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The map label for this gene is nuoC [H]

Identifier: 118579069

GI number: 118579069

Start: 666646

End: 667110

Strand: Direct

Name: nuoC [H]

Synonym: Ppro_0630

Alternate gene names: 118579069

Gene position: 666646-667110 (Clockwise)

Preceding gene: 118579068

Following gene: 118579070

Centisome position: 16.63

GC content: 58.71

Gene sequence:

>465_bases
ATGGTCAACGAGACAATACGCACCACCGTCAGTGAGTTGTACGATCGATCCTGGGACAGTCACGGCATGCTGGTCCTTGA
GACCGACGCCGGCCGTATCCTTCCCCTGATCACCCGCCTGAAGCGCTCCTTCTACTTCGATCTTCTTCTGGACATAACCG
GCGTGGACTATCCCGAGCGGGACCCTCGCTTCGACGTCGTCTACCACCTGTACAGCCCGCGCAACAACGTGCGGGTCAGG
ATCAAGGTACCGGTCACGGAAGCCGAGCCCAACGTCCCGACCCTAACCGGCCTGTACGGTTCGGCCCGCTACATCGAGCG
CGAAGTGCACGAGATGTACGGCATCGTCTCCATCGGCAACGACGACCTTCGTCCGATCCTTTTGTACGAAGGGTTCGAAG
GCCATCCCCTGCGTAAAGACTACCCCATCGACAGGGAACAACCCATCGTCGAATATCGGAAATAG

Upstream 100 bases:

>100_bases
TCGTGACTTCGTGTGCGTAATTGTTTTACCCGGTTAAACGGATCCGCGTTCCATTTTGCTTTTGTGAAGTCATTCTTTCC
TGACAGTAAGAGAGAACTCC

Downstream 100 bases:

>100_bases
GTGAACAGCGTGGAATACAAATCCCCGGTACGATCAAACCTGGAACAGACCGCCGACCCGAACCATGTTCTGGTCAACAT
GGGTCCCTCCCATCCGGCCA

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVNETIRTTVSELYDRSWDSHGMLVLETDAGRILPLITRLKRSFYFDLLLDITGVDYPERDPRFDVVYHLYSPRNNVRVR
IKVPVTEAEPNVPTLTGLYGSARYIEREVHEMYGIVSIGNDDLRPILLYEGFEGHPLRKDYPIDREQPIVEYRK

Sequences:

>Translated_154_residues
MVNETIRTTVSELYDRSWDSHGMLVLETDAGRILPLITRLKRSFYFDLLLDITGVDYPERDPRFDVVYHLYSPRNNVRVR
IKVPVTEAEPNVPTLTGLYGSARYIEREVHEMYGIVSIGNDDLRPILLYEGFEGHPLRKDYPIDREQPIVEYRK
>Mature_154_residues
MVNETIRTTVSELYDRSWDSHGMLVLETDAGRILPLITRLKRSFYFDLLLDITGVDYPERDPRFDVVYHLYSPRNNVRVR
IKVPVTEAEPNVPTLTGLYGSARYIEREVHEMYGIVSIGNDDLRPILLYEGFEGHPLRKDYPIDREQPIVEYRK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=114, Percent_Identity=39.4736842105263, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI145693162, Length=102, Percent_Identity=39.2156862745098, Blast_Score=73, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71990788, Length=113, Percent_Identity=44.2477876106195, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32563621, Length=114, Percent_Identity=43.859649122807, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24656494, Length=113, Percent_Identity=41.5929203539823, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18058; Mature: 18058

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNETIRTTVSELYDRSWDSHGMLVLETDAGRILPLITRLKRSFYFDLLLDITGVDYPER
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCC
DPRFDVVYHLYSPRNNVRVRIKVPVTEAEPNVPTLTGLYGSARYIEREVHEMYGIVSIGN
CCCEEEEEEEECCCCCEEEEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCEEEECC
DDLRPILLYEGFEGHPLRKDYPIDREQPIVEYRK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVNETIRTTVSELYDRSWDSHGMLVLETDAGRILPLITRLKRSFYFDLLLDITGVDYPER
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCC
DPRFDVVYHLYSPRNNVRVRIKVPVTEAEPNVPTLTGLYGSARYIEREVHEMYGIVSIGN
CCCEEEEEEEECCCCCEEEEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCEEEECC
DDLRPILLYEGFEGHPLRKDYPIDREQPIVEYRK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA