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The map label for this gene is arsA [H]

Identifier: 117920786

GI number: 117920786

Start: 2818546

End: 2820312

Strand: Direct

Name: arsA [H]

Synonym: Shewana3_2343

Alternate gene names: 117920786

Gene position: 2818546-2820312 (Clockwise)

Preceding gene: 117920785

Following gene: 117920787

Centisome position: 56.69

GC content: 50.03

Gene sequence:

>1767_bases
ATGAAATTTATTAAAAATCCGCCCGCATTTCTCTTTTTTACCGGTAAAGGCGGTGTTGGTAAGACTTCGCTATCCTGCGC
CACAGCAATCAACTTAGCCGACAAAGGAAAACGGGTGTTGTTGGTCAGTACCGACCCAGCCTCCAATGTGGGCCAGGTTT
TTGGGCAAACTATAGGTAATCAACTTACCCCTATTGATAGCGTTGCTGGACTCACGGCTCTGGAAATTGATCCCCAAGCC
GCCGCAGCACAATACCGTGCCCGGATTGTCGATCCCGTCAAAGGGATCTTACCGCCTGATGTGGTTCGCAGTATTGAAGA
GCAACTCTCCGGTGCCTGCACTACTGAAATTGCCGCCTTCGATGAATTTACTGGCTTATTGACCGATGATTCATTACAGC
AAGATTTCGATCATATTATTTTTGATACCGCGCCAACGGGACATACTATCCGCTTGCTCCAACTCCCCGGCGCTTGGAGC
AGTTTTATCGAGGCGAACCCCGAGGGGGCATCCTGTCTTGGCCCATTAGCGGGCCTCGAAAAACAGGCGGAGCGTTACGC
GCAGGCCTTAATAGCACTGGCCGATCCCGATAAGACACGCTTGATCTTAGTTGCGCGCCCACAGCAATCCACTCTGATTG
AAGTGGAACGCACTCACCAAGAGTTACGTCAAGTGGGCCTTAAAAATCAATATCTAGTGATTAACGGCGTATTACCCCAA
AACGCGGCACTTGATGATCCCCTTGCCAATGCGCTCTACCGACGAGAACAAGCTGTGCTCGCCAATTTATCTCCCATTCT
CGCGGCATTGCCCCATGAAACCTTGCCGTTGCAATCCATGAATATGGTGGGTGTTGCACCATTACGCCAACTCTTGCTGC
CAGCGCAACCCAATGACTTACTTAACATTAATGAGCATGAGCAATCTCATCAAGGTAGCCATCCCCAAGTGCCAACACTG
GATAACCTCATCGGTGAAATCGCTAAACAAGACCATGGCCTTATCATGTTGATGGGCAAAGGCGGTGTTGGTAAAACCAC
CTTAGCGGCCGCAATTGCGGTGAGATTGGCGGAGCTCGGTTTAGATGTGCATCTGACGACTTCAGATCCCGCTGCGCATT
TAGAACACACTCTTCATGGTCAATTAGCGAATTTGCAAGTCAGCAGAATCGATCCTGTTGAAGTCACCACTCGCTACCGT
GAACAAGTGTTAGCCACCAAAGGCAAAGAATTAGATGCCCAAGGTAAGGCCTTGCTAGAAGAGGATTTACGCTCACCTTG
CACCGAAGAAATCGCTGTATTTCAAGCATTTTCGCGGATTATCCGCGAGGCGGGTAAACGCTTTGTCGTCATGGATACCG
CACCCACTGGGCATACCCTATTGCTACTCGATGCCACGGGCGCCTACCACCGTGAAGTCGCCAAACGTATGGGAGAAACG
ACTCACTATTCAACCCCTATGATGCAGTTACAGGACAAAGAGCGCACTAAGGTGTTATTAGTCACCCTACCCGAAACCAC
ACCCGTGCTCGAAGCCGCTAATTTACAAGAGGATTTGCGCCGTGCAGGGATCGAGCCTTGGGCATGGCTTATCAATAACA
GCCTCGCCGTTGCGAGAACAACCTCGCCACTATTAAAAGTGCGCGCTCGCCATGAAGTGGCACAAATCGACAAAGTACAA
CGGGGTTTAGCCTCTAGATTGGCATTAATCCCACTGCAGGAAGAAGAACCCATTGGTATTGAACGATTAAGCCAATTGGC
AAAATAG

