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The map label for this gene is hlyB [H]

Identifier: 117920307

GI number: 117920307

Start: 2205283

End: 2206800

Strand: Reverse

Name: hlyB [H]

Synonym: Shewana3_1862

Alternate gene names: 117920307

Gene position: 2206800-2205283 (Counterclockwise)

Preceding gene: 117920312

Following gene: 117920306

Centisome position: 44.38

GC content: 50.2

Gene sequence:

>1518_bases
ATGAAAGAAGTAAAATTTCGCTGGATAGATCAATATCTTATCCACATGACCTTAAAAACCAAATTTGCAATTCTCGCCCT
AGTTCCCATGTTTATGATTGTGGGATTAGCGGTATTTTTAAATACTCAGTTTAGGGATACCCTGCTCGAAAGCCATTTGA
ACGGCATTCAGGACTCGTCACAGAAAATCAATCAACTCGCGGCGCAGATCTATAACAAACTGCCCGAACAAGAACAGCAA
AATCTCCCTAATCTATTAAGCCAAGGGATGCAGAATGTTCGGATTGTCACGGTTTCAGAGGCCGACAGCCGCGCACAAAC
CCTTGCACGCAGTGGCGGAGGTATCGATACCAGCAGTTCACCTCAAAGGGCGATAAGCTCGGTTAACGCTCAAAACCTCG
TCACTATCATTCCCGTCGACGATCGCGCAATTGATGCCCTGCTGGCCGACGACAACATCTTAGTTTATGGCGTGATGGCA
GTGCTGTTATTCGTGCTCTTCCTGTTTAGCTACTACATCTCCACCTTTGTGGGCGGTGCGCTCTACACCACAGTGATGGC
ACTTAAACGCGCCGCCTCGGGGGATTTGACTGGCCGATTAAACTTCTTCGAAGTGAAAGATGAGTTCAGCATTTTAGCGA
TTAGTATCGACACCTTGGTCGAGCGTCAACATACCCTAGTGAAGCAAATTGCTGAATCCACCAGCAAAATCCGCGAAGTG
GTTTCATCATTTAGAAGCACGGCGCAGCAAGGACAAGCCCTTGCGGTCAATCAACGTCAGCACCTCGATTCCTTAGCCAC
AGCGATGGAAGAAATGACCGCTGCGGTTAAAGAAGTGGCGCGCAACGCCGAGCAATCCTCCGCCGAAACCCAAGAGGCGA
ATCAGCAGGTCAATGCGGGCTCTAAGGATATTGAAACCACAGTGAGCGCGATTGATGTGCTATCGGATGAGATTTCTGCC
GCCTCGGATGCGGTCAATATCCTCAACGAAAACGCCAGTAAAATCGATGAAGTAGTGTCGACCATTAATGCCATTTCGCA
GCAGACTAACCTACTCGCCCTCAATGCTGCGATTGAAGCGGCGCGCGCGGGCGAACAGGGCCGTGGCTTTGCGGTGGTGG
CCGATGAGGTGAGAACCCTTGCTGGTCGCACTCAGGCGGCAACGGTTGAAATCAAGTCGATGATCGAGTCATTGCAACAG
GGGAGCCGTAACCTGACGCAAGTCATGTCTCGCACGGTAAGCCAAGCGAGTGAAGGCAAACAACATGTGCTGCAAACGGG
TAAGGATCTCGAATCCATTGCCCACCACAGCAGCCGCGTATTTGAAATGAGTGTATTGATCGCAACGTCTGCGGAAGAAC
AATCGGCCGTGGCTAACGAAATCGCCACCAATCTGATGGAAATTCGCAATCAATCCCACGATGTCGAGCAATCGGCGAAC
CAATCTGTGTCGGGTTGTGATGAATTACAAGCCACCGCTGGCCAACTCGATCAGTTAATGGTTGGACTTAAGGTCTAA

Upstream 100 bases:

>100_bases
AACAATAATACAAGCAACTGCTTACAAGACAGAAAATCATAAAGTCTATGGCAAACCGACCGATATCCATTTGGTCACAG
CCCAATTTATCGAGGCGCTA

Downstream 100 bases:

>100_bases
TACTGAAAAGTGAGTGTCGAGTAATAGTCGAGTAATAGATGAAGGGATAACGCTTATCCCTTCATCTATATGTTTCTATA
GCCTCTCCTAGATTTATGAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MKEVKFRWIDQYLIHMTLKTKFAILALVPMFMIVGLAVFLNTQFRDTLLESHLNGIQDSSQKINQLAAQIYNKLPEQEQQ
NLPNLLSQGMQNVRIVTVSEADSRAQTLARSGGGIDTSSSPQRAISSVNAQNLVTIIPVDDRAIDALLADDNILVYGVMA
VLLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTSKIREV
VSSFRSTAQQGQALAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVNAGSKDIETTVSAIDVLSDEISA
ASDAVNILNENASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIESLQQ
GSRNLTQVMSRTVSQASEGKQHVLQTGKDLESIAHHSSRVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSAN
QSVSGCDELQATAGQLDQLMVGLKV

Sequences:

>Translated_505_residues
MKEVKFRWIDQYLIHMTLKTKFAILALVPMFMIVGLAVFLNTQFRDTLLESHLNGIQDSSQKINQLAAQIYNKLPEQEQQ
NLPNLLSQGMQNVRIVTVSEADSRAQTLARSGGGIDTSSSPQRAISSVNAQNLVTIIPVDDRAIDALLADDNILVYGVMA
VLLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTSKIREV
VSSFRSTAQQGQALAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVNAGSKDIETTVSAIDVLSDEISA
ASDAVNILNENASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIESLQQ
GSRNLTQVMSRTVSQASEGKQHVLQTGKDLESIAHHSSRVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSAN
QSVSGCDELQATAGQLDQLMVGLKV
>Mature_505_residues
MKEVKFRWIDQYLIHMTLKTKFAILALVPMFMIVGLAVFLNTQFRDTLLESHLNGIQDSSQKINQLAAQIYNKLPEQEQQ
NLPNLLSQGMQNVRIVTVSEADSRAQTLARSGGGIDTSSSPQRAISSVNAQNLVTIIPVDDRAIDALLADDNILVYGVMA
VLLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTSKIREV
VSSFRSTAQQGQALAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVNAGSKDIETTVSAIDVLSDEISA
ASDAVNILNENASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIESLQQ
GSRNLTQVMSRTVSQASEGKQHVLQTGKDLESIAHHSSRVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSAN
QSVSGCDELQATAGQLDQLMVGLKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=339, Percent_Identity=30.6784660766962, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=320, Percent_Identity=30, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=32.1192052980132, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788194, Length=146, Percent_Identity=44.5205479452055, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=210, Percent_Identity=32.8571428571429, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54792; Mature: 54792

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILALVPMFMIVGLAVFLNTQFRDTLLESHLNGIQDSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
QKINQLAAQIYNKLPEQEQQNLPNLLSQGMQNVRIVTVSEADSRAQTLARSGGGIDTSSS
HHHHHHHHHHHHHCCCHHHHCHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCC
PQRAISSVNAQNLVTIIPVDDRAIDALLADDNILVYGVMAVLLFVLFLFSYYISTFVGGA
HHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTSKIREV
HHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VSSFRSTAQQGQALAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVNAG
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SKDIETTVSAIDVLSDEISAASDAVNILNENASKIDEVVSTINAISQQTNLLALNAAIEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIESLQQGSRNLTQVMSRTVSQASEGK
HHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QHVLQTGKDLESIAHHSSRVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSAN
HHHHHCCHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHC
QSVSGCDELQATAGQLDQLMVGLKV
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILALVPMFMIVGLAVFLNTQFRDTLLESHLNGIQDSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHH
QKINQLAAQIYNKLPEQEQQNLPNLLSQGMQNVRIVTVSEADSRAQTLARSGGGIDTSSS
HHHHHHHHHHHHHCCCHHHHCHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCC
PQRAISSVNAQNLVTIIPVDDRAIDALLADDNILVYGVMAVLLFVLFLFSYYISTFVGGA
HHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTSKIREV
HHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VSSFRSTAQQGQALAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVNAG
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SKDIETTVSAIDVLSDEISAASDAVNILNENASKIDEVVSTINAISQQTNLLALNAAIEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIESLQQGSRNLTQVMSRTVSQASEGK
HHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QHVLQTGKDLESIAHHSSRVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSAN
HHHHHCCHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHC
QSVSGCDELQATAGQLDQLMVGLKV
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]