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The map label for this gene is hypA [H]

Identifier: 117920312

GI number: 117920312

Start: 2212121

End: 2212477

Strand: Reverse

Name: hypA [H]

Synonym: Shewana3_1867

Alternate gene names: 117920312

Gene position: 2212477-2212121 (Counterclockwise)

Preceding gene: 117920313

Following gene: 117920307

Centisome position: 44.5

GC content: 52.38

Gene sequence:

>357_bases
ATGCACGAATATTCCATCGTCAGCGCCTTGATTGAGCAATGCGAGCAACACGCTAGGGCTAATCGAGCCAATAAAATCAC
CCGCGTCGATATCAAACTCGGCGTGATGAGCGGGGTCGAACCCACCTTGCTCGAGACCGCCTTTGAAACCTTTAAACTCG
ATGGGCTCTGCCGTGATGCTGAACTGCGAATGACGCTGCAACCCTTAGTGATTGCCTGTTTGGATTGCCACCAAGAGTCT
GAGCTTGCTGAGCGCTCTATCGTCTGCCCTGCGTGTCACAGCTACCACACGCGGGTATTAGATGGCGAAGATATGCTACT
GATGCAGCTTGAAATGGAGCAAGAAGACGAGCGCTAA

Upstream 100 bases:

>100_bases
TGAGCGACGAACTTCAAGGAAAAGTGATCTTAAGAACGCCATGGAATACCAAACGTTACTTAGACTTGCCCCAGGGTGAA
CTGCTGCCAAGGATTTGTTA

Downstream 100 bases:

>100_bases
GTGGCTGTAAGCCTCTGACTTAAGCATTCACACTTGATATAAAATGGGCTTTAAGTATCCACTTAAAGCCCATTTTATTG
GTCTGCTAGCAGCCACTTTC

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MHEYSIVSALIEQCEQHARANRANKITRVDIKLGVMSGVEPTLLETAFETFKLDGLCRDAELRMTLQPLVIACLDCHQES
ELAERSIVCPACHSYHTRVLDGEDMLLMQLEMEQEDER

Sequences:

>Translated_118_residues
MHEYSIVSALIEQCEQHARANRANKITRVDIKLGVMSGVEPTLLETAFETFKLDGLCRDAELRMTLQPLVIACLDCHQES
ELAERSIVCPACHSYHTRVLDGEDMLLMQLEMEQEDER
>Mature_118_residues
MHEYSIVSALIEQCEQHARANRANKITRVDIKLGVMSGVEPTLLETAFETFKLDGLCRDAELRMTLQPLVIACLDCHQES
ELAERSIVCPACHSYHTRVLDGEDMLLMQLEMEQEDER

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=26.5486725663717, Blast_Score=59, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR004039 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13463; Mature: 13463

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
10.2 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
10.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEYSIVSALIEQCEQHARANRANKITRVDIKLGVMSGVEPTLLETAFETFKLDGLCRDA
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
ELRMTLQPLVIACLDCHQESELAERSIVCPACHSYHTRVLDGEDMLLMQLEMEQEDER
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MHEYSIVSALIEQCEQHARANRANKITRVDIKLGVMSGVEPTLLETAFETFKLDGLCRDA
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
ELRMTLQPLVIACLDCHQESELAERSIVCPACHSYHTRVLDGEDMLLMQLEMEQEDER
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA