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The map label for this gene is nuoD1

Identifier: 118579070

GI number: 118579070

Start: 667120

End: 668331

Strand: Direct

Name: nuoD1

Synonym: Ppro_0631

Alternate gene names: 118579070

Gene position: 667120-668331 (Clockwise)

Preceding gene: 118579069

Following gene: 118579071

Centisome position: 16.64

GC content: 59.24

Gene sequence:

>1212_bases
GTGGAATACAAATCCCCGGTACGATCAAACCTGGAACAGACCGCCGACCCGAACCATGTTCTGGTCAACATGGGTCCCTC
CCATCCGGCCACCCACGGCACCATACAGATCATCGCCGCCCTGGACGGAGAGAGAGTCGCCAAAGCCGACATCCACTGCG
GCTACCTGCACCGTGGCTTCGAGAAGGAATCGGAGCACCACACCTACCACAAGATCATCCCCTTCACCGACCGTTTGAAC
TACTGCTCGGCCCTGAACAACAACTTCGCCTACGTGGAAGGTGTGGAGAAACTCTTAGGCATCGAACTCACGCCGCGCTG
CATCTACCTGCGCACGCTCCTGGCCGAATACAACCGGGTCGCCGACCACGTCACCTGCGTTGCTGCCACTGTCATGGAAA
TGGGCGCCATGACCGCGTTTTTGTACCTGATGACCATCCGCGACTATATCTTCGAGCACTTGAATCAGCTCACCGGCGCG
CGCCTCACCTACTCCTTTGCCCGTGTCGGCGGCTTAAAGAACGACCTGCCCGACGGCTGGCTGGAGCGGCTGGAAGAGAT
CCTGCAGTTCACCGAGAAGTACTGCGGCCGCATCCACGGGCTTCTGGACCGTAACCGCATCTTCATCGACCGTACCCGCG
ACGTGGGCGCCATGAGTCCCGAGCACGCGCTCAACTGGGGCTACACCGGCCCGATCCTGCGCTCCACCGGCGCCAAGATC
GACATCAGGAAAGACAACCCGTATCTCGCCTATGCCGACCTTGACTTCGAAGTCCCCGTCGGTATCAAGGGGGACAACTA
CGACCGTTACTACGTGCGCATGCGCGAGATCGACGAATCAATCTCCATGGTCAGGCAGTGCATGAAGAAACTTCCCGACG
GCCCGGTCAACATCGACGACCGCCGGATCATGTATCCCACCAAAGACAAGGTCTACACCAAGATCGAATACCTGATCAGC
CACTTCAAACTGGTCATCGACGGCATCCAGGTACCTGCCGGCGAAATCTACGTAAGCCACGAAGCGCCCAACGGCGAGCT
CGGCTTCTACCTGATCAGCGACGGCAGCGGCCGTCCCTACAAACTGCATGTCAGAAGTCCCAGCTTCGCGCACATGGGTG
GCATGCACACCCTGCTGGAGGGATATCAAGTCGCCGACGTCATCGCCACCTTCGGCTCCATGAACATGATCGGCGGGGAG
TGTGACCGATGA

Upstream 100 bases:

>100_bases
GATCCTTTTGTACGAAGGGTTCGAAGGCCATCCCCTGCGTAAAGACTACCCCATCGACAGGGAACAACCCATCGTCGAAT
ATCGGAAATAGGTGAACAGC

Downstream 100 bases:

>100_bases
GCTGTATAGAAGAGAAATTCGCCCAATTGCGCGCCACCTACCCCAAGGAGCTGAACTCCTCCCTGGTCATGCCTTTCTTA
AGGATCATGCTGGACGAGAA

Product: NADH dehydrogenase (ubiquinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MEYKSPVRSNLEQTADPNHVLVNMGPSHPATHGTIQIIAALDGERVAKADIHCGYLHRGFEKESEHHTYHKIIPFTDRLN
YCSALNNNFAYVEGVEKLLGIELTPRCIYLRTLLAEYNRVADHVTCVAATVMEMGAMTAFLYLMTIRDYIFEHLNQLTGA
RLTYSFARVGGLKNDLPDGWLERLEEILQFTEKYCGRIHGLLDRNRIFIDRTRDVGAMSPEHALNWGYTGPILRSTGAKI
DIRKDNPYLAYADLDFEVPVGIKGDNYDRYYVRMREIDESISMVRQCMKKLPDGPVNIDDRRIMYPTKDKVYTKIEYLIS
HFKLVIDGIQVPAGEIYVSHEAPNGELGFYLISDGSGRPYKLHVRSPSFAHMGGMHTLLEGYQVADVIATFGSMNMIGGE
CDR

Sequences:

>Translated_403_residues
MEYKSPVRSNLEQTADPNHVLVNMGPSHPATHGTIQIIAALDGERVAKADIHCGYLHRGFEKESEHHTYHKIIPFTDRLN
YCSALNNNFAYVEGVEKLLGIELTPRCIYLRTLLAEYNRVADHVTCVAATVMEMGAMTAFLYLMTIRDYIFEHLNQLTGA
RLTYSFARVGGLKNDLPDGWLERLEEILQFTEKYCGRIHGLLDRNRIFIDRTRDVGAMSPEHALNWGYTGPILRSTGAKI
DIRKDNPYLAYADLDFEVPVGIKGDNYDRYYVRMREIDESISMVRQCMKKLPDGPVNIDDRRIMYPTKDKVYTKIEYLIS
HFKLVIDGIQVPAGEIYVSHEAPNGELGFYLISDGSGRPYKLHVRSPSFAHMGGMHTLLEGYQVADVIATFGSMNMIGGE
CDR
>Mature_403_residues
MEYKSPVRSNLEQTADPNHVLVNMGPSHPATHGTIQIIAALDGERVAKADIHCGYLHRGFEKESEHHTYHKIIPFTDRLN
YCSALNNNFAYVEGVEKLLGIELTPRCIYLRTLLAEYNRVADHVTCVAATVMEMGAMTAFLYLMTIRDYIFEHLNQLTGA
RLTYSFARVGGLKNDLPDGWLERLEEILQFTEKYCGRIHGLLDRNRIFIDRTRDVGAMSPEHALNWGYTGPILRSTGAKI
DIRKDNPYLAYADLDFEVPVGIKGDNYDRYYVRMREIDESISMVRQCMKKLPDGPVNIDDRRIMYPTKDKVYTKIEYLIS
HFKLVIDGIQVPAGEIYVSHEAPNGELGFYLISDGSGRPYKLHVRSPSFAHMGGMHTLLEGYQVADVIATFGSMNMIGGE
CDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=406, Percent_Identity=40.1477832512315, Blast_Score=339, Evalue=3e-93,
Organism=Homo sapiens, GI260898743, Length=400, Percent_Identity=39.75, Blast_Score=330, Evalue=1e-90,
Organism=Escherichia coli, GI145693162, Length=391, Percent_Identity=36.0613810741688, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1789076, Length=394, Percent_Identity=23.8578680203046, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788832, Length=385, Percent_Identity=23.1168831168831, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17568379, Length=408, Percent_Identity=39.7058823529412, Blast_Score=350, Evalue=9e-97,
Organism=Caenorhabditis elegans, GI17555284, Length=410, Percent_Identity=40, Blast_Score=348, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24638644, Length=388, Percent_Identity=40.979381443299, Blast_Score=343, Evalue=9e-95,
Organism=Drosophila melanogaster, GI221459469, Length=384, Percent_Identity=42.4479166666667, Blast_Score=336, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_PELPD (A1ALP2)

Other databases:

- EMBL:   CP000482
- EMBL:   CP000482
- EMBL:   CP000482
- RefSeq:   YP_900320.1
- RefSeq:   YP_901299.1
- RefSeq:   YP_902841.1
- ProteinModelPortal:   A1ALP2
- SMR:   A1ALP2
- STRING:   A1ALP2
- GeneID:   4571843
- GeneID:   4571936
- GeneID:   4573257
- GenomeReviews:   CP000482_GR
- GenomeReviews:   CP000482_GR
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0631
- KEGG:   ppd:Ppro_1626
- KEGG:   ppd:Ppro_3190
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   THPATHG
- PhylomeDB:   A1ALP2
- ProtClustDB:   CLSK961783
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR001135
- InterPro:   IPR022885

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 45754; Mature: 45754

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKSPVRSNLEQTADPNHVLVNMGPSHPATHGTIQIIAALDGERVAKADIHCGYLHRGF
CCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEHHCCEEHHHHCCC
EKESEHHTYHKIIPFTDRLNYCSALNNNFAYVEGVEKLLGIELTPRCIYLRTLLAEYNRV
CCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ADHVTCVAATVMEMGAMTAFLYLMTIRDYIFEHLNQLTGARLTYSFARVGGLKNDLPDGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
LERLEEILQFTEKYCGRIHGLLDRNRIFIDRTRDVGAMSPEHALNWGYTGPILRSTGAKI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCEE
DIRKDNPYLAYADLDFEVPVGIKGDNYDRYYVRMREIDESISMVRQCMKKLPDGPVNIDD
EEECCCCEEEEEECCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RRIMYPTKDKVYTKIEYLISHFKLVIDGIQVPAGEIYVSHEAPNGELGFYLISDGSGRPY
CEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCE
KLHVRSPSFAHMGGMHTLLEGYQVADVIATFGSMNMIGGECDR
EEEECCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEYKSPVRSNLEQTADPNHVLVNMGPSHPATHGTIQIIAALDGERVAKADIHCGYLHRGF
CCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEHHCCEEHHHHCCC
EKESEHHTYHKIIPFTDRLNYCSALNNNFAYVEGVEKLLGIELTPRCIYLRTLLAEYNRV
CCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ADHVTCVAATVMEMGAMTAFLYLMTIRDYIFEHLNQLTGARLTYSFARVGGLKNDLPDGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
LERLEEILQFTEKYCGRIHGLLDRNRIFIDRTRDVGAMSPEHALNWGYTGPILRSTGAKI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCEE
DIRKDNPYLAYADLDFEVPVGIKGDNYDRYYVRMREIDESISMVRQCMKKLPDGPVNIDD
EEECCCCEEEEEECCEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RRIMYPTKDKVYTKIEYLISHFKLVIDGIQVPAGEIYVSHEAPNGELGFYLISDGSGRPY
CEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCE
KLHVRSPSFAHMGGMHTLLEGYQVADVIATFGSMNMIGGECDR
EEEECCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA