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The map label for this gene is nuoG [H]

Identifier: 118579073

GI number: 118579073

Start: 670080

End: 671486

Strand: Direct

Name: nuoG [H]

Synonym: Ppro_0634

Alternate gene names: 118579073

Gene position: 670080-671486 (Clockwise)

Preceding gene: 118579072

Following gene: 118579074

Centisome position: 16.72

GC content: 62.26

Gene sequence:

>1407_bases
ATGATTGAACTAAAGATCGACAACCAAGTCATCGAGACGCAGGAAGGCGAAACCGTAATGGAAGCGGCGCTCAGGCACGG
CATCCATATTCCCCACCTCTGCTATCACCCCTGCCTCTCCATCGCCGGTAACTGCCGCATCTGCCTGGTGCAGGTCAACG
GTCGTCCCAAACTCATGCCGGCCTGCAACCTGCCCATCACCCCGGGAATGGAGATCGAAACGGACAGCGAACCGGTTCGG
GCCGCCCGGCGTGCCGTCATGCAGTTCATCACCTTAAACCACCCGGTGGACTGCGGCATCTGCGACAAGGCGGGCGAGTG
CCGGCTGCAGGAATACCAGATGAAGTACGGGGCGGATGAACCGTTCAACATCGATGCCAAGCACCACAAGCCCAAGTTCT
ACGACCTCTCCGACAGGATCGTCTACGACGCCGAGCGCTGCATCCTCTGCAGCCGCTGCGTGCGCTTCACCCGCGAAGTC
TCCGGCTCCTTCCAGTTGGGCATCGTCGAGCGGGGCAGCCACTCCCGGGTCGAGCGCCTGGACCAGGGGACCTTCGACGA
CCCCTACTCGGACAACGTCACCACCATCTGTCCCGTGGGAGCGCTCCTCTCCCGCGACTTCCTCTACAAGAGCCGGGTCT
GGTACCTGGAGCCGGTTCGTTCCGTCTGTCCCGGCTGCGCCAGGGGCTGCAGCATCAACATCTGGAAACGGGCCCACCAC
TGGCATCTGCGCGCCCTGGGCGAAGAGAAAAACCGCATGGTCTATAGGGTCACGCCGTGCGACAACCCGGAGATCAACGG
TCCCTGGATCTGCAACAAAGGCTTCGACCTGCCCAAAGAACTCATGAAACGCCCCAGGGCGCTGCGTCCCCTGGTGCACG
GCGCCTTCGTCGGCCTGGAAGAAACCATCGGCGAAGCCAAACGGCTCATCTCCCAGGCATCGAGCCCGGCCATCCTGGTC
TCGGCGTGGGCCTCCAACGAAGAGCTGGCCGCCTTCAAACAGCACCTGGGCGAGCGCTTCACCGTCTACACCCGCCAGGA
CGCAGGCCCCGAGAAAGGGGAGATCGTCGAAGACAACGTCCTGATCAAGGGTGACAAGAACCCCAACAGCAGAGGCGTGG
CAGACCTGTTCGGTAGCCAGGCCTACAGCCAGGCCGGCCACGACCTGGTCATCGTCTGGGGCGAAGGGGTCAGACTCTCC
GACCTGGGCAGCGCCACCGTCATCCAGCTGTCCTCCTTTGAGAACGCCCAGGACAAAAACGCCGACATCCTGATCCCCAT
CTCCACCTTCATGGAGCGGAGCGGGAGCTTCACCAACTTCGAAGGCACGGCGAACTGTTTTGACAAAGTGTTCGACAAAC
CGGAGCTGGTCCAGCATGCCGGCGAACTGTTCGGGAGGCTCGCATGA

Upstream 100 bases:

>100_bases
CCGGTCATAAACTTCATCACGAAATTCAGAGCGGAATTCGACTACTACATCGAACACGGTCGTTCCATGAACGACGGTCG
TTTGGAAATCTGAAGGCGCC

Downstream 100 bases:

>100_bases
TACAGGACCTGATCGTCTACCTCATCTTCATGGGCTACGCCATCGCCGTCATGGCCGGCGTCGCCACCATCTTCACCTGG
GTGGAGCGCAAGCAGTCGGC

Product: ferredoxin

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MIELKIDNQVIETQEGETVMEAALRHGIHIPHLCYHPCLSIAGNCRICLVQVNGRPKLMPACNLPITPGMEIETDSEPVR
AARRAVMQFITLNHPVDCGICDKAGECRLQEYQMKYGADEPFNIDAKHHKPKFYDLSDRIVYDAERCILCSRCVRFTREV
SGSFQLGIVERGSHSRVERLDQGTFDDPYSDNVTTICPVGALLSRDFLYKSRVWYLEPVRSVCPGCARGCSINIWKRAHH
WHLRALGEEKNRMVYRVTPCDNPEINGPWICNKGFDLPKELMKRPRALRPLVHGAFVGLEETIGEAKRLISQASSPAILV
SAWASNEELAAFKQHLGERFTVYTRQDAGPEKGEIVEDNVLIKGDKNPNSRGVADLFGSQAYSQAGHDLVIVWGEGVRLS
DLGSATVIQLSSFENAQDKNADILIPISTFMERSGSFTNFEGTANCFDKVFDKPELVQHAGELFGRLA

Sequences:

>Translated_468_residues
MIELKIDNQVIETQEGETVMEAALRHGIHIPHLCYHPCLSIAGNCRICLVQVNGRPKLMPACNLPITPGMEIETDSEPVR
AARRAVMQFITLNHPVDCGICDKAGECRLQEYQMKYGADEPFNIDAKHHKPKFYDLSDRIVYDAERCILCSRCVRFTREV
SGSFQLGIVERGSHSRVERLDQGTFDDPYSDNVTTICPVGALLSRDFLYKSRVWYLEPVRSVCPGCARGCSINIWKRAHH
WHLRALGEEKNRMVYRVTPCDNPEINGPWICNKGFDLPKELMKRPRALRPLVHGAFVGLEETIGEAKRLISQASSPAILV
SAWASNEELAAFKQHLGERFTVYTRQDAGPEKGEIVEDNVLIKGDKNPNSRGVADLFGSQAYSQAGHDLVIVWGEGVRLS
DLGSATVIQLSSFENAQDKNADILIPISTFMERSGSFTNFEGTANCFDKVFDKPELVQHAGELFGRLA
>Mature_468_residues
MIELKIDNQVIETQEGETVMEAALRHGIHIPHLCYHPCLSIAGNCRICLVQVNGRPKLMPACNLPITPGMEIETDSEPVR
AARRAVMQFITLNHPVDCGICDKAGECRLQEYQMKYGADEPFNIDAKHHKPKFYDLSDRIVYDAERCILCSRCVRFTREV
SGSFQLGIVERGSHSRVERLDQGTFDDPYSDNVTTICPVGALLSRDFLYKSRVWYLEPVRSVCPGCARGCSINIWKRAHH
WHLRALGEEKNRMVYRVTPCDNPEINGPWICNKGFDLPKELMKRPRALRPLVHGAFVGLEETIGEAKRLISQASSPAILV
SAWASNEELAAFKQHLGERFTVYTRQDAGPEKGEIVEDNVLIKGDKNPNSRGVADLFGSQAYSQAGHDLVIVWGEGVRLS
DLGSATVIQLSSFENAQDKNADILIPISTFMERSGSFTNFEGTANCFDKVFDKPELVQHAGELFGRLA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=343, Percent_Identity=32.6530612244898, Blast_Score=191, Evalue=1e-48,
Organism=Escherichia coli, GI145693161, Length=338, Percent_Identity=27.5147928994083, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32566231, Length=297, Percent_Identity=35.016835016835, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17565758, Length=297, Percent_Identity=35.016835016835, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI193209088, Length=240, Percent_Identity=36.6666666666667, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640559, Length=295, Percent_Identity=34.5762711864407, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24640557, Length=295, Percent_Identity=34.5762711864407, Blast_Score=193, Evalue=2e-49,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52376; Mature: 52376

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELKIDNQVIETQEGETVMEAALRHGIHIPHLCYHPCLSIAGNCRICLVQVNGRPKLMP
CEEEEECCCEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCE
ACNLPITPGMEIETDSEPVRAARRAVMQFITLNHPVDCGICDKAGECRLQEYQMKYGADE
ECCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
PFNIDAKHHKPKFYDLSDRIVYDAERCILCSRCVRFTREVSGSFQLGIVERGSHSRVERL
CCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHH
DQGTFDDPYSDNVTTICPVGALLSRDFLYKSRVWYLEPVRSVCPGCARGCSINIWKRAHH
CCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCEEECCHHHHCCHHHCCCEEEEEHHCCC
WHLRALGEEKNRMVYRVTPCDNPEINGPWICNKGFDLPKELMKRPRALRPLVHGAFVGLE
EEEEECCCCCCCEEEEECCCCCCCCCCCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHH
ETIGEAKRLISQASSPAILVSAWASNEELAAFKQHLGERFTVYTRQDAGPEKGEIVEDNV
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCE
LIKGDKNPNSRGVADLFGSQAYSQAGHDLVIVWGEGVRLSDLGSATVIQLSSFENAQDKN
EEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCEEEEEEECCCCCCCCC
ADILIPISTFMERSGSFTNFEGTANCFDKVFDKPELVQHAGELFGRLA
CEEEEEHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIELKIDNQVIETQEGETVMEAALRHGIHIPHLCYHPCLSIAGNCRICLVQVNGRPKLMP
CEEEEECCCEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCE
ACNLPITPGMEIETDSEPVRAARRAVMQFITLNHPVDCGICDKAGECRLQEYQMKYGADE
ECCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
PFNIDAKHHKPKFYDLSDRIVYDAERCILCSRCVRFTREVSGSFQLGIVERGSHSRVERL
CCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHH
DQGTFDDPYSDNVTTICPVGALLSRDFLYKSRVWYLEPVRSVCPGCARGCSINIWKRAHH
CCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCEEECCHHHHCCHHHCCCEEEEEHHCCC
WHLRALGEEKNRMVYRVTPCDNPEINGPWICNKGFDLPKELMKRPRALRPLVHGAFVGLE
EEEEECCCCCCCEEEEECCCCCCCCCCCEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHH
ETIGEAKRLISQASSPAILVSAWASNEELAAFKQHLGERFTVYTRQDAGPEKGEIVEDNV
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCE
LIKGDKNPNSRGVADLFGSQAYSQAGHDLVIVWGEGVRLSDLGSATVIQLSSFENAQDKN
EEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCEEEEEEECCCCCCCCC
ADILIPISTFMERSGSFTNFEGTANCFDKVFDKPELVQHAGELFGRLA
CEEEEEHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA