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The map label for this gene is hypB [H]

Identifier: 117920316

GI number: 117920316

Start: 2214932

End: 2215693

Strand: Reverse

Name: hypB [H]

Synonym: Shewana3_1871

Alternate gene names: 117920316

Gene position: 2215693-2214932 (Counterclockwise)

Preceding gene: 117920317

Following gene: 117920315

Centisome position: 44.56

GC content: 49.87

Gene sequence:

>762_bases
ATGTGTAAAGACTGCGGCTGCTCCTTACCCCGCCATTCACATGAACACGGCCATCTGCATCACCATCAGGAATTGCACAC
CAATCCTCAGCTTAACGATAAAAAAACCTTGTCGGTGATCCACAAAATTCTCGATAAAAACGATGTCGAAGCGGCCCATA
ACCGTGCGCATTTTGAGGCGCACAATATCACTGCCTTCAATTTAATGAGTAGCCCAGGCAGTGGCAAAACCACCTTGCTC
GAACACTTAAAAGAGTACACCACCCTCAACTACGCCGTAATTGAAGGGGATTTAGAGACCTCCCGCGATGCCGACCGCTT
AATCGCCAAAGGCATTCAGGCCCATCAAATTCAAACGGGCAGTGCCTGCCACCTCGACGCATTCATGGTGCATGGCGCTT
TGCATCACTTGCCACTCGAAGGCTTAGATATTTGCTTTGTCGAAAACGTGGGAAACCTCGTCTGCCCCGCCAGTTATGAT
GTCGGCACCCATAAAAATATCGTGCTGCTCTCGGTTCCCGAAGGCGATGATAAGATTGAGAAATATCCAGTGATGTTCCG
CCGTGCCGATCTGGTGCTCATCACCAAATGTGACCTCTTGCCCTACTTCGATTTCAGTGTTGACGAGGCGAAAGCTCAAC
TTAAAAAGCTCAACCCCAACACACAAATTCTGGAAGTCTCCATTAAGGATGGCGATGCCATGCGTGCCGTCGTTGCATGG
CTGAACGATAACCTTCACCACGCTGCGGGAGAGCCACAATAA

Upstream 100 bases:

>100_bases
ACATTAGCGTAATCAAATTAACCCTATTCGATAGCATCAGCATATTGTCAGGCAAATGCGCCCAAAGAGGCGCTCGGCCT
AGGACAAGGAGAAATATAAG

Downstream 100 bases:

>100_bases
TGTGCCTGTCTATTCCTTCCCAAGTTGTGGCCGTGGATAACGAGCGTCAATCGGTCACCGTCGATACCTTAGGCGTCAGG
CGCGATGTGAGCAGCCATTT

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MCKDCGCSLPRHSHEHGHLHHHQELHTNPQLNDKKTLSVIHKILDKNDVEAAHNRAHFEAHNITAFNLMSSPGSGKTTLL
EHLKEYTTLNYAVIEGDLETSRDADRLIAKGIQAHQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYD
VGTHKNIVLLSVPEGDDKIEKYPVMFRRADLVLITKCDLLPYFDFSVDEAKAQLKKLNPNTQILEVSIKDGDAMRAVVAW
LNDNLHHAAGEPQ

Sequences:

>Translated_253_residues
MCKDCGCSLPRHSHEHGHLHHHQELHTNPQLNDKKTLSVIHKILDKNDVEAAHNRAHFEAHNITAFNLMSSPGSGKTTLL
EHLKEYTTLNYAVIEGDLETSRDADRLIAKGIQAHQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYD
VGTHKNIVLLSVPEGDDKIEKYPVMFRRADLVLITKCDLLPYFDFSVDEAKAQLKKLNPNTQILEVSIKDGDAMRAVVAW
LNDNLHHAAGEPQ
>Mature_253_residues
MCKDCGCSLPRHSHEHGHLHHHQELHTNPQLNDKKTLSVIHKILDKNDVEAAHNRAHFEAHNITAFNLMSSPGSGKTTLL
EHLKEYTTLNYAVIEGDLETSRDADRLIAKGIQAHQIQTGSACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYD
VGTHKNIVLLSVPEGDDKIEKYPVMFRRADLVLITKCDLLPYFDFSVDEAKAQLKKLNPNTQILEVSIKDGDAMRAVVAW
LNDNLHHAAGEPQ

Specific function: Plays a role in both the hydrogenase and the urease nickel cofactor insertion step [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=231, Percent_Identity=45.8874458874459, Blast_Score=193, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 28171; Mature: 28171

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKDCGCSLPRHSHEHGHLHHHQELHTNPQLNDKKTLSVIHKILDKNDVEAAHNRAHFEA
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCEEEE
HNITAFNLMSSPGSGKTTLLEHLKEYTTLNYAVIEGDLETSRDADRLIAKGIQAHQIQTG
CCEEEEEEECCCCCCHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHCCCHHEEECCC
SACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPEGDDKIE
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEECCCCCCHHH
KYPVMFRRADLVLITKCDLLPYFDFSVDEAKAQLKKLNPNTQILEVSIKDGDAMRAVVAW
HCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHH
LNDNLHHAAGEPQ
HCCCCCCCCCCCC
>Mature Secondary Structure
MCKDCGCSLPRHSHEHGHLHHHQELHTNPQLNDKKTLSVIHKILDKNDVEAAHNRAHFEA
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCEEEE
HNITAFNLMSSPGSGKTTLLEHLKEYTTLNYAVIEGDLETSRDADRLIAKGIQAHQIQTG
CCEEEEEEECCCCCCHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHCCCHHEEECCC
SACHLDAFMVHGALHHLPLEGLDICFVENVGNLVCPASYDVGTHKNIVLLSVPEGDDKIE
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEECCCCCCHHH
KYPVMFRRADLVLITKCDLLPYFDFSVDEAKAQLKKLNPNTQILEVSIKDGDAMRAVVAW
HCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHH
LNDNLHHAAGEPQ
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]