Click here to switch to the map view.

The map label for this gene is sdaC [H]

Identifier: 118478556

GI number: 118478556

Start: 3115931

End: 3117250

Strand: Reverse

Name: sdaC [H]

Synonym: BALH_2932

Alternate gene names: 118478556

Gene position: 3117250-3115931 (Counterclockwise)

Preceding gene: 118478557

Following gene: 118478555

Centisome position: 59.3

GC content: 35.61

Gene sequence:

>1320_bases
ATGAATGGGAATACTGCAAAAAACATAGAATTTCAAGCTGATAATACTAGAGGAAAAAATGAGAAATATCTAGACCCTAA
AAAGTGGAATAAACAAGATACTACCTGGGCATTGAGTCTATTTGGAACAGCAATTGGAGCAGGAGTACTCTTCTTACCGA
TTAATGCAGGTTCAGGTGGTTTATTATCGTTGCTGTTAATTACCATACTTGCATATCCTGTTATGTATTACTCACATAGG
GCGCTTGCAAAAATGATATACGCTTCGAATTCTGCCGAAGAGGGGATTACAGGTACAATAAGAGAGTATTTCGGAAATAA
AGCAAGTATTATTTTTAACATCGTATATTTCGTCTCCATTTATACGATCGTGCTGATGTATTCGGTTGCACTTACAAATA
CTGCAAGTAGTTTTATTGTACACCAATTGCACATGCCGGAGCCTCCAAGGGCTATTTTATCACTTGTATTAGTACTCGGT
CTTATCACTATACTAAATTTTGGTCAAGATATTACTGTAAAGATAATGAGCATGCTAGTATATCCTTTCATTGCTTCTCT
ACTTTTTATTGCAATATCTTTAATTCCACAATGGAATACTTCAATGCTAAGTTTTTCAAGTGTTTCTACTGCTTCAACTG
GAACAGGATATTTCGGAATGATTTGGATGATTCTACCAATCATCGTATTCTCGTTTAATCATTCTCCTATGATTTCGTCA
TTTGTTATGAAACAGAGAGCTACGTATGGAATAGATGCTACTGATGCCAAGTGTGCTCAAATACAAAAAGTTTGTTATAT
CATGACATTCGCTGTTGTTATGTTCTTTGTGTGGAGCAGTACTTTAAGTTTGACTCCAGATGATCTTAAGGTGGCGAAAG
AACAGAATTTGTCAATTCTATCATATCTTGCTAATGAGCTTAATTCGCCTGTAATCACGATTGCAGCTCCTATCATTGCG
TTTGTAGCTATTACAAAGTCTTTCCTTGGCCATTATATAGGAGCGTATGAGGTAATGCGTGACATGATTATTAAGTCCGG
TAAAAAACGTGGGAAAGATATAGGAGAAAAAACAGTTAAGGCAATGATTCTTACTTTTGTTGTACTAACATGCTGGTATG
TTGCTTATACAAATCCAAGTATTCTTGGAATCATTGATGCCCTTAGCGGTCCGTTAGTCGCTGCTATCTTATGTCTATTA
CCGATGTATGCGATTCGTAAAGTACCAGTACTAGCAAAATACAGAGGGAAAATGAGCAATGTATTTGTAATTATTATAGG
GATACTTACTGTTCTAGCAAGTATTAAGTCATTATTCTAA

Upstream 100 bases:

>100_bases
GATGTGGCGCACTTTATAAACAATTCATTTTTAAAGAACGGTCTATATTCCGATGCCTTAAATAGAGAAGTAAGAATAGG
ACACTAGGAGGAATTATTAT

Downstream 100 bases:

>100_bases
TTCACTATTGTTAGTTCTAATGCAAAAATAGTAGGATATGAAAAGAGAATAAAAGACTTTTAGCGGAACTGAAGTATATA
TTGTTTACCCAGAGAGATTA

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNGNTAKNIEFQADNTRGKNEKYLDPKKWNKQDTTWALSLFGTAIGAGVLFLPINAGSGGLLSLLLITILAYPVMYYSHR
ALAKMIYASNSAEEGITGTIREYFGNKASIIFNIVYFVSIYTIVLMYSVALTNTASSFIVHQLHMPEPPRAILSLVLVLG
LITILNFGQDITVKIMSMLVYPFIASLLFIAISLIPQWNTSMLSFSSVSTASTGTGYFGMIWMILPIIVFSFNHSPMISS
FVMKQRATYGIDATDAKCAQIQKVCYIMTFAVVMFFVWSSTLSLTPDDLKVAKEQNLSILSYLANELNSPVITIAAPIIA
FVAITKSFLGHYIGAYEVMRDMIIKSGKKRGKDIGEKTVKAMILTFVVLTCWYVAYTNPSILGIIDALSGPLVAAILCLL
PMYAIRKVPVLAKYRGKMSNVFVIIIGILTVLASIKSLF

Sequences:

>Translated_439_residues
MNGNTAKNIEFQADNTRGKNEKYLDPKKWNKQDTTWALSLFGTAIGAGVLFLPINAGSGGLLSLLLITILAYPVMYYSHR
ALAKMIYASNSAEEGITGTIREYFGNKASIIFNIVYFVSIYTIVLMYSVALTNTASSFIVHQLHMPEPPRAILSLVLVLG
LITILNFGQDITVKIMSMLVYPFIASLLFIAISLIPQWNTSMLSFSSVSTASTGTGYFGMIWMILPIIVFSFNHSPMISS
FVMKQRATYGIDATDAKCAQIQKVCYIMTFAVVMFFVWSSTLSLTPDDLKVAKEQNLSILSYLANELNSPVITIAAPIIA
FVAITKSFLGHYIGAYEVMRDMIIKSGKKRGKDIGEKTVKAMILTFVVLTCWYVAYTNPSILGIIDALSGPLVAAILCLL
PMYAIRKVPVLAKYRGKMSNVFVIIIGILTVLASIKSLF
>Mature_439_residues
MNGNTAKNIEFQADNTRGKNEKYLDPKKWNKQDTTWALSLFGTAIGAGVLFLPINAGSGGLLSLLLITILAYPVMYYSHR
ALAKMIYASNSAEEGITGTIREYFGNKASIIFNIVYFVSIYTIVLMYSVALTNTASSFIVHQLHMPEPPRAILSLVLVLG
LITILNFGQDITVKIMSMLVYPFIASLLFIAISLIPQWNTSMLSFSSVSTASTGTGYFGMIWMILPIIVFSFNHSPMISS
FVMKQRATYGIDATDAKCAQIQKVCYIMTFAVVMFFVWSSTLSLTPDDLKVAKEQNLSILSYLANELNSPVITIAAPIIA
FVAITKSFLGHYIGAYEVMRDMIIKSGKKRGKDIGEKTVKAMILTFVVLTCWYVAYTNPSILGIIDALSGPLVAAILCLL
PMYAIRKVPVLAKYRGKMSNVFVIIIGILTVLASIKSLF

Specific function: Involved in the import of serine into the cell. May be required for phage C1 adsorption by interacting with DrcB. May also be involved in ampicillin sensitivity [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=412, Percent_Identity=52.1844660194175, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789504, Length=430, Percent_Identity=44.6511627906977, Blast_Score=352, Evalue=2e-98,
Organism=Escherichia coli, GI1789211, Length=409, Percent_Identity=36.4303178484108, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI145693183, Length=423, Percent_Identity=25.7683215130024, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1789961, Length=408, Percent_Identity=24.7549019607843, Blast_Score=122, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 48315; Mature: 48315

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGNTAKNIEFQADNTRGKNEKYLDPKKWNKQDTTWALSLFGTAIGAGVLFLPINAGSGG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCH
LLSLLLITILAYPVMYYSHRALAKMIYASNSAEEGITGTIREYFGNKASIIFNIVYFVSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
YTIVLMYSVALTNTASSFIVHQLHMPEPPRAILSLVLVLGLITILNFGQDITVKIMSMLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YPFIASLLFIAISLIPQWNTSMLSFSSVSTASTGTGYFGMIWMILPIIVFSFNHSPMISS
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
FVMKQRATYGIDATDAKCAQIQKVCYIMTFAVVMFFVWSSTLSLTPDDLKVAKEQNLSIL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHH
SYLANELNSPVITIAAPIIAFVAITKSFLGHYIGAYEVMRDMIIKSGKKRGKDIGEKTVK
HHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHH
AMILTFVVLTCWYVAYTNPSILGIIDALSGPLVAAILCLLPMYAIRKVPVLAKYRGKMSN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHHH
VFVIIIGILTVLASIKSLF
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNGNTAKNIEFQADNTRGKNEKYLDPKKWNKQDTTWALSLFGTAIGAGVLFLPINAGSGG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCH
LLSLLLITILAYPVMYYSHRALAKMIYASNSAEEGITGTIREYFGNKASIIFNIVYFVSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
YTIVLMYSVALTNTASSFIVHQLHMPEPPRAILSLVLVLGLITILNFGQDITVKIMSMLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YPFIASLLFIAISLIPQWNTSMLSFSSVSTASTGTGYFGMIWMILPIIVFSFNHSPMISS
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
FVMKQRATYGIDATDAKCAQIQKVCYIMTFAVVMFFVWSSTLSLTPDDLKVAKEQNLSIL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHH
SYLANELNSPVITIAAPIIAFVAITKSFLGHYIGAYEVMRDMIIKSGKKRGKDIGEKTVK
HHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHH
AMILTFVVLTCWYVAYTNPSILGIIDALSGPLVAAILCLLPMYAIRKVPVLAKYRGKMSN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHHH
VFVIIIGILTVLASIKSLF
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]