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The map label for this gene is yeeO [C]

Identifier: 117920146

GI number: 117920146

Start: 1997135

End: 1998697

Strand: Direct

Name: yeeO [C]

Synonym: Shewana3_1699

Alternate gene names: 117920146

Gene position: 1997135-1998697 (Clockwise)

Preceding gene: 117920145

Following gene: 117920148

Centisome position: 40.17

GC content: 52.02

Gene sequence:

>1563_bases
ATGACCCAAGCCAAATTCGTTGAAGGTTCGATTCTTCGTCATATCCTCGTGATGAGTTCGACCGCCGCCGTGGGGATTTC
TGCCTTATTTGTAGTCGATTTGCTCGATATTTTCTTCTTAAGTTTGCTTGGTGAACATGAACTGGCCGCGGCGGTGGGCT
ATGCGGGCAGCATTTCGTTTTTTACCACTTCGATTGGTATTGGTCTCTCGATTGCACTCGGCGCGTTAGTTTCCCGCTCG
ATTGGCGCAAAGGATGTGGAACTGGCCAAACGCCTATTGCTCAATAGTGCGGCGGTGACCACCTTAATCAGCCTCTTTGT
GAGTGTGGTGGTGACCTGTTTTATTCCCGAATTAGTGACCTTGGTGGGGGCGAGCGGCCATACCGCCGAACTTGCCGAGA
GTTATCTGTACATTTTGGTGCCTTCTTTACCCTTTATTTGCCTTGCGATGGCCCTTGGCGGTGCGCTGCGTGCCGTTGGG
GATGCCAAGCTGTCGATGATGTCGACCTTAGCGGGCGGCGGGGTTAATGCGGTACTGGATCCGATTTTTATTTTTCTGTT
TGCCATGGGGATTGAAGGCGCGGCACTGGCGTCGGTGCTTGCCCGTATCGCGGTCTTTATCATTGCCGGGCGCGGCGTAG
TCGTAAAACATCAGCTGCTGGGTAAGTTTAACTTCAGCTATTTTGTTGCCGATCTCAAACCGATTTTCGCCATTGCCGGG
CCCGCCATGCTGACGAATATCGCTACGCCCATAGGTAACGCCTTTGTGACCCGCGCGATTGCCGATTTTGGTGATGCCTA
TGTTGCCGGTTGGGCGGTGCTTGGTAGATTAATCCCAGTCACCTTTGGGATGATTTTTGCGTTATCCGGTGCCATTGGGC
CGATTGTTGGGCAAAACTTTGGCGCGGGCCGATTCGACCGGGTGCGTGAGAGTTTAACCAAGGCGATTCAATTTTGTACC
TTGTATGTGGTGGTGATGTCGCTATTGCTGTTCTTGCTCAAATCGCAGGTGGTGAGCCTGTTCGATATGAAAGGCGATAG
CGCGGCGCTTATTGAGTTTTTCTGTAGCTATATCGCGGTGTTTTTTACCTTCTCTGGCATTTTATTTGTGGCCAATGCTT
CGTTTAATAATCTGGGTAAAGCCAAATATTCCACCCTGTTCAACGTGGGTAAAGCGACGTTAGGCACTGTGCCATTCGTG
TATTTGGGCGCGCAGTGGGGCGGGGTATACGGTGTGTTAATCGGCCAAGTATTAGGCTCCATTCTTTTTGGGGTCATGGG
TGTATGGGTGGCCTACCGCTTAGTCGATAAAGTCGCAGTCGCAAGTCGTGCAAGCGCAGCGCAGCCTGTCGTGAGCGATA
CCGAAGAGGCGCAGAATAAGTGCCAGCAGCTACTGGCGGGGGATGAGGAAGAAATTGCCAATTGTGTTGGCCAAAATCTG
CCCTCATCTACGAGTCCGTTTTCATCCTCCCATGTGCAAATGGGCCAATTGACCGAAGAGCAGGAATGCGAGGCGGCCAC
GGCCGCGGTGGATTTTGATAAAGCGAAACCGAATACGCCGTAA

Upstream 100 bases:

>100_bases
CTCATGGTAGGCTTACTTACTCAAGAGACTGCTAAAGTGGCGAGAGCCACAGACTGGATTTGATGTCAGTCCATCCAATA
GATCAAGGTAAAACAACCCC

Downstream 100 bases:

>100_bases
ACCCTGAGATAACCATCTTGGTAATTTAAAGAGTCATAAAAATTCATAAAGCATAAAGGCCACTGAAAAGTGGCCTTTAT
GTTTGGTATGTTCGCATTCA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTQAKFVEGSILRHILVMSSTAAVGISALFVVDLLDIFFLSLLGEHELAAAVGYAGSISFFTTSIGIGLSIALGALVSRS
IGAKDVELAKRLLLNSAAVTTLISLFVSVVVTCFIPELVTLVGASGHTAELAESYLYILVPSLPFICLAMALGGALRAVG
DAKLSMMSTLAGGGVNAVLDPIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGKFNFSYFVADLKPIFAIAG
PAMLTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLIPVTFGMIFALSGAIGPIVGQNFGAGRFDRVRESLTKAIQFCT
LYVVVMSLLLFLLKSQVVSLFDMKGDSAALIEFFCSYIAVFFTFSGILFVANASFNNLGKAKYSTLFNVGKATLGTVPFV
YLGAQWGGVYGVLIGQVLGSILFGVMGVWVAYRLVDKVAVASRASAAQPVVSDTEEAQNKCQQLLAGDEEEIANCVGQNL
PSSTSPFSSSHVQMGQLTEEQECEAATAAVDFDKAKPNTP

Sequences:

>Translated_520_residues
MTQAKFVEGSILRHILVMSSTAAVGISALFVVDLLDIFFLSLLGEHELAAAVGYAGSISFFTTSIGIGLSIALGALVSRS
IGAKDVELAKRLLLNSAAVTTLISLFVSVVVTCFIPELVTLVGASGHTAELAESYLYILVPSLPFICLAMALGGALRAVG
DAKLSMMSTLAGGGVNAVLDPIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGKFNFSYFVADLKPIFAIAG
PAMLTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLIPVTFGMIFALSGAIGPIVGQNFGAGRFDRVRESLTKAIQFCT
LYVVVMSLLLFLLKSQVVSLFDMKGDSAALIEFFCSYIAVFFTFSGILFVANASFNNLGKAKYSTLFNVGKATLGTVPFV
YLGAQWGGVYGVLIGQVLGSILFGVMGVWVAYRLVDKVAVASRASAAQPVVSDTEEAQNKCQQLLAGDEEEIANCVGQNL
PSSTSPFSSSHVQMGQLTEEQECEAATAAVDFDKAKPNTP
>Mature_519_residues
TQAKFVEGSILRHILVMSSTAAVGISALFVVDLLDIFFLSLLGEHELAAAVGYAGSISFFTTSIGIGLSIALGALVSRSI
GAKDVELAKRLLLNSAAVTTLISLFVSVVVTCFIPELVTLVGASGHTAELAESYLYILVPSLPFICLAMALGGALRAVGD
AKLSMMSTLAGGGVNAVLDPIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGKFNFSYFVADLKPIFAIAGP
AMLTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLIPVTFGMIFALSGAIGPIVGQNFGAGRFDRVRESLTKAIQFCTL
YVVVMSLLLFLLKSQVVSLFDMKGDSAALIEFFCSYIAVFFTFSGILFVANASFNNLGKAKYSTLFNVGKATLGTVPFVY
LGAQWGGVYGVLIGQVLGSILFGVMGVWVAYRLVDKVAVASRASAAQPVVSDTEEAQNKCQQLLAGDEEEIANCVGQNLP
SSTSPFSSSHVQMGQLTEEQECEAATAAVDFDKAKPNTP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI22907060, Length=429, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI153792564, Length=361, Percent_Identity=22.1606648199446, Blast_Score=66, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 54583; Mature: 54451

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAKFVEGSILRHILVMSSTAAVGISALFVVDLLDIFFLSLLGEHELAAAVGYAGSISF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHH
FTTSIGIGLSIALGALVSRSIGAKDVELAKRLLLNSAAVTTLISLFVSVVVTCFIPELVT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGASGHTAELAESYLYILVPSLPFICLAMALGGALRAVGDAKLSMMSTLAGGGVNAVLD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGKFNFSYFVADLKPIFAIAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHH
PAMLTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLIPVTFGMIFALSGAIGPIVGQNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAGRFDRVRESLTKAIQFCTLYVVVMSLLLFLLKSQVVSLFDMKGDSAALIEFFCSYIAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FFTFSGILFVANASFNNLGKAKYSTLFNVGKATLGTVPFVYLGAQWGGVYGVLIGQVLGS
HHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHEECCCHHHHHHHHHHHHHHH
ILFGVMGVWVAYRLVDKVAVASRASAAQPVVSDTEEAQNKCQQLLAGDEEEIANCVGQNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCC
PSSTSPFSSSHVQMGQLTEEQECEAATAAVDFDKAKPNTP
CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQAKFVEGSILRHILVMSSTAAVGISALFVVDLLDIFFLSLLGEHELAAAVGYAGSISF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHH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CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]