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The map label for this gene is fur [H]

Identifier: 117920163

GI number: 117920163

Start: 2020295

End: 2020726

Strand: Reverse

Name: fur [H]

Synonym: Shewana3_1716

Alternate gene names: 117920163

Gene position: 2020726-2020295 (Counterclockwise)

Preceding gene: 117920168

Following gene: 117920152

Centisome position: 40.64

GC content: 43.75

Gene sequence:

>432_bases
ATGACAGATGGAAATCAAGCGCTCAAAAAAGCCGGTTTGAAAATCACCCTGCCACGAGTCAAGATCCTCGAACTGATGCA
AGGACCTGAAAACCAACATATCAGTGCAGAAGACTTATACAAGAAACTGCTCGATTTAGGTGAAGAAATTGGTCTAGCAA
CAGTTTACCGTGTATTAAACCAGTTTGATGATGCCGGTATCGTATCTCGCCACCACTTCGAAAGTGGCAAGGCGGTATTC
GAGTTATCGACTCAACACCACCACGATCACTTAGTGTGCCTCTCTTGCGGCAAAGTGATTGAGTTTTCAGACGAAGTGAT
TGAACGTCGTCAAGACGAGATCGCTAGCAAGTACAACATTAAACTGACTAACCACAGCTTATATTTGTACGGTCATTGCA
CTAACGATAAGTGCGATCATAACGACGAGTAA

Upstream 100 bases:

>100_bases
ATAAAGCTAGAACAAAGGTTTAAGTTTTTAATTTGACCCCCTATAATGGCATTCACTATCCACGGATGAACCTATTGGTT
CTGCAATCAAGAGATTAGCA

Downstream 100 bases:

>100_bases
GCAGATTTAGCTCAATCTGGATATCAACCAGACAGGCCTAATAAAAAAACCAGCCATCTAGGCTGGTTTTTTTATTGAAA
CGCTCAGGCACTGTTAGAGC

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MTDGNQALKKAGLKITLPRVKILELMQGPENQHISAEDLYKKLLDLGEEIGLATVYRVLNQFDDAGIVSRHHFESGKAVF
ELSTQHHHDHLVCLSCGKVIEFSDEVIERRQDEIASKYNIKLTNHSLYLYGHCTNDKCDHNDE

Sequences:

>Translated_143_residues
MTDGNQALKKAGLKITLPRVKILELMQGPENQHISAEDLYKKLLDLGEEIGLATVYRVLNQFDDAGIVSRHHFESGKAVF
ELSTQHHHDHLVCLSCGKVIEFSDEVIERRQDEIASKYNIKLTNHSLYLYGHCTNDKCDHNDE
>Mature_142_residues
TDGNQALKKAGLKITLPRVKILELMQGPENQHISAEDLYKKLLDLGEEIGLATVYRVLNQFDDAGIVSRHHFESGKAVFE
LSTQHHHDHLVCLSCGKVIEFSDEVIERRQDEIASKYNIKLTNHSLYLYGHCTNDKCDHNDE

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=76.0869565217391, Blast_Score=229, Evalue=7e-62,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16287; Mature: 16155

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGNQALKKAGLKITLPRVKILELMQGPENQHISAEDLYKKLLDLGEEIGLATVYRVLN
CCCHHHHHHHCCCEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEFSDEVIERRQDEIASKYNI
HCCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCEECCHHHHHHHHHHHHHHEEE
KLTNHSLYLYGHCTNDKCDHNDE
EEECCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TDGNQALKKAGLKITLPRVKILELMQGPENQHISAEDLYKKLLDLGEEIGLATVYRVLN
CCHHHHHHHCCCEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVSRHHFESGKAVFELSTQHHHDHLVCLSCGKVIEFSDEVIERRQDEIASKYNI
HCCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCEECCHHHHHHHHHHHHHHEEE
KLTNHSLYLYGHCTNDKCDHNDE
EEECCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1372314 [H]