Upstream 100 bases:

>100_bases
CGTTGGGCCAAAATCACTCTCGAAGCACCAGCTACAGAAGCGACGTCTTGTTGCAGCGGCAAGAGCGCTTGCTGCTAATC
AACGAACTAAGGATAACAGC

Downstream 100 bases:

>100_bases
CGTTAATGTGCCTCAATGGGCATTATTTTATGGTTATGGGCAGGCAATAGCTGCCCTTTTAGGAGGTTTTATGTGGTTGG
CAGGGGCGATTTTTGTTCTC

Product: arsenite-activated ATPase ArsA

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MKFIKNPPAFLFFTGKGGVGKTSLSCATAINLADKGKRVLLVSTDPASNVGQVFGQTIGNQLTPIDSVAGLTALEIDPQA
AAAQYRARIVDPVKGILPPDVVRSIEEQLSGACTTEIAAFDEFTGLLTDDSLQQDFDHIIFDTAPTGHTIRLLQLPGAWS
SFIEANPEGASCLGPLAGLEKQAERYAQALIALADPDKTRLILVARPQQSTLIEVERTHQELRQVGLKNQYLVINGVLPQ
NAALDDPLANALYRREQAVLANLSPILAALPHETLPLQSMNMVGVAPLRQLLLPAQPNDLLNINEHEQSHQGSHPQVPTL
DNLIGEIAKQDHGLIMLMGKGGVGKTTLAAAIAVRLAELGLDVHLTTSDPAAHLEHTLHGQLANLQVSRIDPVEVTTRYR
EQVLATKGKELDAQGKALLEEDLRSPCTEEIAVFQAFSRIIREAGKRFVVMDTAPTGHTLLLLDATGAYHREVAKRMGET
THYSTPMMQLQDKERTKVLLVTLPETTPVLEAANLQEDLRRAGIEPWAWLINNSLAVARTTSPLLKVRARHEVAQIDKVQ
RGLASRLALIPLQEEEPIGIERLSQLAK

Sequences:

>Translated_588_residues
MKFIKNPPAFLFFTGKGGVGKTSLSCATAINLADKGKRVLLVSTDPASNVGQVFGQTIGNQLTPIDSVAGLTALEIDPQA
AAAQYRARIVDPVKGILPPDVVRSIEEQLSGACTTEIAAFDEFTGLLTDDSLQQDFDHIIFDTAPTGHTIRLLQLPGAWS
SFIEANPEGASCLGPLAGLEKQAERYAQALIALADPDKTRLILVARPQQSTLIEVERTHQELRQVGLKNQYLVINGVLPQ
NAALDDPLANALYRREQAVLANLSPILAALPHETLPLQSMNMVGVAPLRQLLLPAQPNDLLNINEHEQSHQGSHPQVPTL
DNLIGEIAKQDHGLIMLMGKGGVGKTTLAAAIAVRLAELGLDVHLTTSDPAAHLEHTLHGQLANLQVSRIDPVEVTTRYR
EQVLATKGKELDAQGKALLEEDLRSPCTEEIAVFQAFSRIIREAGKRFVVMDTAPTGHTLLLLDATGAYHREVAKRMGET
THYSTPMMQLQDKERTKVLLVTLPETTPVLEAANLQEDLRRAGIEPWAWLINNSLAVARTTSPLLKVRARHEVAQIDKVQ
RGLASRLALIPLQEEEPIGIERLSQLAK
>Mature_588_residues
MKFIKNPPAFLFFTGKGGVGKTSLSCATAINLADKGKRVLLVSTDPASNVGQVFGQTIGNQLTPIDSVAGLTALEIDPQA
AAAQYRARIVDPVKGILPPDVVRSIEEQLSGACTTEIAAFDEFTGLLTDDSLQQDFDHIIFDTAPTGHTIRLLQLPGAWS
SFIEANPEGASCLGPLAGLEKQAERYAQALIALADPDKTRLILVARPQQSTLIEVERTHQELRQVGLKNQYLVINGVLPQ
NAALDDPLANALYRREQAVLANLSPILAALPHETLPLQSMNMVGVAPLRQLLLPAQPNDLLNINEHEQSHQGSHPQVPTL
DNLIGEIAKQDHGLIMLMGKGGVGKTTLAAAIAVRLAELGLDVHLTTSDPAAHLEHTLHGQLANLQVSRIDPVEVTTRYR
EQVLATKGKELDAQGKALLEEDLRSPCTEEIAVFQAFSRIIREAGKRFVVMDTAPTGHTLLLLDATGAYHREVAKRMGET
THYSTPMMQLQDKERTKVLLVTLPETTPVLEAANLQEDLRRAGIEPWAWLINNSLAVARTTSPLLKVRARHEVAQIDKVQ
RGLASRLALIPLQEEEPIGIERLSQLAK

