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The map label for this gene is sdhA [H]

Identifier: 118478557

GI number: 118478557

Start: 3117543

End: 3118433

Strand: Reverse

Name: sdhA [H]

Synonym: BALH_2933

Alternate gene names: 118478557

Gene position: 3118433-3117543 (Counterclockwise)

Preceding gene: 118478558

Following gene: 118478556

Centisome position: 59.32

GC content: 39.17

Gene sequence:

>891_bases
ATGTATATGTCCATAAAAGAAATTGTGGATGCAGCTAATAAAAGCCAAAAGCCAATTTATGAATTAGCAATTGAACAGGA
AATGGAACAAACTAAATCTACTTATGAAGAAGTTTTGAATAAAATGGAACGAAATTTAGCGACTATGAAAAATGCTATAA
ATAAAAGTATTGAGGGCGACGGGGTATTTTCTCCGACTGGTTTAACTGGAGGGGATGCTGTTAAAATTAAAAATTATCGA
GAAAATAGGAAAACTCTTTCTGGAGATTTGATGGTGTTAGGGATCCAAAGTGCTATTGGTGTTAATGAAGTAAATGCTGC
ATTAGGAGCTATTTGTGCAACTCCAACAGCAGGTGCGAGTGGAACGATTCCGGGAGTTCTATTTAGTATTAAAGATACGT
TAGATTTAAGTCATGAAGATATGATTCATTTTCTATTCACTTCAGCGTTATTTGGAACAATAGTTGCAAACAATGCTTGT
ATATCAGGAGCGTACGGGGGATGTCAAGCTGAAATAGGAAGTGCCTCAGCGATGGCGGCTGCAGCTGCAGTAGAAGCTGC
GGGTGGAACGCCACAGCAATCTTCTGAAGCTTTTTCAATTGCGTTACAAAATTTACTCGGTTTAGTTTGTGATCCAGTCG
CTGGTTTGGTAGAAATTCCTTGTGTAAAGAGAAACGCCATTGGGACGGCAAATGCTTTAGCAGCAGGGGACATCGCATTA
GCCGGTGTAAACAATATCATCAATGCTGACGAAGTTATTGAAGCGATGTATAGAGTTGGAAGACAGATGCCTCGCGAATT
AAGAGAGACAGGTTTAGGTGGAATTGCGGCTACACCTACAGGGATTGCCATTAAAAATAAAATATTTGGGGAGAAACAAT
CAAATCAATGA

Upstream 100 bases:

>100_bases
TTAGATTCAATATTGCCTGTTAATATTCAGGAGGAGTTAAGAAATTTAAGCAATATAGCTAATCTTATTATTCTTTAGTT
ACATTAAGGAGTGAAAAAAT

Downstream 100 bases:

>100_bases
ACAGTTAACGTCTATATTGTGAAATAGTTAACAATCTATTCTCTATTGTTCGCTTAAGGATTTCTAGATATTGGGGAATT
ATCAATAATATATCCTACTA

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MYMSIKEIVDAANKSQKPIYELAIEQEMEQTKSTYEEVLNKMERNLATMKNAINKSIEGDGVFSPTGLTGGDAVKIKNYR
ENRKTLSGDLMVLGIQSAIGVNEVNAALGAICATPTAGASGTIPGVLFSIKDTLDLSHEDMIHFLFTSALFGTIVANNAC
ISGAYGGCQAEIGSASAMAAAAAVEAAGGTPQQSSEAFSIALQNLLGLVCDPVAGLVEIPCVKRNAIGTANALAAGDIAL
AGVNNIINADEVIEAMYRVGRQMPRELRETGLGGIAATPTGIAIKNKIFGEKQSNQ

Sequences:

>Translated_296_residues
MYMSIKEIVDAANKSQKPIYELAIEQEMEQTKSTYEEVLNKMERNLATMKNAINKSIEGDGVFSPTGLTGGDAVKIKNYR
ENRKTLSGDLMVLGIQSAIGVNEVNAALGAICATPTAGASGTIPGVLFSIKDTLDLSHEDMIHFLFTSALFGTIVANNAC
ISGAYGGCQAEIGSASAMAAAAAVEAAGGTPQQSSEAFSIALQNLLGLVCDPVAGLVEIPCVKRNAIGTANALAAGDIAL
AGVNNIINADEVIEAMYRVGRQMPRELRETGLGGIAATPTGIAIKNKIFGEKQSNQ
>Mature_296_residues
MYMSIKEIVDAANKSQKPIYELAIEQEMEQTKSTYEEVLNKMERNLATMKNAINKSIEGDGVFSPTGLTGGDAVKIKNYR
ENRKTLSGDLMVLGIQSAIGVNEVNAALGAICATPTAGASGTIPGVLFSIKDTLDLSHEDMIHFLFTSALFGTIVANNAC
ISGAYGGCQAEIGSASAMAAAAAVEAAGGTPQQSSEAFSIALQNLLGLVCDPVAGLVEIPCVKRNAIGTANALAAGDIAL
AGVNNIINADEVIEAMYRVGRQMPRELRETGLGGIAATPTGIAIKNKIFGEKQSNQ

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=281, Percent_Identity=34.1637010676157, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1789161, Length=263, Percent_Identity=35.361216730038, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI48994925, Length=238, Percent_Identity=36.9747899159664, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30829; Mature: 30829

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMSIKEIVDAANKSQKPIYELAIEQEMEQTKSTYEEVLNKMERNLATMKNAINKSIEGD
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVFSPTGLTGGDAVKIKNYRENRKTLSGDLMVLGIQSAIGVNEVNAALGAICATPTAGAS
CCCCCCCCCCCCEEEECCHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCCCC
GTIPGVLFSIKDTLDLSHEDMIHFLFTSALFGTIVANNACISGAYGGCQAEIGSASAMAA
CCCCHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHCCCCHHHHHH
AAAVEAAGGTPQQSSEAFSIALQNLLGLVCDPVAGLVEIPCVKRNAIGTANALAAGDIAL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHH
AGVNNIINADEVIEAMYRVGRQMPRELRETGLGGIAATPTGIAIKNKIFGEKQSNQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEHHHHCCCCCCCC
>Mature Secondary Structure
MYMSIKEIVDAANKSQKPIYELAIEQEMEQTKSTYEEVLNKMERNLATMKNAINKSIEGD
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVFSPTGLTGGDAVKIKNYRENRKTLSGDLMVLGIQSAIGVNEVNAALGAICATPTAGAS
CCCCCCCCCCCCEEEECCHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCCCCCC
GTIPGVLFSIKDTLDLSHEDMIHFLFTSALFGTIVANNACISGAYGGCQAEIGSASAMAA
CCCCHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHCCCCHHHHHH
AAAVEAAGGTPQQSSEAFSIALQNLLGLVCDPVAGLVEIPCVKRNAIGTANALAAGDIAL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHH
AGVNNIINADEVIEAMYRVGRQMPRELRETGLGGIAATPTGIAIKNKIFGEKQSNQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]