Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 117920955

GI number: 117920955

Start: 3002225

End: 3003088

Strand: Reverse

Name: htpX [H]

Synonym: Shewana3_2512

Alternate gene names: 117920955

Gene position: 3003088-3002225 (Counterclockwise)

Preceding gene: 117920959

Following gene: 117920954

Centisome position: 60.4

GC content: 50.12

Gene sequence:

>864_bases
ATGAAGCGTATTTTTTTATTAATTGCGACTAACCTAGCCGTGTTGCTGGTAGCCTCAATTGTGATGTCTATTCTGGGCGT
GAATACGTCGACTATGGGTGGACTGCTTGTGTTCGCTGCGATTTTTGGATTCGGCGGAGCCTTCATCAGCTTAGCCATTT
CAAAATGGATGGCGAAAAAGACCATGGGCTGTGAAGTGATCACCACTCCCCGTGATAGCACAGAGCGTTGGTTATTAGAC
ACTGTTGCCCGTCAAGCGCAGCAAGCTGGGATTAAAATGCCAGAAGTGGCAATTTACCAATCGCCAGAGATGAATGCCTT
CGCCACAGGCCCAAGCAAAGACAACTCATTAGTTGCCGTGAGTACCGGTCTGTTGTATGGCATGAGCCAAGACGAAGTTG
AAGGCGTACTCGCCCACGAAGTGAGCCACGTTGCCAACGGCGACATGGTGACCTTGACCTTAATTCAAGGCGTGGTGAAC
ACCTTTGTTATCTTCGCGGCACGTGTTGTTGCGGGCATTATCAACAACTTCGTCTCGAGCAACGATGAAGAGGGTGAAGG
TTTAGGCATGTTCGCCTATATGGCGGTCGTGTTTGTCCTCGACATGTTGTTTGGTATCTTGGCCTCGATCATCGTGGCTT
ACTTCTCACGTATCCGTGAATACCGTGCTGACGAAGGTGCGGCGCGTTTAGCGGGCAAACATAAGATGATTGCAGCGCTT
GAGCGTTTACGCCAAGGCCCTGAAAGCTCGGCAATGCCAGCACAAATGTCGGCTTTTGGTATTAACGGTAAGCGTTCAAT
GGCTGAGCTGATGATGAGCCACCCGCCATTAGAGAAGCGTATCGCCGCCTTACAAACTCGTTAA

Upstream 100 bases:

>100_bases
TAGAAAAACTCTTATCTTTACCCCTTGAATTTCGATTAATTGGACATATTATGTCTTTGAGCAAAGTTAAATGGCATATG
TTTGCCGTAAAGGAGCTGAA

Downstream 100 bases:

>100_bases
TCGAGTTCAAAAGTTCACAAAAAGGAGACCTAGGGTCTCCTTTTTTATTGGGGCTTTTCTTTTGCTGATGACTAGGCTAG
GGAGGTTTTTAGTTGTGACT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLLD
TVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAVSTGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVN
TFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAAL
ERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR

Sequences:

>Translated_287_residues
MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLLD
TVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAVSTGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVN
TFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAAL
ERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR
>Mature_287_residues
MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLLD
TVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAVSTGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVN
TFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAAL
ERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=289, Percent_Identity=56.7474048442907, Blast_Score=327, Evalue=5e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30889; Mature: 30889

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKK
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMGCEVITTPRDSTERWLLDTVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAV
HCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCEEEE
STGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSS
EHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR
HHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKK
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMGCEVITTPRDSTERWLLDTVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAV
HCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCEEEE
STGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSS
EHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR
HHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA