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The map label for this gene is yoeA [H]

Identifier: 117922005

GI number: 117922005

Start: 4280766

End: 4282124

Strand: Direct

Name: yoeA [H]

Synonym: Shewana3_3569

Alternate gene names: 117922005

Gene position: 4280766-4282124 (Clockwise)

Preceding gene: 117922002

Following gene: 117922007

Centisome position: 86.09

GC content: 52.24

Gene sequence:

>1359_bases
ATGAAAGACAGACACGGGCTGCTTAGCGCGCCAATTGGTCGTGTACTGCTCAACATGAGCCTCCCCAACTTGATTGGCAT
TATGACCATTCTAGGTTTTAGCCTCGCTGACACTTTTTTTATCAGTCAGTTAGGGACCGAAGCCTTAGCGGCGATCAGTT
TTACCTTTCCGGTGACTTTGATTATTTCCAGCATCGCCATTGGGATTGGTGCCGGCGTTTCCACTAACCTTGGCAGGCTG
ATAGGCTCGGGCAATGCCCCACGCGCCAAGGTGTTTCTGCACGATGCGCTGCTGCTAACCTTTATCCTTATCGCCAGCTT
ATCCGCCCTAGGTAGCATTTTTATTAAGCCGCTCTTTAGTTTGCTTGGCGCCAATGACACCAGCTTGCCGCTGATCCACG
ACTATATGATGTATTGGTATGTGGGCGCGCCGCTGTTGGTGCTATTGATGGTGGGTAATCAAGGCCTGCGCTCGACTGGG
GATACTCGCTCCCCTGCGATGATTATGGCGCTGGCGGCGATCATTAACTTAATACTCGATCCCTTATTAATCTTCGGCAT
TGGGCCCTTCCCACGCTTGGAGATCCAAGGCGCGGCGATTGCAACCCTGTTCTCTTGGCTGATAGCCCTGTCGCTCTCGG
GTTATTTGTTGATTATTAAGCGCAATATGTTGGAATGGGCGGCATTTGATATCGATAGAATGCGCGCCAACTGGAGTAAA
CTCGCCCATATCGCCCAGCCCGCAGCTCTGATGAATTTAATCAACCCACTCGCCAATGCGGTGATTATGGCGATGCTGGC
GCATATCGACCACAGTGCCGTCGCGGCCTTTGGTGCGGGCACCCGTTTAGAATCTGTGCTCTTGATTGTGGTGATGGCGC
TCTCGTCGAGCCTGATGCCGTTTATCGCGCAAAACCTCGGGGCAGGCCAAACTCAAAGGGCGAAACAGGCGTTGCTGTTA
TCGCTTAAATTTATCTTTGTATTCCAAACCTTACTCTATATTCCGCTGGCATTTTTCGCCCAGCCACTTGCCCATTTATT
CAGTACCGATCCGCAGGTGCTAGAGTGGTTAAGTTTTTATATTCTGGTCTTGCCCTGCGCCTACGGCCCGCTCGGCATAG
TGATCATCTTTGCCACGGCACTGAATGCGTACCACAGACCCATGAGCTCGTTAGTGATTAACCTGTGCCGCTTAGTGCTG
CTGATGCTGCCGTTGGCGGCGCTGGGGTCTTATATCGATGGGGTGAAAGGCTTGTTGCTCGCGCTCCCCATCACCAACCT
CTTGATGGGGATTGCTTGTTATTATCTGGCGCAGCGCATTTGCGAACCCGCTAAGGTGACGACCGCCGACGCTATTTAA

Upstream 100 bases:

>100_bases
TTTACAAAAAAAAATTCAAATTTTTGATGTCAGTTTTTTCAAGCGGGCACAATCCTGCTAGAATTCGGCCTCCGCTCGCA
AACAAGGCACCATTTTCCCC

Downstream 100 bases:

>100_bases
GAAGTGCTTTTTTGGCGAAAGCGTAAATCATTTTGCAGGAAGGGTTCTTCGGAGGCCTTACAAACTCGGCGAGTGGCGAT
CCCCTCTTGACTCATATTGG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKDRHGLLSAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEALAAISFTFPVTLIISSIAIGIGAGVSTNLGRL
IGSGNAPRAKVFLHDALLLTFILIASLSALGSIFIKPLFSLLGANDTSLPLIHDYMMYWYVGAPLLVLLMVGNQGLRSTG
DTRSPAMIMALAAIINLILDPLLIFGIGPFPRLEIQGAAIATLFSWLIALSLSGYLLIIKRNMLEWAAFDIDRMRANWSK
LAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMPFIAQNLGAGQTQRAKQALLL
SLKFIFVFQTLLYIPLAFFAQPLAHLFSTDPQVLEWLSFYILVLPCAYGPLGIVIIFATALNAYHRPMSSLVINLCRLVL
LMLPLAALGSYIDGVKGLLLALPITNLLMGIACYYLAQRICEPAKVTTADAI

Sequences:

>Translated_452_residues
MKDRHGLLSAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEALAAISFTFPVTLIISSIAIGIGAGVSTNLGRL
IGSGNAPRAKVFLHDALLLTFILIASLSALGSIFIKPLFSLLGANDTSLPLIHDYMMYWYVGAPLLVLLMVGNQGLRSTG
DTRSPAMIMALAAIINLILDPLLIFGIGPFPRLEIQGAAIATLFSWLIALSLSGYLLIIKRNMLEWAAFDIDRMRANWSK
LAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMPFIAQNLGAGQTQRAKQALLL
SLKFIFVFQTLLYIPLAFFAQPLAHLFSTDPQVLEWLSFYILVLPCAYGPLGIVIIFATALNAYHRPMSSLVINLCRLVL
LMLPLAALGSYIDGVKGLLLALPITNLLMGIACYYLAQRICEPAKVTTADAI
>Mature_452_residues
MKDRHGLLSAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEALAAISFTFPVTLIISSIAIGIGAGVSTNLGRL
IGSGNAPRAKVFLHDALLLTFILIASLSALGSIFIKPLFSLLGANDTSLPLIHDYMMYWYVGAPLLVLLMVGNQGLRSTG
DTRSPAMIMALAAIINLILDPLLIFGIGPFPRLEIQGAAIATLFSWLIALSLSGYLLIIKRNMLEWAAFDIDRMRANWSK
LAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMPFIAQNLGAGQTQRAKQALLL
SLKFIFVFQTLLYIPLAFFAQPLAHLFSTDPQVLEWLSFYILVLPCAYGPLGIVIIFATALNAYHRPMSSLVINLCRLVL
LMLPLAALGSYIDGVKGLLLALPITNLLMGIACYYLAQRICEPAKVTTADAI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=332, Percent_Identity=21.9879518072289, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48612; Mature: 48612

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRHGLLSAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEALAAISFTFPVTL
CCCCCCCHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISSIAIGIGAGVSTNLGRLIGSGNAPRAKVFLHDALLLTFILIASLSALGSIFIKPLFS
HHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGANDTSLPLIHDYMMYWYVGAPLLVLLMVGNQGLRSTGDTRSPAMIMALAAIINLILD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLLIFGIGPFPRLEIQGAAIATLFSWLIALSLSGYLLIIKRNMLEWAAFDIDRMRANWSK
HHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FIAQNLGAGQTQRAKQALLLSLKFIFVFQTLLYIPLAFFAQPLAHLFSTDPQVLEWLSFY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ILVLPCAYGPLGIVIIFATALNAYHRPMSSLVINLCRLVLLMLPLAALGSYIDGVKGLLL
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPITNLLMGIACYYLAQRICEPAKVTTADAI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKDRHGLLSAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEALAAISFTFPVTL
CCCCCCCHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISSIAIGIGAGVSTNLGRLIGSGNAPRAKVFLHDALLLTFILIASLSALGSIFIKPLFS
HHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGANDTSLPLIHDYMMYWYVGAPLLVLLMVGNQGLRSTGDTRSPAMIMALAAIINLILD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLLIFGIGPFPRLEIQGAAIATLFSWLIALSLSGYLLIIKRNMLEWAAFDIDRMRANWSK
HHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FIAQNLGAGQTQRAKQALLLSLKFIFVFQTLLYIPLAFFAQPLAHLFSTDPQVLEWLSFY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ILVLPCAYGPLGIVIIFATALNAYHRPMSSLVINLCRLVLLMLPLAALGSYIDGVKGLLL
HHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPITNLLMGIACYYLAQRICEPAKVTTADAI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]