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The map label for this gene is yqjC [H]

Identifier: 118578961

GI number: 118578961

Start: 554446

End: 554850

Strand: Reverse

Name: yqjC [H]

Synonym: Ppro_0522

Alternate gene names: 118578961

Gene position: 554850-554446 (Counterclockwise)

Preceding gene: 118578962

Following gene: 118578960

Centisome position: 13.84

GC content: 60.25

Gene sequence:

>405_bases
ATGCTCAAGAAGATCAACCACATCGGCATTGCAGTAAAATCACTGGAAGAAGCCCTTCCCTTCTACCGCGACAACCTGGC
CATGCCCTTCGCCGGCATCGAAGAAGTTGCCGAGCAGAAAGTGCGCGTAGCCATGCTGCAGATCGGCGAATCCAAGATCG
AGCTTTTGGAGCCGACCAGCGAAGACAGCCCCATCGCCAAGTTCCTGGAAAAGAACGGCTCCGGCGTGCATCACCTGGCC
TATGAAGTTGACGACTGCGCCGCCGCCATCGCCAAGATGGTAGCCGACGGCGCCCGCATGATCGACAGCGCACCCCGCAA
CGGCGCCCACGGCACCAAGATCGCCTTCGTGCACCCCAAGAGCAGCAACGGCATCCTGACCGAACTGTGCCAGTGCGGCC
ACTGA

Upstream 100 bases:

>100_bases
GGAAACCGTCGTCCTGTAATTCATAACCAGCAGTCAAACTTCACAGGGCCAGGCCGATCAAGCCTGGCCCTGTGCTGATT
CCCAAGAAAGGTGACATGAA

Downstream 100 bases:

>100_bases
CGGAGTCTGTTGGTTCCGATTAAGCACAATATAAAAAGGCGAAGCACGTCGCATGCTTCGCCTTTTTTTTAAGTCCGTTA
TAGAAATGTGCAGAGAACCG

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MLKKINHIGIAVKSLEEALPFYRDNLAMPFAGIEEVAEQKVRVAMLQIGESKIELLEPTSEDSPIAKFLEKNGSGVHHLA
YEVDDCAAAIAKMVADGARMIDSAPRNGAHGTKIAFVHPKSSNGILTELCQCGH

Sequences:

>Translated_134_residues
MLKKINHIGIAVKSLEEALPFYRDNLAMPFAGIEEVAEQKVRVAMLQIGESKIELLEPTSEDSPIAKFLEKNGSGVHHLA
YEVDDCAAAIAKMVADGARMIDSAPRNGAHGTKIAFVHPKSSNGILTELCQCGH
>Mature_134_residues
MLKKINHIGIAVKSLEEALPFYRDNLAMPFAGIEEVAEQKVRVAMLQIGESKIELLEPTSEDSPIAKFLEKNGSGVHHLA
YEVDDCAAAIAKMVADGARMIDSAPRNGAHGTKIAFVHPKSSNGILTELCQCGH

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=132, Percent_Identity=39.3939393939394, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17506387, Length=132, Percent_Identity=37.8787878787879, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14467; Mature: 14467

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKINHIGIAVKSLEEALPFYRDNLAMPFAGIEEVAEQKVRVAMLQIGESKIELLEPTS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEECCCC
EDSPIAKFLEKNGSGVHHLAYEVDDCAAAIAKMVADGARMIDSAPRNGAHGTKIAFVHPK
CCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
SSNGILTELCQCGH
CCCCHHHHHHHCCC
>Mature Secondary Structure
MLKKINHIGIAVKSLEEALPFYRDNLAMPFAGIEEVAEQKVRVAMLQIGESKIELLEPTS
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEECCCC
EDSPIAKFLEKNGSGVHHLAYEVDDCAAAIAKMVADGARMIDSAPRNGAHGTKIAFVHPK
CCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
SSNGILTELCQCGH
CCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]