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The map label for this gene is nuoH [H]

Identifier: 118579074

GI number: 118579074

Start: 671483

End: 672652

Strand: Direct

Name: nuoH [H]

Synonym: Ppro_0635

Alternate gene names: 118579074

Gene position: 671483-672652 (Clockwise)

Preceding gene: 118579073

Following gene: 118579075

Centisome position: 16.75

GC content: 60.51

Gene sequence:

>1170_bases
ATGATACAGGACCTGATCGTCTACCTCATCTTCATGGGCTACGCCATCGCCGTCATGGCCGGCGTCGCCACCATCTTCAC
CTGGGTGGAGCGCAAGCAGTCGGCCATCATGGCCGACCGCATCGGCGCCAACCGCTGCTACCTGCGCATCCCCTTCACCA
ACGTCAAGATCGTTGCCTGGGGCCTCATCCACGGTATCGCCGACGGCAGCAAGATGCTCTTAAAGGAGAACTTCACCCCC
ACCACCTACGACCGCTTCTGCTACAACCTGGCCCCCTGGCTGGCCCTCGCCCCGGTGCTCCTGGTCTTCTCCGCCATCCC
CTTCGGCGGGACGCTTGTCCCGGGCAAACTGATCGACCCGGCCAGCTTCCCCCAGCTCTCCCAGATCATGGTCAACTTCT
TCGGGGACAAGAGCTATGTCATGCAGGTAGCCCGACTTGACGCCGGCATCCTGGTGATCCTGGCCATCTCCGGCATCGGC
ATCCTGGGCACCATGCTGGCCGGCTGGTCCTCCAACAACAAATTCTCCCTGCTGGGCGCCGCCCGCGCCGCCTCGCAGAT
GATCTCCTACGAAGTCTCCATGGGTCTGGCTTTAATCAGCCTGGTGGTCACCTACGGCACCCTGGATCTCAACGACATGG
TGGTCTGGCAGTCGGGCCTGCTCTTCGGCGTACTTCCCGCCTGGGGCATCATCCTGCAGCCCCTGGCCTTTGTGCTGTTC
CTCACCGCCTGCATCGCCGAGAACAAACGCGTCCCCTTCGACCTTCCGGAATGTGAATCGGAACTGGTTTCCGGCTACTT
CACCGAATACACCGCCATGAAGATGGGTATCTTCATGCTCAGTGAATTCATCGAGATCGTCGTCGTCTCGGCGCTTCTGG
TCACCGTCTTTCTGGGCGGCTACAACCTGCCGTACTTAACCGACGCCGGGTTCGTGCTCCCCATGGGCAAAACCATCGCC
CTGTCCCATGCAACTGTTGTCCTTGTGCAGATAGTCACCTTCCTGGTGAAGGTATTCCTGATCGGCTGCTTCCAGATCCA
GATTCGCTGGTCCGTGCCCCGTTTCCGCTATGACCAGCTCATGCGATTCGGCTGGAAGTTCCTGCTTCCCCTGGCCGCCC
TGAACCTCGTTGCCACGGCATGTGTCCGCTGGTTCACGCTGAAAGGATGA

Upstream 100 bases:

>100_bases
GGAGCTTCACCAACTTCGAAGGCACGGCGAACTGTTTTGACAAAGTGTTCGACAAACCGGAGCTGGTCCAGCATGCCGGC
GAACTGTTCGGGAGGCTCGC

Downstream 100 bases:

>100_bases
TATGAAGAAAGAGTACTGGAATAAGCCAACCATGGATCTGTGGGATCGCCTCTACATCTTCGAGGTGATCCGCGGGCTCT
GCATCACCGGATCGGTCTTC

Product: respiratory-chain NADH dehydrogenase, subunit 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MIQDLIVYLIFMGYAIAVMAGVATIFTWVERKQSAIMADRIGANRCYLRIPFTNVKIVAWGLIHGIADGSKMLLKENFTP
TTYDRFCYNLAPWLALAPVLLVFSAIPFGGTLVPGKLIDPASFPQLSQIMVNFFGDKSYVMQVARLDAGILVILAISGIG
ILGTMLAGWSSNNKFSLLGAARAASQMISYEVSMGLALISLVVTYGTLDLNDMVVWQSGLLFGVLPAWGIILQPLAFVLF
LTACIAENKRVPFDLPECESELVSGYFTEYTAMKMGIFMLSEFIEIVVVSALLVTVFLGGYNLPYLTDAGFVLPMGKTIA
LSHATVVLVQIVTFLVKVFLIGCFQIQIRWSVPRFRYDQLMRFGWKFLLPLAALNLVATACVRWFTLKG

Sequences:

>Translated_389_residues
MIQDLIVYLIFMGYAIAVMAGVATIFTWVERKQSAIMADRIGANRCYLRIPFTNVKIVAWGLIHGIADGSKMLLKENFTP
TTYDRFCYNLAPWLALAPVLLVFSAIPFGGTLVPGKLIDPASFPQLSQIMVNFFGDKSYVMQVARLDAGILVILAISGIG
ILGTMLAGWSSNNKFSLLGAARAASQMISYEVSMGLALISLVVTYGTLDLNDMVVWQSGLLFGVLPAWGIILQPLAFVLF
LTACIAENKRVPFDLPECESELVSGYFTEYTAMKMGIFMLSEFIEIVVVSALLVTVFLGGYNLPYLTDAGFVLPMGKTIA
LSHATVVLVQIVTFLVKVFLIGCFQIQIRWSVPRFRYDQLMRFGWKFLLPLAALNLVATACVRWFTLKG
>Mature_389_residues
MIQDLIVYLIFMGYAIAVMAGVATIFTWVERKQSAIMADRIGANRCYLRIPFTNVKIVAWGLIHGIADGSKMLLKENFTP
TTYDRFCYNLAPWLALAPVLLVFSAIPFGGTLVPGKLIDPASFPQLSQIMVNFFGDKSYVMQVARLDAGILVILAISGIG
ILGTMLAGWSSNNKFSLLGAARAASQMISYEVSMGLALISLVVTYGTLDLNDMVVWQSGLLFGVLPAWGIILQPLAFVLF
LTACIAENKRVPFDLPECESELVSGYFTEYTAMKMGIFMLSEFIEIVVVSALLVTVFLGGYNLPYLTDAGFVLPMGKTIA
LSHATVVLVQIVTFLVKVFLIGCFQIQIRWSVPRFRYDQLMRFGWKFLLPLAALNLVATACVRWFTLKG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=345, Percent_Identity=30.1449275362319, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1788618, Length=354, Percent_Identity=36.7231638418079, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 42905; Mature: 42905

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQDLIVYLIFMGYAIAVMAGVATIFTWVERKQSAIMADRIGANRCYLRIPFTNVKIVAW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
GLIHGIADGSKMLLKENFTPTTYDRFCYNLAPWLALAPVLLVFSAIPFGGTLVPGKLIDP
HHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ASFPQLSQIMVNFFGDKSYVMQVARLDAGILVILAISGIGILGTMLAGWSSNNKFSLLGA
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHH
ARAASQMISYEVSMGLALISLVVTYGTLDLNDMVVWQSGLLFGVLPAWGIILQPLAFVLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LTACIAENKRVPFDLPECESELVSGYFTEYTAMKMGIFMLSEFIEIVVVSALLVTVFLGG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YNLPYLTDAGFVLPMGKTIALSHATVVLVQIVTFLVKVFLIGCFQIQIRWSVPRFRYDQL
CCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHH
MRFGWKFLLPLAALNLVATACVRWFTLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQDLIVYLIFMGYAIAVMAGVATIFTWVERKQSAIMADRIGANRCYLRIPFTNVKIVAW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
GLIHGIADGSKMLLKENFTPTTYDRFCYNLAPWLALAPVLLVFSAIPFGGTLVPGKLIDP
HHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ASFPQLSQIMVNFFGDKSYVMQVARLDAGILVILAISGIGILGTMLAGWSSNNKFSLLGA
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHH
ARAASQMISYEVSMGLALISLVVTYGTLDLNDMVVWQSGLLFGVLPAWGIILQPLAFVLF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LTACIAENKRVPFDLPECESELVSGYFTEYTAMKMGIFMLSEFIEIVVVSALLVTVFLGG
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YNLPYLTDAGFVLPMGKTIALSHATVVLVQIVTFLVKVFLIGCFQIQIRWSVPRFRYDQL
CCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHH
MRFGWKFLLPLAALNLVATACVRWFTLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA