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The map label for this gene is asnC [H]

Identifier: 117920749

GI number: 117920749

Start: 2770524

End: 2771924

Strand: Direct

Name: asnC [H]

Synonym: Shewana3_2306

Alternate gene names: 117920749

Gene position: 2770524-2771924 (Clockwise)

Preceding gene: 117920747

Following gene: 117920750

Centisome position: 55.72

GC content: 50.61

Gene sequence:

>1401_bases
ATGAGCATTGCATCGGTCGCTTCTGTATTTAAAGGTGAGCACGCAGTTGGTTCGACAGTCACAGTCCGTGGCTGGGTCAG
AACCCGTCGTGACTCGAAAGCTGGCATCTCTTTTTTAGCTGTCTATGACGGCTCCTGCTTTAATCCTATTCAAGGTGTTG
TGCCAAATAGCTTAGAAAATTACGACAACGAAGTGTTAAAGCTGACAGCTGGCTGCTCTGTGATCGTAACCGGTGAGATT
GTGGAATCTCCTGGCGCTGGCCAAGCCTACGAGCTGCAAGTCACACACGTTGAAGTGACGGGTTGGGTCGAAGATCCAGA
CACTTACCCAATGGCGGCTAAGCGTCACTCAATCGAGCATTTACGCGAACTGGCCCACTTACGCCCACGTACCAACATCA
TTGGTGCCGTTGCCCGCGTACGTAACTGTTTGTCTCAAGCGATTCACCGTTTCTACCACGAAAATGGTTTCGTGTGGGTA
TCTACACCGCTGATCACCGCATCAGACTGTGAAGGCGCGGGTGAAATGTTCCGTGTCTCCACACTGGACATGGAAAACCT
GCCACGCACCAGCGATGGCAAAGTAGACTATGACAAAGACTTCTTCGGTAAAGAGGCATTCTTAACCGTATCGGGCCAGT
TGAACGGCGAAACCTACGCCTGTGCCCTGTCAAAAATCTATACCTTTGGCCCGACGTTCCGTGCTGAAAACTCAAACACC
AGCCGCCACTTAGCGGAATTCTGGATGGTTGAGCCTGAAGTGGCGTTCGCGACCTTAAGCGATATCGCAAGCCTTGCCGA
AGGCATGCTGAAATACGCCTTTAACGCCGTATTAGCTGAACGTATGGACGATTTACAATTCTTCGCCCAGCACGTGGATA
AAACCGTGATTGAGCGTCTGCAGTCTTTCGTATCGAGTGATTTCGCCCAGGTAGATTACACAGATGCAGTAGACATTCTG
CAAAAATGTGGTCGTGAGTTCGAATTCCCAGTGTCTTGGGGTATCGACTTATCCTCTGAGCACGAGCGTTATCTGGCCGA
AGAGCACTTCAAAGCCCCTGTGGTTGTGAAGAACTATCCAAAAGATATCAAAGCCTTCTACATGCGCCTTAACGAAGACG
GTAAAACCGTTGCCGCGATGGACGTGTTAGCCCCAGGCATAGGTGAAATCATCGGTGGTTCACAACGTGAAGAGCGTTTA
GACGTGCTGGATATGCGTTTAGAAGAAATGGATCTGAATAAAGAAGATTACTGGTGGTATCGCGATCTGCGCCGTTACGG
CACAGTGCCACACTCAGGTTTCGGTCTGGGCTTCGAGCGTTTGGTGTCTTACGTAACGGGCGTATCGAACATCCGTGACG
TGATCCCATTCCCACGCGCGCCACGCACTGCGAACTTCTAA

Upstream 100 bases:

>100_bases
CCTCAGGATACCTTTTTCAGCTTGAGAAAAGCCACCAGCAAGGTAATATAAACCTCCAAAAATTTTCATATAAAACGTTT
CGTTGGAGAACTAAGCAACA

Downstream 100 bases:

>100_bases
TTTGTCCGTTAACAGACACATCCTTTAAAACGCGCCTCGGCGCGTTTTTTATTGCCCTGTAAAAATGCGTTAAAATTCAT
CACTCGGTCAAACTCCTTCG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSIASVASVFKGEHAVGSTVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVIVTGEI
VESPGAGQAYELQVTHVEVTGWVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFVWV
STPLITASDCEGAGEMFRVSTLDMENLPRTSDGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFATLSDIASLAEGMLKYAFNAVLAERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDIL
QKCGREFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLEEMDLNKEDYWWYRDLRRYGTVPHSGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF

Sequences:

>Translated_466_residues
MSIASVASVFKGEHAVGSTVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVIVTGEI
VESPGAGQAYELQVTHVEVTGWVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFVWV
STPLITASDCEGAGEMFRVSTLDMENLPRTSDGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFATLSDIASLAEGMLKYAFNAVLAERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDIL
QKCGREFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLEEMDLNKEDYWWYRDLRRYGTVPHSGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
>Mature_465_residues
SIASVASVFKGEHAVGSTVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLENYDNEVLKLTAGCSVIVTGEIV
ESPGAGQAYELQVTHVEVTGWVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFVWVS
TPLITASDCEGAGEMFRVSTLDMENLPRTSDGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFATLSDIASLAEGMLKYAFNAVLAERMDDLQFFAQHVDKTVIERLQSFVSSDFAQVDYTDAVDILQ
KCGREFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDMRLEEMDLNKEDYWWYRDLRRYGTVPHSGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=41.5948275862069, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=28.5714285714286, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI45439306, Length=354, Percent_Identity=27.683615819209, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=80.6866952789699, Blast_Score=806, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556372, Length=429, Percent_Identity=30.3030303030303, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71984122, Length=450, Percent_Identity=30.2222222222222, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17551876, Length=340, Percent_Identity=27.6470588235294, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319872, Length=487, Percent_Identity=35.9342915811088, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=464, Percent_Identity=30.3879310344828, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=478, Percent_Identity=24.2677824267782, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=35.9913793103448, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI19921528, Length=479, Percent_Identity=28.39248434238, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI17136276, Length=341, Percent_Identity=26.6862170087977, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52261; Mature: 52130

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASVASVFKGEHAVGSTVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLEN
CCHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCHHHH
YDNEVLKLTAGCSVIVTGEIVESPGAGQAYELQVTHVEVTGWVEDPDTYPMAAKRHSIEH
HCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFVWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTSDGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFATLSDIASLAEGMLKYAFNAVLAERMDDLQFFAQHVDKTVIERL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVDILQKCGREFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLEEMDLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIASVASVFKGEHAVGSTVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLEN
CHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCHHHH
YDNEVLKLTAGCSVIVTGEIVESPGAGQAYELQVTHVEVTGWVEDPDTYPMAAKRHSIEH
HCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFVWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTSDGKVDYDKDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFATLSDIASLAEGMLKYAFNAVLAERMDDLQFFAQHVDKTVIERL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVDILQKCGREFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLEEMDLNKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHSGFGLGFERLVSYVTGVSNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA