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The map label for this gene is mdtA [H]

Identifier: 117920151

GI number: 117920151

Start: 2006161

End: 2007225

Strand: Reverse

Name: mdtA [H]

Synonym: Shewana3_1704

Alternate gene names: 117920151

Gene position: 2007225-2006161 (Counterclockwise)

Preceding gene: 117920152

Following gene: 117920150

Centisome position: 40.37

GC content: 49.67

Gene sequence:

>1065_bases
ATGGAAAAGTCAACAATTGCTAAGTTCGCCCTACCCGTGCTGTTAGTGTCAATGTTAGCAGCATGCGGCGAAGAGGAAGT
GGCTAAAAAAGAAGAACAATATGCCATTCCCGTCGAAACCACTACCGTGATGCAGGGTAATGTGTCTTCGTTTTATAGCA
CTACCGCCACCCTCGAAGCCCCACAGGAAGCTAACGTCGTGAGCCGCATCGCAGGCCTTATCGAAGCCATTAATGTCGAA
GAAGGCGACCGGGTGCAAAAAGGACAAATCCTCGCGGTTATCGATGCCAAACGCCAGCAATACGATCTCGACCGCTCCGA
AGCCGAAGTGAAAATCATCGAGCAAGAGTTAAACCGCTTGAAGAAGATGACCAATAAAGAGTTTATCAGTGCCGACTCCA
TGGCAAAGCTCGAATACAACCTGCAAGCCGCCATTGCAAGACGGGATCTTGCTGAATTACAAGTTAAAGAAAGCCATGTG
GTTTCGCCCATCGATGGTATTGTTGCTAAACGTTATGTCAAAGCGGGCAACATGGCGCAGGAATTTGGTGACCTCTTCTA
TATCGTCAATCAAGACGAGCTGCACGGGATTGTCCATTTACCCGAGCAACAATTAACTAGCCTACGTTTAGGCCAAGAAG
CCCAAGTCTTTAGCAATCAACAGAGCAAAAATGCCATCCACGCGAAAGTGCTGCGCATCAGCCCTGTGGTCGACCCACAG
AGCGGCACCTTTAAAGTCACCTTGGCCGTGCCCAATCAAAATGCGCATTTAAAAGCCGGGATGTTCACACGGGTCGAATT
GAAGTATGACACCCATGAGAATGTGATCACTGTGCCCTACAGTGCCCTGATCAACCAAGACAATAAGCAAGCCCTGTATG
TGATTGACGGCAGCAATGCCAACCGCCGCGAAGTCGAAATCGGCTACCGCGAAGGTGACTCGGTGGAAGTCGTCTCCGGT
ATCAAACCCGGCGAGCAAGTCGTGACCCGTGGTCAGCAAAATTTGAAAGACCAATCCTTAGTTGAAGTCATTACCCCACT
CGATTTGGCCTCAGCGAAGAACTGA

Upstream 100 bases:

>100_bases
GACAAATTTAAGTTAATCTACTGAAATTAATGCATTTTTAACTTTGGCATGTTTTCTGCTTTCAGATGGCATCACAAAAA
TGACAACAGGTAATACTCTT

Downstream 100 bases:

>100_bases
TAGGAGTCTTTCATGTCAATCATCAGCACCTCAGTTAAACGGCCAGTCACGGTATGGATGTTCATGCTGGCCATTATGTT
ATTCGGTATGGTGGGGTTTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEKSTIAKFALPVLLVSMLAACGEEEVAKKEEQYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRIAGLIEAINVE
EGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMTNKEFISADSMAKLEYNLQAAIARRDLAELQVKESHV
VSPIDGIVAKRYVKAGNMAQEFGDLFYIVNQDELHGIVHLPEQQLTSLRLGQEAQVFSNQQSKNAIHAKVLRISPVVDPQ
SGTFKVTLAVPNQNAHLKAGMFTRVELKYDTHENVITVPYSALINQDNKQALYVIDGSNANRREVEIGYREGDSVEVVSG
IKPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN

Sequences:

>Translated_354_residues
MEKSTIAKFALPVLLVSMLAACGEEEVAKKEEQYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRIAGLIEAINVE
EGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMTNKEFISADSMAKLEYNLQAAIARRDLAELQVKESHV
VSPIDGIVAKRYVKAGNMAQEFGDLFYIVNQDELHGIVHLPEQQLTSLRLGQEAQVFSNQQSKNAIHAKVLRISPVVDPQ
SGTFKVTLAVPNQNAHLKAGMFTRVELKYDTHENVITVPYSALINQDNKQALYVIDGSNANRREVEIGYREGDSVEVVSG
IKPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
>Mature_354_residues
MEKSTIAKFALPVLLVSMLAACGEEEVAKKEEQYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRIAGLIEAINVE
EGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMTNKEFISADSMAKLEYNLQAAIARRDLAELQVKESHV
VSPIDGIVAKRYVKAGNMAQEFGDLFYIVNQDELHGIVHLPEQQLTSLRLGQEAQVFSNQQSKNAIHAKVLRISPVVDPQ
SGTFKVTLAVPNQNAHLKAGMFTRVELKYDTHENVITVPYSALINQDNKQALYVIDGSNANRREVEIGYREGDSVEVVSG
IKPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=332, Percent_Identity=25.3012048192771, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081796, Length=330, Percent_Identity=23.6363636363636, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789929, Length=362, Percent_Identity=23.7569060773481, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789637, Length=187, Percent_Identity=28.8770053475936, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789665, Length=390, Percent_Identity=23.8461538461538, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1786668, Length=372, Percent_Identity=22.8494623655914, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39146; Mature: 39146

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSTIAKFALPVLLVSMLAACGEEEVAKKEEQYAIPVETTTVMQGNVSSFYSTTATLEA
CCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHCEECCCEEEEEEECCHHHHHCCEEEECC
PQEANVVSRIAGLIEAINVEEGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHH
KKMTNKEFISADSMAKLEYNLQAAIARRDLAELQVKESHVVSPIDGIVAKRYVKAGNMAQ
HHHCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHH
EFGDLFYIVNQDELHGIVHLPEQQLTSLRLGQEAQVFSNQQSKNAIHAKVLRISPVVDPQ
HCCCEEEEECCCCCCCEEECCHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEEEECCCCCC
SGTFKVTLAVPNQNAHLKAGMFTRVELKYDTHENVITVPYSALINQDNKQALYVIDGSNA
CCEEEEEEEECCCCCEEEECEEEEEEEEECCCCCEEEECHHHHHCCCCCEEEEEEECCCC
NRREVEIGYREGDSVEVVSGIKPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
CCEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MEKSTIAKFALPVLLVSMLAACGEEEVAKKEEQYAIPVETTTVMQGNVSSFYSTTATLEA
CCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHCEECCCEEEEEEECCHHHHHCCEEEECC
PQEANVVSRIAGLIEAINVEEGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHH
KKMTNKEFISADSMAKLEYNLQAAIARRDLAELQVKESHVVSPIDGIVAKRYVKAGNMAQ
HHHCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHH
EFGDLFYIVNQDELHGIVHLPEQQLTSLRLGQEAQVFSNQQSKNAIHAKVLRISPVVDPQ
HCCCEEEEECCCCCCCEEECCHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEEEECCCCCC
SGTFKVTLAVPNQNAHLKAGMFTRVELKYDTHENVITVPYSALINQDNKQALYVIDGSNA
CCEEEEEEEECCCCCEEEECEEEEEEEEECCCCCEEEECHHHHHCCCCCEEEEEEECCCC
NRREVEIGYREGDSVEVVSGIKPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
CCEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]