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The map label for this gene is bioD [H]

Identifier: 117920959

GI number: 117920959

Start: 3007834

End: 3008529

Strand: Reverse

Name: bioD [H]

Synonym: Shewana3_2516

Alternate gene names: 117920959

Gene position: 3008529-3007834 (Counterclockwise)

Preceding gene: 117920960

Following gene: 117920955

Centisome position: 60.51

GC content: 47.41

Gene sequence:

>696_bases
ATGTTTTTTGTAACAGGTACAGATACCGACAGTGGTAAAACCTTAGTGTCGACGGCACTGTTAACCGCATTCAATCGTGA
AGCTGCTCGCACAGGCGCTGCGCACTTAAGCCTTGGGGTAAAACCTGTGGCCTCGGGATGTGAAACCACAGCGCAGGGCT
TACGCAACAGTGATGCGTTAAAACTGATGTCGGCCTCATCTTTAAAGCTCAGCTATGAGCAGGTCAATCCGATAAGCTTT
GAACCCGCCATCGCGCCGCATATTGCCGCAAAACAGCTTGAGGTTAATTTATCTCCAGAGGCGATTTTGGCAGAACTCGA
CAGACAAGCCTTTGAGCAGGCTGATTTTTGCTTGATAGAAGGTGCGGGTGGCTGGCGTTTGCCCTTAGGGGACGGGCGTT
ATTTATCGGAATTAGTGCAGCAACTTAATTTGCCAGTGATCTTGGTTGTGGGAATGAAACTTGGCTGCTTAAATCATGCA
TTATTAACCCAAGAGGCGATAATCGCCGATGGCTTAACCGTGGCGGGTTGGGTGGCAAATTGCGTCGATCCCAATATGAG
CGTGTTTGATGAAAACTTAGCATCGCTTAAAGAGATGATGACATCGCCTTTCTTAGGTTGTGTTCCACATCTTAAGCAGG
CTGATGCAGAACATGCCGCCCATTTTATCGATATTCAAGCTTTGTTGATGAAATAA

Upstream 100 bases:

>100_bases
CAGATCGCTCAATTTTGTGTGCGCCGCCAAGACGATAGGGTGTAAGGCTCGTCGTTTAGTTTTGAGCGCGTGATTGACCA
TGGACTAATAAGGAAAACGC

Downstream 100 bases:

>100_bases
CCCATTCAAAAATACGTGTGATATAAAAAAAAGAGGCCATACAACCTCTTTTTTGTTATTGAGTGTTTAATTTGTTGTGA
CTAAAACTTAACTCGGTAGC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MFFVTGTDTDSGKTLVSTALLTAFNREAARTGAAHLSLGVKPVASGCETTAQGLRNSDALKLMSASSLKLSYEQVNPISF
EPAIAPHIAAKQLEVNLSPEAILAELDRQAFEQADFCLIEGAGGWRLPLGDGRYLSELVQQLNLPVILVVGMKLGCLNHA
LLTQEAIIADGLTVAGWVANCVDPNMSVFDENLASLKEMMTSPFLGCVPHLKQADAEHAAHFIDIQALLMK

Sequences:

>Translated_231_residues
MFFVTGTDTDSGKTLVSTALLTAFNREAARTGAAHLSLGVKPVASGCETTAQGLRNSDALKLMSASSLKLSYEQVNPISF
EPAIAPHIAAKQLEVNLSPEAILAELDRQAFEQADFCLIEGAGGWRLPLGDGRYLSELVQQLNLPVILVVGMKLGCLNHA
LLTQEAIIADGLTVAGWVANCVDPNMSVFDENLASLKEMMTSPFLGCVPHLKQADAEHAAHFIDIQALLMK
>Mature_231_residues
MFFVTGTDTDSGKTLVSTALLTAFNREAARTGAAHLSLGVKPVASGCETTAQGLRNSDALKLMSASSLKLSYEQVNPISF
EPAIAPHIAAKQLEVNLSPEAILAELDRQAFEQADFCLIEGAGGWRLPLGDGRYLSELVQQLNLPVILVVGMKLGCLNHA
LLTQEAIIADGLTVAGWVANCVDPNMSVFDENLASLKEMMTSPFLGCVPHLKQADAEHAAHFIDIQALLMK

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=219, Percent_Identity=48.4018264840183, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI87081944, Length=227, Percent_Identity=40.0881057268723, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24660; Mature: 24660

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFVTGTDTDSGKTLVSTALLTAFNREAARTGAAHLSLGVKPVASGCETTAQGLRNSDAL
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHCCHHHHHHHCCCCCHH
KLMSASSLKLSYEQVNPISFEPAIAPHIAAKQLEVNLSPEAILAELDRQAFEQADFCLIE
HHHCCCCCEEEHHHCCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHHHHHHHCCCEEEEE
GAGGWRLPLGDGRYLSELVQQLNLPVILVVGMKLGCLNHALLTQEAIIADGLTVAGWVAN
CCCCEECCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CVDPNMSVFDENLASLKEMMTSPFLGCVPHLKQADAEHAAHFIDIQALLMK
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFVTGTDTDSGKTLVSTALLTAFNREAARTGAAHLSLGVKPVASGCETTAQGLRNSDAL
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHCCHHHHHHHCCCCCHH
KLMSASSLKLSYEQVNPISFEPAIAPHIAAKQLEVNLSPEAILAELDRQAFEQADFCLIE
HHHCCCCCEEEHHHCCCCCCCCCCCHHHHHHHEEECCCHHHHHHHHHHHHHHCCCEEEEE
GAGGWRLPLGDGRYLSELVQQLNLPVILVVGMKLGCLNHALLTQEAIIADGLTVAGWVAN
CCCCEECCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CVDPNMSVFDENLASLKEMMTSPFLGCVPHLKQADAEHAAHFIDIQALLMK
HCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA