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The map label for this gene is arsC [H]

Identifier: 117920779

GI number: 117920779

Start: 2810738

End: 2811154

Strand: Reverse

Name: arsC [H]

Synonym: Shewana3_2336

Alternate gene names: 117920779

Gene position: 2811154-2810738 (Counterclockwise)

Preceding gene: 117920780

Following gene: 117920778

Centisome position: 56.54

GC content: 40.05

Gene sequence:

>417_bases
ATGAAAAAACGCATACTTTTTCTCTGTGTTGGAAATTCGGCACGTTCGCAACTCGCTGAAGCCTTGTTAAAACATCAAGC
ACAAGATCTGTTTGAGGTATTTAGCGCGGGGACTGAGCCAGAGCCGATAGACGAACGAACCTTATATGTTTTGCAGAAAA
ATAATCTAGACACGAGCGAATTACGTTCTAAATCTGTCAATGAATTCAGTGGGCAATCCTTTGATTTTGTGATCAGCCTC
TGTGAAAAATCCACGCAAGAATGCCAGAGTTTTCCCTTAGCAGATAAGATTATTGCTTGGGATTATCCCGATCCCAGAAT
AGAATCGGGCACTCGTGGGTTTGAACAAACTTTTAGAGAACTCAACGAAAGAATAAAAATGTTTGTACTCGTTCAGTCTA
AGGATCTTAATGATTAA

Upstream 100 bases:

>100_bases
AATGAGACGTTTGTTAGGGGATGATAAATCCTTTGATATGGATATTTACATATACGATAATTCGTATATAGTGTCGGTAT
CTTTATAAGGACTCATTCCT

Downstream 100 bases:

>100_bases
TCCTACGCAATTTTTTAAATGTTTAGCCGACGAAACGCGCCTGCGTTGTTTGATGCTTATTCAGCACGAGGGTGAGCTTT
GCGTCTGTGAGTTGACCGAA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKKRILFLCVGNSARSQLAEALLKHQAQDLFEVFSAGTEPEPIDERTLYVLQKNNLDTSELRSKSVNEFSGQSFDFVISL
CEKSTQECQSFPLADKIIAWDYPDPRIESGTRGFEQTFRELNERIKMFVLVQSKDLND

Sequences:

>Translated_138_residues
MKKRILFLCVGNSARSQLAEALLKHQAQDLFEVFSAGTEPEPIDERTLYVLQKNNLDTSELRSKSVNEFSGQSFDFVISL
CEKSTQECQSFPLADKIIAWDYPDPRIESGTRGFEQTFRELNERIKMFVLVQSKDLND
>Mature_138_residues
MKKRILFLCVGNSARSQLAEALLKHQAQDLFEVFSAGTEPEPIDERTLYVLQKNNLDTSELRSKSVNEFSGQSFDFVISL
CEKSTQECQSFPLADKIIAWDYPDPRIESGTRGFEQTFRELNERIKMFVLVQSKDLND

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15857; Mature: 15857

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRILFLCVGNSARSQLAEALLKHQAQDLFEVFSAGTEPEPIDERTLYVLQKNNLDTSE
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHH
LRSKSVNEFSGQSFDFVISLCEKSTQECQSFPLADKIIAWDYPDPRIESGTRGFEQTFRE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCHHHHHHHH
LNERIKMFVLVQSKDLND
HHHHHHEEEEEECCCCCC
>Mature Secondary Structure
MKKRILFLCVGNSARSQLAEALLKHQAQDLFEVFSAGTEPEPIDERTLYVLQKNNLDTSE
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHH
LRSKSVNEFSGQSFDFVISLCEKSTQECQSFPLADKIIAWDYPDPRIESGTRGFEQTFRE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCCCHHHHHHHH
LNERIKMFVLVQSKDLND
HHHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]