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The map label for this gene is arsB [H]

Identifier: 117920787

GI number: 117920787

Start: 2820383

End: 2821666

Strand: Direct

Name: arsB [H]

Synonym: Shewana3_2344

Alternate gene names: 117920787

Gene position: 2820383-2821666 (Clockwise)

Preceding gene: 117920786

Following gene: 117920788

Centisome position: 56.72

GC content: 50.7

Gene sequence:

>1284_bases
ATGTGGTTGGCAGGGGCGATTTTTGTTCTCACCATAGTGTTAGTGATTTGGCAACCTAAGGGTTTAGGCATAGGTTGGAG
TGCCACCTTGGGCGCCGTATTGGCCTTGCTATTAGGCGTAGTGCAGTTAGGGGATATTCCCGTGGTGTGGAATATCGTCT
GGAATGCGACCGCCACCTTTATCGCCGTGATCATCATCAGTTTATTATTGGATGAGTCAGGATTTTTCGAATGGGCCGCG
CTGCATGTGGCCCGCTGGGGTAAAGGTCGTGGCCGTTTACTCTTTACTTACATAGTGTTACTCGGTGCTACCGTTGCAGC
CTTATTCGCCAATGATGGCGCGGCGCTGATCCTCACCCCAATCGTGATTGCGATGTTACTGGCGCTGGGCTTTAGCGCCG
GAGCCACCTTAGCCTTTGTGATGGCCGCAGGTTTTATTGCCGATACCGCAAGTTTGCCGTTAATCGTCTCTAACCTAGTG
AATATCGTTTCCGCGGACTTTTTCAAGATAGGCTTTAACGAATATGCCGCTGTAATGGTGCCCGTCGATATTGCCGCGAT
TAGCGCCACATTAGTGATGCTGCATGTGTTTTTCCGCAAAGATATTCCAGCCACCTACGACCTAGAAAAACTGCGCGAGC
CTAAGGCCGCAATTCGCGACCTCAACACCTTTAAAACCGGTTGGGGAGTTTTAGTCTTACTCTTAGTCGGCTTTTTTGGC
CTAGAACCCCTCGGCGTGCCCGTGAGTTTAGTTGCTGCCGTGGGCGCGCTTATTCTGTTTGTGGTCGCCAAGAAAGGCCA
TGGGATAGATACCACTAAGGTACTGCGCGGCGCACCATGGCAAATAGTGATCTTTTCACTGGGTATGTATCTGGTGGTTT
ATGGTCTGCGTAACGCAGGCTTAACGGATTATCTATCTCACGTGTTGGACAGCTTGGCAGCACAAGGACTTTGGGTTGCC
ACTATGGGCACAGGTTTTTTAGTCGCCTTTTTATCTTCCATCATGAACAACATGCCAACCGTGTTAGTCGGCGCCCTGTC
GATAGACGGTAGCAATGCAACCGGCGTGATTAAAGTAGCCATGATCTACGCTAACGTGATAGGCAGCGATTTAGGCCCCA
AAATCACCCCTATCGGCAGTTTAGCAACCCTGCTATGGCTGCATGTGCTGGCGCAGAAAAATATCAATATAACTTGGGGT
TACTATTTCCGCGTCGGCATAGTGATGACAGTACCTGTGCTGTTTGTCACCCTAGCGGCACTGGCGCTGCGCCTCTCCTT
CTGA

Upstream 100 bases:

>100_bases
ATTGAACGATTAAGCCAATTGGCAAAATAGCGTTAATGTGCCTCAATGGGCATTATTTTATGGTTATGGGCAGGCAATAG
CTGCCCTTTTAGGAGGTTTT

Downstream 100 bases:

>100_bases
TCTATGACCATAGGCACTTAATCATCCATTTAGTGCCTATGGATAAATGTATAAGCGATTATTTATCAGAGAGAAGCTAT
CAGAGAAAAGTTATCAGAGA

Product: arsenical pump membrane protein

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MWLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALLLGVVQLGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAA
LHVARWGKGRGRLLFTYIVLLGATVAALFANDGAALILTPIVIAMLLALGFSAGATLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFKIGFNEYAAVMVPVDIAAISATLVMLHVFFRKDIPATYDLEKLREPKAAIRDLNTFKTGWGVLVLLLVGFFG
LEPLGVPVSLVAAVGALILFVVAKKGHGIDTTKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLSHVLDSLAAQGLWVA
TMGTGFLVAFLSSIMNNMPTVLVGALSIDGSNATGVIKVAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKNINITWG
YYFRVGIVMTVPVLFVTLAALALRLSF

Sequences:

>Translated_427_residues
MWLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALLLGVVQLGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAA
LHVARWGKGRGRLLFTYIVLLGATVAALFANDGAALILTPIVIAMLLALGFSAGATLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFKIGFNEYAAVMVPVDIAAISATLVMLHVFFRKDIPATYDLEKLREPKAAIRDLNTFKTGWGVLVLLLVGFFG
LEPLGVPVSLVAAVGALILFVVAKKGHGIDTTKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLSHVLDSLAAQGLWVA
TMGTGFLVAFLSSIMNNMPTVLVGALSIDGSNATGVIKVAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKNINITWG
YYFRVGIVMTVPVLFVTLAALALRLSF
>Mature_427_residues
MWLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALLLGVVQLGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAA
LHVARWGKGRGRLLFTYIVLLGATVAALFANDGAALILTPIVIAMLLALGFSAGATLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFKIGFNEYAAVMVPVDIAAISATLVMLHVFFRKDIPATYDLEKLREPKAAIRDLNTFKTGWGVLVLLLVGFFG
LEPLGVPVSLVAAVGALILFVVAKKGHGIDTTKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLSHVLDSLAAQGLWVA
TMGTGFLVAFLSSIMNNMPTVLVGALSIDGSNATGVIKVAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKNINITWG
YYFRVGIVMTVPVLFVTLAALALRLSF

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082277, Length=427, Percent_Identity=85.480093676815, Blast_Score=687, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 45396; Mature: 45396

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALLLGVVQLGDIPVVWNIVWNATATF
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
IAVIIISLLLDESGFFEWAALHVARWGKGRGRLLFTYIVLLGATVAALFANDGAALILTP
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IVIAMLLALGFSAGATLAFVMAAGFIADTASLPLIVSNLVNIVSADFFKIGFNEYAAVMV
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
PVDIAAISATLVMLHVFFRKDIPATYDLEKLREPKAAIRDLNTFKTGWGVLVLLLVGFFG
EHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LEPLGVPVSLVAAVGALILFVVAKKGHGIDTTKVLRGAPWQIVIFSLGMYLVVYGLRNAG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
LTDYLSHVLDSLAAQGLWVATMGTGFLVAFLSSIMNNMPTVLVGALSIDGSNATGVIKVA
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHH
MIYANVIGSDLGPKITPIGSLATLLWLHVLAQKNINITWGYYFRVGIVMTVPVLFVTLAA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHH
LALRLSF
HHHHCCC
>Mature Secondary Structure
MWLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALLLGVVQLGDIPVVWNIVWNATATF
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
IAVIIISLLLDESGFFEWAALHVARWGKGRGRLLFTYIVLLGATVAALFANDGAALILTP
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IVIAMLLALGFSAGATLAFVMAAGFIADTASLPLIVSNLVNIVSADFFKIGFNEYAAVMV
HHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
PVDIAAISATLVMLHVFFRKDIPATYDLEKLREPKAAIRDLNTFKTGWGVLVLLLVGFFG
EHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LEPLGVPVSLVAAVGALILFVVAKKGHGIDTTKVLRGAPWQIVIFSLGMYLVVYGLRNAG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
LTDYLSHVLDSLAAQGLWVATMGTGFLVAFLSSIMNNMPTVLVGALSIDGSNATGVIKVA
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHH
MIYANVIGSDLGPKITPIGSLATLLWLHVLAQKNINITWGYYFRVGIVMTVPVLFVTLAA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHH
LALRLSF
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3021763; 2523997; 1688427; 1704144 [H]