGATTTTCGCCGTGCAAGAGCCGGTGCAATTAACATTGTGCCTAATTCAACCGGTGCTG
CGAAAGCTATCGGCCTTGTCATTCCTGAACTTGATGGAAAGCTTATCGGATCAGCGCAACGTGTACCTGTTCCTTCTGGT
TCCATCACTATTCTTGATGCCACTTTAAAGGATGAGACCGAGACTGTATCTGTTGAAGGAATCAATGAAGCAATGAAAAG
AGCTGCTGATGATTCCTTTGGATATTCTGACGAGGAGTTGGTGTCAAGCGATATAATTGGTATAAGCTATGGTTCACTTT
TTGATTCTACGCAAACACTTGCGCAGCGGTGTGGAACCAAGATTTATGAGGTTAGAGTTGTTTCCTGGTATGACAATGAA
ATGAGCTATGTAAGTCAATTAATCAGAACTTTAGGCCTCATGGGAAGTCTGATGAGATAA

Upstream 100 bases:

>100_bases
TGATAGGGTTCGATCAGTAACAGATGAACTGTAACAACTCAACAACTTGGAAGCATTCCCCCCCTGGATTCAAGATATAT
ATTAAACTGGAGGAACTACT

Downstream 100 bases:

>100_bases
CCAGAATCAGCAAATATCTTGGCGGCTAATGGAAACAGTAGGATCAACTCTCCATTTTTCAACGTAGTTCTGTATGTCCC
CGGAACCCCCTCCCGGCACA

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MYKVAINGFGRIGRLAFRKIFEDDRFEVVAINDLTEPKMLAHLLKYDSVQGRFAGHTVGFDDDSLVVDDKKIGVYKDADP
KNLPWDKLGVDIVLECTGFFCSKTKSQAHIDAGAKRVLISAPAGNDLPTIVYGVNHHTLKYDDLIVSGASCTTNCLAPLA
KTLNDYRELRTGFMTTIHAYTGDQMLLDGPHRKGDFRRARAGAINIVPNSTGAAKAIGLVIPELDGKLIGSAQRVPVPSG
SITILDATLKDETETVSVEGINEAMKRAADDSFGYSDEELVSSDIIGISYGSLFDSTQTLAQRCGTKIYEVRVVSWYDNE
MSYVSQLIRTLGLMGSLMR

Sequences:

>Translated_339_residues
MYKVAINGFGRIGRLAFRKIFEDDRFEVVAINDLTEPKMLAHLLKYDSVQGRFAGHTVGFDDDSLVVDDKKIGVYKDADP
KNLPWDKLGVDIVLECTGFFCSKTKSQAHIDAGAKRVLISAPAGNDLPTIVYGVNHHTLKYDDLIVSGASCTTNCLAPLA
KTLNDYRELRTGFMTTIHAYTGDQMLLDGPHRKGDFRRARAGAINIVPNSTGAAKAIGLVIPELDGKLIGSAQRVPVPSG
SITILDATLKDETETVSVEGINEAMKRAADDSFGYSDEELVSSDIIGISYGSLFDSTQTLAQRCGTKIYEVRVVSWYDNE
MSYVSQLIRTLGLMGSLMR
>Mature_339_residues
MYKVAINGFGRIGRLAFRKIFEDDRFEVVAINDLTEPKMLAHLLKYDSVQGRFAGHTVGFDDDSLVVDDKKIGVYKDADP
KNLPWDKLGVDIVLECTGFFCSKTKSQAHIDAGAKRVLISAPAGNDLPTIVYGVNHHTLKYDDLIVSGASCTTNCLAPLA
KTLNDYRELRTGFMTTIHAYTGDQMLLDGPHRKGDFRRARAGAINIVPNSTGAAKAIGLVIPELDGKLIGSAQRVPVPSG
SITILDATLKDETETVSVEGINEAMKRAADDSFGYSDEELVSSDIIGISYGSLFDSTQTLAQRCGTKIYEVRVVSWYDNE
MSYVSQLIRTLGLMGSLMR

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=43.3628318584071, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI7669492, Length=341, Percent_Identity=41.0557184750733, Blast_Score=248, Evalue=7e-66,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=45.7575757575758, Blast_Score=273, Evalue=8e-75,
Organism=Escherichia coli, GI1789295, Length=343, Percent_Identity=38.7755102040816, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17534677, Length=346, Percent_Identity=43.3526011560694, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17534679, Length=346, Percent_Identity=43.0635838150289, Blast_Score=258, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=44.3786982248521, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17568413, Length=346, Percent_Identity=43.3526011560694, Blast_Score=254, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=44.7447447447448, Blast_Score=276, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=46.2462462462462, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=45.6456456456456, Blast_Score=271, Evalue=1e-73,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=44.5454545454545, Blast_Score=264, Evalue=6e-71,
Organism=Drosophila melanogaster, GI17933600, Length=346, Percent_Identity=43.0635838150289, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI18110149, Length=346, Percent_Identity=43.0635838150289, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI85725000, Length=340, Percent_Identity=43.8235294117647, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI22023983, Length=340, Percent_Identity=43.8235294117647, Blast_Score=252, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37056; Mature: 37056

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVAINGFGRIGRLAFRKIFEDDRFEVVAINDLTEPKMLAHLLKYDSVQGRFAGHTVGF
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCC
DDDSLVVDDKKIGVYKDADPKNLPWDKLGVDIVLECTGFFCSKTKSQAHIDAGAKRVLIS
CCCCEEEECCCCCEEECCCCCCCCHHHCCCEEEEEECCHHHHCCCCCHHHCCCCCEEEEE
APAGNDLPTIVYGVNHHTLKYDDLIVSGASCTTNCLAPLAKTLNDYRELRTGFMTTIHAY
CCCCCCCCEEEEECCCCEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
TGDQMLLDGPHRKGDFRRARAGAINIVPNSTGAAKAIGLVIPELDGKLIGSAQRVPVPSG
CCCEEEECCCCCCCCHHHHCCCEEEEEECCCCCHHEEEEEEECCCCCEECCCCCCCCCCC
SITILDATLKDETETVSVEGINEAMKRAADDSFGYSDEELVSSDIIGISYGSLFDSTQTL
CEEEEEEEECCCCCEEEECCHHHHHHHHCCCCCCCCHHHHHHHCEEEEECHHHHHHHHHH
AQRCGTKIYEVRVVSWYDNEMSYVSQLIRTLGLMGSLMR
HHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYKVAINGFGRIGRLAFRKIFEDDRFEVVAINDLTEPKMLAHLLKYDSVQGRFAGHTVGF
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCC
DDDSLVVDDKKIGVYKDADPKNLPWDKLGVDIVLECTGFFCSKTKSQAHIDAGAKRVLIS
CCCCEEEECCCCCEEECCCCCCCCHHHCCCEEEEEECCHHHHCCCCCHHHCCCCCEEEEE
APAGNDLPTIVYGVNHHTLKYDDLIVSGASCTTNCLAPLAKTLNDYRELRTGFMTTIHAY
CCCCCCCCEEEEECCCCEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
TGDQMLLDGPHRKGDFRRARAGAINIVPNSTGAAKAIGLVIPELDGKLIGSAQRVPVPSG
CCCEEEECCCCCCCCHHHHCCCEEEEEECCCCCHHEEEEEEECCCCCEECCCCCCCCCCC
SITILDATLKDETETVSVEGINEAMKRAADDSFGYSDEELVSSDIIGISYGSLFDSTQTL
CEEEEEEEECCCCCEEEECCHHHHHHHHCCCCCCCCHHHHHHHCEEEEECHHHHHHHHHH
AQRCGTKIYEVRVVSWYDNEMSYVSQLIRTLGLMGSLMR
HHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10463150; 11466286 [H]