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The map label for this gene is pabB [H]

Identifier: 117920746

GI number: 117920746

Start: 2767996

End: 2769399

Strand: Direct

Name: pabB [H]

Synonym: Shewana3_2303

Alternate gene names: 117920746

Gene position: 2767996-2769399 (Clockwise)

Preceding gene: 117920741

Following gene: 117920747

Centisome position: 55.67

GC content: 52.07

Gene sequence:

>1404_bases
ATGGCAAATAGGGCGGCATTACCGCTGGCAGTACGCCAACTTGACTGGACTTTCAGCACAGCAGCAATCTTCGAATACTT
TGCGGCAGAACCTTGGGCCATATTGCTCGACTCGGCCAATGCGCCCCATCAGGACGCTAAATTCGATATGATTTGCGCAG
GTCCCATTGCCACCCTCATCACCCAAGGCGAACTGACTGACATTCAAGTTCATCAGCCTGAATTAACCAAACCGACTCAC
CTCTGCCCGCAGGATGACCCTTTTACCCTGGTCAAACAGCTGCTGCGCCATTGGTATCCACACTCTTTTGCCTGCGATTT
GCCCTTTAGTGGCGGCGCCATGGGCAGCTTTAGTTATGACTTAGGCCGCCGGATTGAGCAGCTCCCGAGCACAGCAGCGC
ATGATATTCACCTCGGCGAGATGAATATTGGCTTTTACGACTGGGCATTGATTTTCGATTATCAGCAGCAAAGCTGGTTT
ATGGTGCACTATTTGGGGGATGCCGTCCTCGATACTCAATTGAAAATAATTGAAGCAAAAATAGCCAAACCCACAAAGCA
GGCCGAATTTCGTCTCACAAGCCCTTGGTCGGCGCAGACCACCAAAGCCCAGTACGCCGCAAAATTTACTCAAGTACAGG
CGTATCTGCATAGCGGCGATTGCTATCAAATTAATTTAACCCAGCGCTTTGAAGCAGAGTATCAAGGCGATGAATGGCGC
GCTTACTGCAAGCTACGAAGTGCCAATCAAGCGCCCTTCTCCGCCTTTATGCGGCTTGATGCCAACGCGATTTTATCGAT
TTCGCCCGAGCGTTTTATTCAGCTACGCGGTGACGACATTCAAACCAAACCGATTAAAGGCACGCTGCCGCGCCATAGCG
ACCCGATGCTAGATAAGCAAGCAGCGCAAGCCCTTGCCCATTCGCCCAAGGATCGCGCCGAAAACGTGATGATTGTGGAT
TTACTGCGCAATGACATAGGTAAAGTCGCGGCGCCCGGCACTGTACAAGTGCCACATCTATTTGCCGTTGAAAGCTTTCC
TGCGGTGCACCATTTAGTCAGTACCGTCACGGCCAAACTCGACCCACATTACCACGCCTGCGACTTGTTGCGGGCGGCCT
TTCCCGGCGGTTCAATAACCGGTGCGCCTAAAATCCGCGCCATGGAAATTATTGAAGAGCTGGAACCCTCACGCCGCAGT
CTGTATTGTGGCTCCATGGGGTATATCAGCCAAGATGGGCAAATGGACACCAGTATCACCATCCGCACTATCGTGGCAGA
GCAAGGTAAACTCTATTGCTGGGCGGGCGGCGGCATAGTCGCGGACTCTAATGTCGATGCCGAGTACCAAGAAAGCTTCG
ATAAGATAAGCCGCATCTTACCCTTGCTCGATAGCCCTCAATAA

Upstream 100 bases:

>100_bases
TTTAGGGCCTTACTTGTTTTTTGTGTAATTCTTTCTGGGCCAATATGATACTCTTTCCCATCTTTTTGGGCTACATCACA
TTTTTAGATAGGGTTAATTG

Downstream 100 bases:

>100_bases
GCGTCAGGAAACGAATAGGAAGCCAATGGATCAAGCGGAATTTAGACTCAGATTTAATCTGCATCCTTTAGCCACGCAAG
ATCCGGCGGCTATCCCTCAC

Product: aminodeoxychorismate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MANRAALPLAVRQLDWTFSTAAIFEYFAAEPWAILLDSANAPHQDAKFDMICAGPIATLITQGELTDIQVHQPELTKPTH
LCPQDDPFTLVKQLLRHWYPHSFACDLPFSGGAMGSFSYDLGRRIEQLPSTAAHDIHLGEMNIGFYDWALIFDYQQQSWF
MVHYLGDAVLDTQLKIIEAKIAKPTKQAEFRLTSPWSAQTTKAQYAAKFTQVQAYLHSGDCYQINLTQRFEAEYQGDEWR
AYCKLRSANQAPFSAFMRLDANAILSISPERFIQLRGDDIQTKPIKGTLPRHSDPMLDKQAAQALAHSPKDRAENVMIVD
LLRNDIGKVAAPGTVQVPHLFAVESFPAVHHLVSTVTAKLDPHYHACDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRS
LYCGSMGYISQDGQMDTSITIRTIVAEQGKLYCWAGGGIVADSNVDAEYQESFDKISRILPLLDSPQ

Sequences:

>Translated_467_residues
MANRAALPLAVRQLDWTFSTAAIFEYFAAEPWAILLDSANAPHQDAKFDMICAGPIATLITQGELTDIQVHQPELTKPTH
LCPQDDPFTLVKQLLRHWYPHSFACDLPFSGGAMGSFSYDLGRRIEQLPSTAAHDIHLGEMNIGFYDWALIFDYQQQSWF
MVHYLGDAVLDTQLKIIEAKIAKPTKQAEFRLTSPWSAQTTKAQYAAKFTQVQAYLHSGDCYQINLTQRFEAEYQGDEWR
AYCKLRSANQAPFSAFMRLDANAILSISPERFIQLRGDDIQTKPIKGTLPRHSDPMLDKQAAQALAHSPKDRAENVMIVD
LLRNDIGKVAAPGTVQVPHLFAVESFPAVHHLVSTVTAKLDPHYHACDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRS
LYCGSMGYISQDGQMDTSITIRTIVAEQGKLYCWAGGGIVADSNVDAEYQESFDKISRILPLLDSPQ
>Mature_466_residues
ANRAALPLAVRQLDWTFSTAAIFEYFAAEPWAILLDSANAPHQDAKFDMICAGPIATLITQGELTDIQVHQPELTKPTHL
CPQDDPFTLVKQLLRHWYPHSFACDLPFSGGAMGSFSYDLGRRIEQLPSTAAHDIHLGEMNIGFYDWALIFDYQQQSWFM
VHYLGDAVLDTQLKIIEAKIAKPTKQAEFRLTSPWSAQTTKAQYAAKFTQVQAYLHSGDCYQINLTQRFEAEYQGDEWRA
YCKLRSANQAPFSAFMRLDANAILSISPERFIQLRGDDIQTKPIKGTLPRHSDPMLDKQAAQALAHSPKDRAENVMIVDL
LRNDIGKVAAPGTVQVPHLFAVESFPAVHHLVSTVTAKLDPHYHACDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSL
YCGSMGYISQDGQMDTSITIRTIVAEQGKLYCWAGGGIVADSNVDAEYQESFDKISRILPLLDSPQ

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=457, Percent_Identity=54.9234135667396, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1787518, Length=422, Percent_Identity=27.9620853080569, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786809, Length=201, Percent_Identity=27.363184079602, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082077, Length=219, Percent_Identity=25.5707762557078, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=445, Percent_Identity=31.0112359550562, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324361, Length=401, Percent_Identity=27.431421446384, Blast_Score=148, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 52089; Mature: 51958

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRAALPLAVRQLDWTFSTAAIFEYFAAEPWAILLDSANAPHQDAKFDMICAGPIATLI
CCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
TQGELTDIQVHQPELTKPTHLCPQDDPFTLVKQLLRHWYPHSFACDLPFSGGAMGSFSYD
CCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHH
LGRRIEQLPSTAAHDIHLGEMNIGFYDWALIFDYQQQSWFMVHYLGDAVLDTQLKIIEAK
HHHHHHHCCCCCCCEEEECCEECCEEEEEEEEEECCCCEEEEEECCCHHHHHHHHEEHHH
IAKPTKQAEFRLTSPWSAQTTKAQYAAKFTQVQAYLHSGDCYQINLTQRFEAEYQGDEWR
HCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHEECCCEEEEEEHHEECCCCCCCCEE
AYCKLRSANQAPFSAFMRLDANAILSISPERFIQLRGDDIQTKPIKGTLPRHSDPMLDKQ
EEEEECCCCCCHHHHHHHCCCCEEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHH
AAQALAHSPKDRAENVMIVDLLRNDIGKVAAPGTVQVPHLFAVESFPAVHHLVSTVTAKL
HHHHHHCCCHHHHCCEEEEEHHHHHHHCCCCCCCEECCEEEEECCCHHHHHHHHHHHHHC
DPHYHACDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGSMGYISQDGQMDTSIT
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCEEE
IRTIVAEQGKLYCWAGGGIVADSNVDAEYQESFDKISRILPLLDSPQ
EEEEEECCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ANRAALPLAVRQLDWTFSTAAIFEYFAAEPWAILLDSANAPHQDAKFDMICAGPIATLI
CCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHH
TQGELTDIQVHQPELTKPTHLCPQDDPFTLVKQLLRHWYPHSFACDLPFSGGAMGSFSYD
CCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHH
LGRRIEQLPSTAAHDIHLGEMNIGFYDWALIFDYQQQSWFMVHYLGDAVLDTQLKIIEAK
HHHHHHHCCCCCCCEEEECCEECCEEEEEEEEEECCCCEEEEEECCCHHHHHHHHEEHHH
IAKPTKQAEFRLTSPWSAQTTKAQYAAKFTQVQAYLHSGDCYQINLTQRFEAEYQGDEWR
HCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHEECCCEEEEEEHHEECCCCCCCCEE
AYCKLRSANQAPFSAFMRLDANAILSISPERFIQLRGDDIQTKPIKGTLPRHSDPMLDKQ
EEEEECCCCCCHHHHHHHCCCCEEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHH
AAQALAHSPKDRAENVMIVDLLRNDIGKVAAPGTVQVPHLFAVESFPAVHHLVSTVTAKL
HHHHHHCCCHHHHCCEEEEEHHHHHHHCCCCCCCEECCEEEEECCCHHHHHHHHHHHHHC
DPHYHACDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGSMGYISQDGQMDTSIT
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCCEEE
IRTIVAEQGKLYCWAGGGIVADSNVDAEYQESFDKISRILPLLDSPQ
EEEEEECCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]