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The map label for this gene is gltA [H]

Identifier: 117920152

GI number: 117920152

Start: 2007512

End: 2008798

Strand: Reverse

Name: gltA [H]

Synonym: Shewana3_1705

Alternate gene names: 117920152

Gene position: 2008798-2007512 (Counterclockwise)

Preceding gene: 117920163

Following gene: 117920151

Centisome position: 40.4

GC content: 46.46

Gene sequence:

>1287_bases
ATGGCTGATTTAAAAGCCAAATTAGAATTACCAGGGAACGACTCGATAGAATTGCCAGTAAAGCAAGGATCCGCTGGTTT
TGACGTAATCGATATCAGTAAACTTGGCAGCAAGGGTTACTTCACTTTTGATCCAGGTTTTCTCGCGACAGCCTCCTGTG
AATCTGCAATTACCTATATCGATGGCGATCAAGGTATATTGTTACACCGCGGCTATCCAATCGAGCAACTCGCCGTTGAC
TCAGATTACTTAGACCTGTGTTACCTGCTGCTTTACGGTGAACTGCCGACGAAAGAGCAATATGCTGAATTTGTACACAC
AGTAAAAACCCACACTATGGTTCATGAGCAACTCGCCTTCTTCTTTAGAGGTTTCCGTCGTGATGCTCATCCTATGGCGA
TGTTATGTGGTGTTACTGGTGCATTGTCTGCATTTTATCAAGACTCACTCGATGTCAACGATCCTCGCCACCGCGAAATC
GCCGCGTATCGCCTAGTCTCCAAAATGCCAACGATTGCCGCTATGTGCTACAAGTACTCTTCTGGCCAGCCATTCGTTTA
CCCACGCAATGACTTAAGCTACGCAGGCAACTTCTTAAGCATGATGTTTGCCGTGCCTTGTGAAGAATACAAGGTAAACC
CAATCGTTGAACGTGCTATGGATCGTATCTTCATTCTACATGCGGATCACGAACAAAACGCGTCAACATCAACCGTACGT
TTAGCCGGTTCTTCAGGCGCGAATCCATTCGCGTGTATCGCTGCGGGTATTGCTTCTTTATGGGGCCCTGCACACGGCGG
CGCGAACGAAGCTTGTCTACAAATGTTAGAAGAAATCGGTTCAGTAGACCGTATTCCTGAATTCATCGCCCGTGCGAAAG
ACAAGAATGACCCATTCCGTCTAATGGGCTTCGGACACCGTGTTTACAAAAACTTTGACCCACGTGCCAAAGTGATGCGT
GAAACCTGTCACGAAGTGTTAAAAGAGCTGAAAGTACAAGATCCATTATTAGATGTGGCCATGGAACTTGAGCGTATCGC
GCTGGAAGATGAGTACTTCATTTCGAAGAAACTCTATCCAAACGTTGACTTCTACTCTGGCATCATCATGAAAGCCATTG
GTATTCCAACTAGCATGTTCACCGTACTGTTCGCATTAGCACGTACTGTGGGTTGGATTGCTCACTGGAAAGAAATGTTG
GATCAACCAGGTCACAAGATCAGCCGTCCACGTCAGCTATATACTGGCGAGACTTCGCGTGATTTCGTAAGCCAGGATAA
ACGCTAA

Upstream 100 bases:

>100_bases
AACGCTTATTTAAATTGAAATGTGATCTAGAATGGCTGTAAAGTAATGGCGGTTTGACATGCCGCACTCACAGATAAGAA
CGAAGTAAGGAGAACGGGGT

Downstream 100 bases:

>100_bases
TCGGCATTTATCGATTAAAAGCGCCCACTGGGCGCTTTTTTATTGGGATTTTCATACCCGCCCTTCGCTCTTCTTATCAC
TCCCAGCCACACAATCCCGA

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MADLKAKLELPGNDSIELPVKQGSAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYIDGDQGILLHRGYPIEQLAVD
SDYLDLCYLLLYGELPTKEQYAEFVHTVKTHTMVHEQLAFFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREI
AAYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFAVPCEEYKVNPIVERAMDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIARAKDKNDPFRLMGFGHRVYKNFDPRAKVMR
ETCHEVLKELKVQDPLLDVAMELERIALEDEYFISKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEML
DQPGHKISRPRQLYTGETSRDFVSQDKR

Sequences:

>Translated_428_residues
MADLKAKLELPGNDSIELPVKQGSAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYIDGDQGILLHRGYPIEQLAVD
SDYLDLCYLLLYGELPTKEQYAEFVHTVKTHTMVHEQLAFFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREI
AAYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFAVPCEEYKVNPIVERAMDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIARAKDKNDPFRLMGFGHRVYKNFDPRAKVMR
ETCHEVLKELKVQDPLLDVAMELERIALEDEYFISKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEML
DQPGHKISRPRQLYTGETSRDFVSQDKR
>Mature_427_residues
ADLKAKLELPGNDSIELPVKQGSAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYIDGDQGILLHRGYPIEQLAVDS
DYLDLCYLLLYGELPTKEQYAEFVHTVKTHTMVHEQLAFFFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREIA
AYRLVSKMPTIAAMCYKYSSGQPFVYPRNDLSYAGNFLSMMFAVPCEEYKVNPIVERAMDRIFILHADHEQNASTSTVRL
AGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIARAKDKNDPFRLMGFGHRVYKNFDPRAKVMRE
TCHEVLKELKVQDPLLDVAMELERIALEDEYFISKKLYPNVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLD
QPGHKISRPRQLYTGETSRDFVSQDKR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=366, Percent_Identity=27.0491803278689, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1786939, Length=428, Percent_Identity=76.8691588785047, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1786527, Length=373, Percent_Identity=31.9034852546917, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=367, Percent_Identity=26.9754768392371, Blast_Score=105, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319850, Length=374, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324328, Length=376, Percent_Identity=26.063829787234, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325257, Length=410, Percent_Identity=25.609756097561, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640126, Length=352, Percent_Identity=27.8409090909091, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24640124, Length=352, Percent_Identity=27.8409090909091, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356863, Length=362, Percent_Identity=25.6906077348066, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48068; Mature: 47936

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLKAKLELPGNDSIELPVKQGSAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYI
CCCCCEEEECCCCCCEEEEECCCCCCCCEEEHHHCCCCCEEEECCCCEEECCCCCCEEEE
DGDQGILLHRGYPIEQLAVDSDYLDLCYLLLYGELPTKEQYAEFVHTVKTHTMVHEQLAF
ECCCCEEEECCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREIAAYRLVSKMPTIAAMCYKYS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCC
SGQPFVYPRNDLSYAGNFLSMMFAVPCEEYKVNPIVERAMDRIFILHADHEQNASTSTVR
CCCCEEEECCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHEEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIARAKDKNDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEE
LMGFGHRVYKNFDPRAKVMRETCHEVLKELKVQDPLLDVAMELERIALEDEYFISKKLYP
EEECCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCC
NVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLDQPGHKISRPRQLYTGETSR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCH
DFVSQDKR
HHHHCCCC
>Mature Secondary Structure 
ADLKAKLELPGNDSIELPVKQGSAGFDVIDISKLGSKGYFTFDPGFLATASCESAITYI
CCCCEEEECCCCCCEEEEECCCCCCCCEEEHHHCCCCCEEEECCCCEEECCCCCCEEEE
DGDQGILLHRGYPIEQLAVDSDYLDLCYLLLYGELPTKEQYAEFVHTVKTHTMVHEQLAF
ECCCCEEEECCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFRGFRRDAHPMAMLCGVTGALSAFYQDSLDVNDPRHREIAAYRLVSKMPTIAAMCYKYS
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCC
SGQPFVYPRNDLSYAGNFLSMMFAVPCEEYKVNPIVERAMDRIFILHADHEQNASTSTVR
CCCCEEEECCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHEEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIASLWGPAHGGANEACLQMLEEIGSVDRIPEFIARAKDKNDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEE
LMGFGHRVYKNFDPRAKVMRETCHEVLKELKVQDPLLDVAMELERIALEDEYFISKKLYP
EEECCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCC
NVDFYSGIIMKAIGIPTSMFTVLFALARTVGWIAHWKEMLDQPGHKISRPRQLYTGETSR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCH
DFVSQDKR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]