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The map label for this gene is bioC [H]

Identifier: 117920960

GI number: 117920960

Start: 3008585

End: 3009412

Strand: Reverse

Name: bioC [H]

Synonym: Shewana3_2517

Alternate gene names: 117920960

Gene position: 3009412-3008585 (Counterclockwise)

Preceding gene: 117920961

Following gene: 117920959

Centisome position: 60.52

GC content: 51.21

Gene sequence:

>828_bases
ATGTCTATGCCGCTTGGCGTGAGTGTACATTCCCATCCATCTGCCAGTCAGGTCGAGCATATTGCCGATAGGTTTTCTGC
TGCGGCCAAGCGCTACCAAGAGCATAACTGTTTACAGCGTTTAAGCGGCGCGAGTTTGTTGCAGGGATTTGCTGCCAAGG
GCGCAATTCTTGATATTGGCGCGGGGCCGGGGACCGATTTTGCCGACCGTGCAGTGGGTGACAATATCAAGGTTTATGCC
CTCGATATCGCCCTCGGAATGCTGCAACAACTTCAAGTGACTTTCCCTCGGTACCAATGTGTGTGCGGTAATGCCGAGCA
ACTCCCCTTTGCCGATGGGAGTATCGATAGTATTTACTCCAATTTAGCCCTGCAGTGGTGCCATGATTTTTCGGCTGCGA
CCAGTGAAATGGCCAGAGTCTTAAAACCCGGTGGAGAAGCGCACCTGAGTATTGTGGCCGAAGGCAGCCTGGCGCAGTTA
TCCCATCTTGGTTTGAGGGTGAACGGTTTTCAATCCCTTGAAAGCTTACAAGTCGCCTTTGATACCTCTGATTGGCAACT
GTTTGATGTCCAACTTGTGCCAATGACCGTCTATTTTCAAGATCTTAAAACCTTGCTCTATTCCATAAAGGGTGTGGGCG
CATCGGTGCAATCGTACATACAGACCGAAAACTCTTCAGATGTCGATGCTCACTTAGGCAAATTGCGGGGCCGCCGCGAT
TGGCTGGCACTACAACAACGCGCAGAACTATTCCGTGAGGCTCAGGGCCTGCCTTTAACCTATCAGATCGCTCAATTTTG
TGTGCGCCGCCAAGACGATAGGGTGTAA

Upstream 100 bases:

>100_bases
AGCTTGAAGATAAGAGCTTGAATGTAAGAGTCTGAAAGTAAGAGCTTGAAGATAAAAGCTTCTAAGTAAAAGTTTGATGT
TAAAGTGAGAATAATTTGTG

Downstream 100 bases:

>100_bases
GGCTCGTCGTTTAGTTTTGAGCGCGTGATTGACCATGGACTAATAAGGAAAACGCATGTTTTTTGTAACAGGTACAGATA
CCGACAGTGGTAAAACCTTA

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSMPLGVSVHSHPSASQVEHIADRFSAAAKRYQEHNCLQRLSGASLLQGFAAKGAILDIGAGPGTDFADRAVGDNIKVYA
LDIALGMLQQLQVTFPRYQCVCGNAEQLPFADGSIDSIYSNLALQWCHDFSAATSEMARVLKPGGEAHLSIVAEGSLAQL
SHLGLRVNGFQSLESLQVAFDTSDWQLFDVQLVPMTVYFQDLKTLLYSIKGVGASVQSYIQTENSSDVDAHLGKLRGRRD
WLALQQRAELFREAQGLPLTYQIAQFCVRRQDDRV

Sequences:

>Translated_275_residues
MSMPLGVSVHSHPSASQVEHIADRFSAAAKRYQEHNCLQRLSGASLLQGFAAKGAILDIGAGPGTDFADRAVGDNIKVYA
LDIALGMLQQLQVTFPRYQCVCGNAEQLPFADGSIDSIYSNLALQWCHDFSAATSEMARVLKPGGEAHLSIVAEGSLAQL
SHLGLRVNGFQSLESLQVAFDTSDWQLFDVQLVPMTVYFQDLKTLLYSIKGVGASVQSYIQTENSSDVDAHLGKLRGRRD
WLALQQRAELFREAQGLPLTYQIAQFCVRRQDDRV
>Mature_274_residues
SMPLGVSVHSHPSASQVEHIADRFSAAAKRYQEHNCLQRLSGASLLQGFAAKGAILDIGAGPGTDFADRAVGDNIKVYAL
DIALGMLQQLQVTFPRYQCVCGNAEQLPFADGSIDSIYSNLALQWCHDFSAATSEMARVLKPGGEAHLSIVAEGSLAQLS
HLGLRVNGFQSLESLQVAFDTSDWQLFDVQLVPMTVYFQDLKTLLYSIKGVGASVQSYIQTENSSDVDAHLGKLRGRRDW
LALQQRAELFREAQGLPLTYQIAQFCVRRQDDRV

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=192, Percent_Identity=30.2083333333333, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 30148; Mature: 30017

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPLGVSVHSHPSASQVEHIADRFSAAAKRYQEHNCLQRLSGASLLQGFAAKGAILDIG
CCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECC
AGPGTDFADRAVGDNIKVYALDIALGMLQQLQVTFPRYQCVCGNAEQLPFADGSIDSIYS
CCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHH
NLALQWCHDFSAATSEMARVLKPGGEAHLSIVAEGSLAQLSHLGLRVNGFQSLESLQVAF
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCEEECCHHHHHHHHEEE
DTSDWQLFDVQLVPMTVYFQDLKTLLYSIKGVGASVQSYIQTENSSDVDAHLGKLRGRRD
ECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCHH
WLALQQRAELFREAQGLPLTYQIAQFCVRRQDDRV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SMPLGVSVHSHPSASQVEHIADRFSAAAKRYQEHNCLQRLSGASLLQGFAAKGAILDIG
CCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECC
AGPGTDFADRAVGDNIKVYALDIALGMLQQLQVTFPRYQCVCGNAEQLPFADGSIDSIYS
CCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHH
NLALQWCHDFSAATSEMARVLKPGGEAHLSIVAEGSLAQLSHLGLRVNGFQSLESLQVAF
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCEEECCHHHHHHHHEEE
DTSDWQLFDVQLVPMTVYFQDLKTLLYSIKGVGASVQSYIQTENSSDVDAHLGKLRGRRD
ECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCHH
WLALQQRAELFREAQGLPLTYQIAQFCVRRQDDRV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9063571 [H]