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=262, Percent_Identity=28.6259541984733, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17557003, Length=248, Percent_Identity=29.4354838709677, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320103, Length=244, Percent_Identity=30.7377049180328, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24586297, Length=299, Percent_Identity=23.7458193979933, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003593
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 63910; Mature: 63910

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIKNPPAFLFFTGKGGVGKTSLSCATAINLADKGKRVLLVSTDPASNVGQVFGQTIGN
CCCCCCCCEEEEEECCCCCCCCCCHHHHHEECCCCCCEEEEEECCCCCHHHHHHHHHHCC
QLTPIDSVAGLTALEIDPQAAAAQYRARIVDPVKGILPPDVVRSIEEQLSGACTTEIAAF
CCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
DEFTGLLTDDSLQQDFDHIIFDTAPTGHTIRLLQLPGAWSSFIEANPEGASCLGPLAGLE
HHHHCCCCCCHHHHHHHHEEEECCCCCCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHH
KQAERYAQALIALADPDKTRLILVARPQQSTLIEVERTHQELRQVGLKNQYLVINGVLPQ
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
NAALDDPLANALYRREQAVLANLSPILAALPHETLPLQSMNMVGVAPLRQLLLPAQPNDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
LNINEHEQSHQGSHPQVPTLDNLIGEIAKQDHGLIMLMGKGGVGKTTLAAAIAVRLAELG
CCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
LDVHLTTSDPAAHLEHTLHGQLANLQVSRIDPVEVTTRYREQVLATKGKELDAQGKALLE
CEEEEECCCCHHHHHHHHCCHHHCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
EDLRSPCTEEIAVFQAFSRIIREAGKRFVVMDTAPTGHTLLLLDATGAYHREVAKRMGET
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHCCCC
THYSTPMMQLQDKERTKVLLVTLPETTPVLEAANLQEDLRRAGIEPWAWLINNSLAVART
CCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEC
TSPLLKVRARHEVAQIDKVQRGLASRLALIPLQEEEPIGIERLSQLAK
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MKFIKNPPAFLFFTGKGGVGKTSLSCATAINLADKGKRVLLVSTDPASNVGQVFGQTIGN
CCCCCCCCEEEEEECCCCCCCCCCHHHHHEECCCCCCEEEEEECCCCCHHHHHHHHHHCC
QLTPIDSVAGLTALEIDPQAAAAQYRARIVDPVKGILPPDVVRSIEEQLSGACTTEIAAF
CCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
DEFTGLLTDDSLQQDFDHIIFDTAPTGHTIRLLQLPGAWSSFIEANPEGASCLGPLAGLE
HHHHCCCCCCHHHHHHHHEEEECCCCCCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHH
KQAERYAQALIALADPDKTRLILVARPQQSTLIEVERTHQELRQVGLKNQYLVINGVLPQ
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
NAALDDPLANALYRREQAVLANLSPILAALPHETLPLQSMNMVGVAPLRQLLLPAQPNDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
LNINEHEQSHQGSHPQVPTLDNLIGEIAKQDHGLIMLMGKGGVGKTTLAAAIAVRLAELG
CCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
LDVHLTTSDPAAHLEHTLHGQLANLQVSRIDPVEVTTRYREQVLATKGKELDAQGKALLE
CEEEEECCCCHHHHHHHHCCHHHCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
EDLRSPCTEEIAVFQAFSRIIREAGKRFVVMDTAPTGHTLLLLDATGAYHREVAKRMGET
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHCCCC
THYSTPMMQLQDKERTKVLLVTLPETTPVLEAANLQEDLRRAGIEPWAWLINNSLAVART
CCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEC
TSPLLKVRARHEVAQIDKVQRGLASRLALIPLQEEEPIGIERLSQLAK
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3021763; 1704144 [H]