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The map label for this gene is hypE [H]

Identifier: 117920313

GI number: 117920313

Start: 2212477

End: 2213496

Strand: Reverse

Name: hypE [H]

Synonym: Shewana3_1868

Alternate gene names: 117920313

Gene position: 2213496-2212477 (Counterclockwise)

Preceding gene: 117920314

Following gene: 117920312

Centisome position: 44.52

GC content: 52.65

Gene sequence:

>1020_bases
ATGGCTGATTTCCAACCCAAAGATAAAGCGATTCAACTCAGCCACGGTGGTGGCGGCAAAGAGATGAACAAACTTATTCG
TGAACTGTTTTTTACCGAGTTCGATAACCCCATCCTGCGCAGCGAAGAAGACGCAGCCAAGCTCGATCTGCAAGGCGCCA
CCGCCTTTACCACTGATTCCTTTACCGTATCACCGCTGTTTTTTGCTGGCGGAGATATTGGCAAGTTAGCGATCGCCGGT
ACTGTGAATGATCTTGCCATGATGGGCGCCGAGCCACAGTATTTAAGTTGCAGTGTGATCATCGAAGAAGGCTTTTCGCT
CAATCAGTTAACCACTATTGTGCGCAGCATGGCGAAGGAGCTTAAACAGAGCGGCGCCAGAATCGTTTGTGGCGATACCA
AGGTCGTACCTAAGGGCTGCGCCGATGGCTTGTTTATCAATACCTCCGGCGTTGGACGGATTTTACGTCCGAATATCTCG
GCGGCGAATGTCGCGCCGGGGGATGCAATCATTGTTTCCCGCGATGTGGGCTGCCATGGCGCCGCGATTCTGATGGCGCG
CGAAGGCCTAACCCTCGAATCGGCTTTACAAAGCGATTGTGCCACCCTTTGGCCCGTGGTTGAGCAGCTTATTGCGGCGA
ATATTCCCATTCATGCGATGCGTGATGCAACTCGTGGTGGGCTGTCTGCCGTATTAAACGAGTGGGCGGCGGCCGCCAAT
GTCGGGATTACCGTCAACGAAGCCAGTATTCCGGTTTGCGATGAAGTCAAAGGCTTGTGCGAGCTCTATGGCTTTGAGGC
CATGGATTTAGCCAATGAAGGCACCTTTATCTTGGCGGTCCCTAACGATATCGCCCTTGGCGCCTTGGAAATCATGCAGC
GCTTTGGTCATTGCGAGCAGGCAGCCATCATCGGCACGGTGAGCGACGAACTTCAAGGAAAAGTGATCTTAAGAACGCCA
TGGAATACCAAACGTTACTTAGACTTGCCCCAGGGTGAACTGCTGCCAAGGATTTGTTAA

Upstream 100 bases:

>100_bases
TGCAATCCCGAAACCCCTCTCGGTAGCTGTATGGTTAGCTCCGAAGGCGCGTGTAATGCGTATTACCGCTATCAAGGCAT
AGATAGCAAGGAGCCACACC

Downstream 100 bases:

>100_bases
TGCACGAATATTCCATCGTCAGCGCCTTGATTGAGCAATGCGAGCAACACGCTAGGGCTAATCGAGCCAATAAAATCACC
CGCGTCGATATCAAACTCGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MADFQPKDKAIQLSHGGGGKEMNKLIRELFFTEFDNPILRSEEDAAKLDLQGATAFTTDSFTVSPLFFAGGDIGKLAIAG
TVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGVGRILRPNIS
AANVAPGDAIIVSRDVGCHGAAILMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAAN
VGITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQAAIIGTVSDELQGKVILRTP
WNTKRYLDLPQGELLPRIC

Sequences:

>Translated_339_residues
MADFQPKDKAIQLSHGGGGKEMNKLIRELFFTEFDNPILRSEEDAAKLDLQGATAFTTDSFTVSPLFFAGGDIGKLAIAG
TVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGVGRILRPNIS
AANVAPGDAIIVSRDVGCHGAAILMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAAN
VGITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQAAIIGTVSDELQGKVILRTP
WNTKRYLDLPQGELLPRIC
>Mature_338_residues
ADFQPKDKAIQLSHGGGGKEMNKLIRELFFTEFDNPILRSEEDAAKLDLQGATAFTTDSFTVSPLFFAGGDIGKLAIAGT
VNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGVGRILRPNISA
ANVAPGDAIIVSRDVGCHGAAILMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAANV
GITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQAAIIGTVSDELQGKVILRTPW
NTKRYLDLPQGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=47.3372781065089, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36079; Mature: 35948

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFQPKDKAIQLSHGGGGKEMNKLIRELFFTEFDNPILRSEEDAAKLDLQGATAFTTDS
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHCCCCCHHEEEECCCEEEECCC
FTVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKE
EEECEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHH
LKQSGARIVCGDTKVVPKGCADGLFINTSGVGRILRPNISAANVAPGDAIIVSRDVGCHG
HHHCCCEEEECCCEECCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEEECCCCCC
AAILMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAAN
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCC
VGITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQ
CCEEEECCCCCHHHHHHHHHHHHCCHHEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCC
AAIIGTVSDELQGKVILRTPWNTKRYLDLPQGELLPRIC
EEEEEEECHHHCCEEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
ADFQPKDKAIQLSHGGGGKEMNKLIRELFFTEFDNPILRSEEDAAKLDLQGATAFTTDS
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHCCCCCHHEEEECCCEEEECCC
FTVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKE
EEECEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHH
LKQSGARIVCGDTKVVPKGCADGLFINTSGVGRILRPNISAANVAPGDAIIVSRDVGCHG
HHHCCCEEEECCCEECCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCEEEEEECCCCCC
AAILMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAAN
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCC
VGITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQ
CCEEEECCCCCHHHHHHHHHHHHCCHHEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCC
AAIIGTVSDELQGKVILRTPWNTKRYLDLPQGELLPRIC
EEEEEEECHHHCCEEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]