Click here to switch to the map view.

The map label for this gene is nudL [H]

Identifier: 117920747

GI number: 117920747

Start: 2769425

End: 2770012

Strand: Direct

Name: nudL [H]

Synonym: Shewana3_2304

Alternate gene names: 117920747

Gene position: 2769425-2770012 (Clockwise)

Preceding gene: 117920746

Following gene: 117920749

Centisome position: 55.7

GC content: 50.34

Gene sequence:

>588_bases
ATGGATCAAGCGGAATTTAGACTCAGATTTAATCTGCATCCTTTAGCCACGCAAGATCCGGCGGCTATCCCTCACCTTGG
GTTGCGTAAAGCCGCAGTACTCATTCCCTTGCAGGAAATCCAGGGCGAGCTCAGTCTGATTTTAACCCAAAGACCGATGC
ACCTTAGGGCGCACCCTGGGCAAATTAGCTTTCCAGGCGGCAAGATTGAGCCCAGTGATAGTAGCGCCATTACGGCCGCG
CTGCGGGAAGCGGAAGAAGAAATTGGTCTTTGCCGAGAAAATGTAGAAGTGATAGGCACTTTCCCCGCCCATAACACCTT
TACCGGTTTTGAAATCACTCCAGTGGTGGGCATGATTAAGCAGGATTTTGCCTTAAGGCTCGATCCCGGTGAAGTCGCCG
ATTGCTTTACCGTACCCTTAAGTTTTTTTATCGAACCGCAAAATCGCCACCGCAAACAGTTTTTACGCCAAGGGCGTTAT
TACAGCGTGCATTTTATTCCGTATCAGCAACGTTTTATCTGGGGCGCGACGGCGGCGATTATCGATCACCTCTGTCGGCA
TTTGAGTCTTCCCGAGGAGATGCTGTAA

Upstream 100 bases:

>100_bases
AATGTCGATGCCGAGTACCAAGAAAGCTTCGATAAGATAAGCCGCATCTTACCCTTGCTCGATAGCCCTCAATAAGCGTC
AGGAAACGAATAGGAAGCCA

Downstream 100 bases:

>100_bases
ACCCGCATTGCTCATTTGGATAATTCAAATCACAAAATGCACATATAAGCCCGCCACTAACGAGGTTAGCAGCAGCAAGG
GAATATTAAACCAATAACCC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MDQAEFRLRFNLHPLATQDPAAIPHLGLRKAAVLIPLQEIQGELSLILTQRPMHLRAHPGQISFPGGKIEPSDSSAITAA
LREAEEEIGLCRENVEVIGTFPAHNTFTGFEITPVVGMIKQDFALRLDPGEVADCFTVPLSFFIEPQNRHRKQFLRQGRY
YSVHFIPYQQRFIWGATAAIIDHLCRHLSLPEEML

Sequences:

>Translated_195_residues
MDQAEFRLRFNLHPLATQDPAAIPHLGLRKAAVLIPLQEIQGELSLILTQRPMHLRAHPGQISFPGGKIEPSDSSAITAA
LREAEEEIGLCRENVEVIGTFPAHNTFTGFEITPVVGMIKQDFALRLDPGEVADCFTVPLSFFIEPQNRHRKQFLRQGRY
YSVHFIPYQQRFIWGATAAIIDHLCRHLSLPEEML
>Mature_195_residues
MDQAEFRLRFNLHPLATQDPAAIPHLGLRKAAVLIPLQEIQGELSLILTQRPMHLRAHPGQISFPGGKIEPSDSSAITAA
LREAEEEIGLCRENVEVIGTFPAHNTFTGFEITPVVGMIKQDFALRLDPGEVADCFTVPLSFFIEPQNRHRKQFLRQGRY
YSVHFIPYQQRFIWGATAAIIDHLCRHLSLPEEML

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=168, Percent_Identity=37.5, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788115, Length=165, Percent_Identity=43.030303030303, Blast_Score=109, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17536993, Length=118, Percent_Identity=38.9830508474576, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17510677, Length=156, Percent_Identity=34.6153846153846, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323180, Length=216, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859683, Length=170, Percent_Identity=41.1764705882353, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22048; Mature: 22048

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQAEFRLRFNLHPLATQDPAAIPHLGLRKAAVLIPLQEIQGELSLILTQRPMHLRAHPG
CCCCCEEEEEECCCCCCCCCCCCCCCCCCHHEEEEEHHHHCCCEEEEEECCCCEEEECCC
QISFPGGKIEPSDSSAITAALREAEEEIGLCRENVEVIGTFPAHNTFTGFEITPVVGMIK
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHH
QDFALRLDPGEVADCFTVPLSFFIEPQNRHRKQFLRQGRYYSVHFIPYQQRFIWGATAAI
CCCEEEECCCCHHHHHEECCCEEECCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHH
IDHLCRHLSLPEEML
HHHHHHHCCCCHHCC
>Mature Secondary Structure
MDQAEFRLRFNLHPLATQDPAAIPHLGLRKAAVLIPLQEIQGELSLILTQRPMHLRAHPG
CCCCCEEEEEECCCCCCCCCCCCCCCCCCHHEEEEEHHHHCCCEEEEEECCCCEEEECCC
QISFPGGKIEPSDSSAITAALREAEEEIGLCRENVEVIGTFPAHNTFTGFEITPVVGMIK
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHH
QDFALRLDPGEVADCFTVPLSFFIEPQNRHRKQFLRQGRYYSVHFIPYQQRFIWGATAAI
CCCEEEECCCCHHHHHEECCCEEECCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHH
IDHLCRHLSLPEEML
HHHHHHHCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA