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The map label for this gene is yngE [H]

Identifier: 117920118

GI number: 117920118

Start: 1962950

End: 1964557

Strand: Reverse

Name: yngE [H]

Synonym: Shewana3_1671

Alternate gene names: 117920118

Gene position: 1964557-1962950 (Counterclockwise)

Preceding gene: 117920119

Following gene: 117920117

Centisome position: 39.51

GC content: 54.23

Gene sequence:

>1608_bases
GTGACGCAATTAAGCAGTCGTATCAACGCCCGTAGCGATGAATTTAAAGCCAAATCCGATGATATGGCCGCCCTAGTGGC
CGATCTTAAAACCAAACTCGCCAAAATTGAACTTGGCGGCGGCCCCGTTGCCCTAGAGCGCCATTTGGCCCGCGGCAAAC
TCCTTCCCCGTCAACGGGTTGAGAAACTCCTCGACGCTGGTTCGCCCTTTTTAGAACTGTCCCAGTTCGCCGCCTTCGAC
GTTTACGATGAAGAAGTACCCGCCGCAGGAATTATCGCCGGTATCGGCCGAGTGAGCGGCGTAGAGTGCATGATTATCGC
CAACGATGCCACGGTCAAAGGCGGCACTTACTACCCTATCACGGTCAAAAAACACTTAAGGGCACAAGAGATTGCCAGCC
GCTGTCATCTGCCCTGCATCTATTTAGTCGACTCTGGCGGCGCTAACTTGCCCCGTCAGGATGAAGTCTTCCCGGATCGC
GACCATTTCGGCCGGATTTTCTACAACCAAGCACAAATGTCCGCCAAGGGCATTCCGCAAATTGCGGTGGTGATGGGTCT
GTGTACCGCGGGCGGCGCCTATGTGCCTGCCATGGCCGATGAATCTATTATAGTTAAAGAACAAGGCACTATCTTTTTAG
CTGGGCCGCCGTTAGTTAAAGCCGCGACCGGTGAGGAAGTCAGCGCCGAAGAACTCGGCGGCGCCGACGTACACACTAAA
ATTTCGGGTGTAGCGGACCACTTAGCCCAAAACGATGAGCATGCCTTAGAGCTTGCCCGCCGCGCTGTGCTGCGTCTGAA
TCATCAAAAACAAATCAATAGTCTGCTGAGCCCAGTTAAGCCACCTAAGTTTGATATCAGCGAACTCTATGGCATTGTCG
GCACCGACTTGAAAAAGCCCTTCGATGTGAAAGAAGTGATCGCCCGCATCGTCGACGACTCCGATTTCGATGAGTTTAAG
GCCAACTATGGCGCTACTTTAGTCTGTGGTTTTGCCCGTATTCACGGTTATCCCGTAGGGATTGTGGCCAACAATGGCAT
TTTATTCTCCGAATCAGCGCAAAAAGGCGCGCACTTTATCGAACTGTGCTGCCAGCGCAAGATACCGCTGCTGTTCCTGC
AAAACATCACCGGCTTTATGGTGGGTAAAAAGTACGAACACGAAGGTATCGCTAAGCACGGCGCCAAGATGGTGACCGCA
GTCTCCTGCGCCAATGTGCCTAAATTCACTGTGATTATCGGTGGCAGCTACGGCGCGGGTAACTACGGTATGTGTGGCCG
CGCCTTCGAACCAACCATGATGTGGATGTGGCCCAATGCGCGCATCTCTGTGATGGGTGGCGAGCAAGCCGCAGGCGTAT
TAGCCACAGTGCGCCGCGACGGCTTAGCCCGTAAAGGCGAAGAATGGTCTGCTGAGGATGAAAAGGCCTTCAAGGCGCCG
ATTATTGCCCAGTACGATAAAGAGGGTCATCCCTACCATGCCAGCGCCCGCCTGTGGGATGACGGCATTATCGACCCGGC
GCAAACCCGTGATGTGGTGGGCCTTGCCCTGTCAGCCGCATTAAATGCCCCTATCGAAGACACCCGCTTCGGCGTCTTCC
GTATGTAA

Upstream 100 bases:

>100_bases
GCAGCCTAGGGCGAACGGCGCATGACGAGCTTTAGCCTTTCATGCTCCTCGCCCACCGAGCCAACTGATACTGAGTTACC
GCTTTATAAGGACAATCAAA

Downstream 100 bases:

>100_bases
CGCATCTTGCGATGCCTTACGTATCACTCATAGAGGGAATCACTATGACGGGAATAATAATGACTGACACACAACACCAG
AACACTAGCACTCAATCCTT

Product: carboxyl transferase

Products: ADP; phosphate; 3-methylglutaconyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTQLSSRINARSDEFKAKSDDMAALVADLKTKLAKIELGGGPVALERHLARGKLLPRQRVEKLLDAGSPFLELSQFAAFD
VYDEEVPAAGIIAGIGRVSGVECMIIANDATVKGGTYYPITVKKHLRAQEIASRCHLPCIYLVDSGGANLPRQDEVFPDR
DHFGRIFYNQAQMSAKGIPQIAVVMGLCTAGGAYVPAMADESIIVKEQGTIFLAGPPLVKAATGEEVSAEELGGADVHTK
ISGVADHLAQNDEHALELARRAVLRLNHQKQINSLLSPVKPPKFDISELYGIVGTDLKKPFDVKEVIARIVDDSDFDEFK
ANYGATLVCGFARIHGYPVGIVANNGILFSESAQKGAHFIELCCQRKIPLLFLQNITGFMVGKKYEHEGIAKHGAKMVTA
VSCANVPKFTVIIGGSYGAGNYGMCGRAFEPTMMWMWPNARISVMGGEQAAGVLATVRRDGLARKGEEWSAEDEKAFKAP
IIAQYDKEGHPYHASARLWDDGIIDPAQTRDVVGLALSAALNAPIEDTRFGVFRM

Sequences:

>Translated_535_residues
MTQLSSRINARSDEFKAKSDDMAALVADLKTKLAKIELGGGPVALERHLARGKLLPRQRVEKLLDAGSPFLELSQFAAFD
VYDEEVPAAGIIAGIGRVSGVECMIIANDATVKGGTYYPITVKKHLRAQEIASRCHLPCIYLVDSGGANLPRQDEVFPDR
DHFGRIFYNQAQMSAKGIPQIAVVMGLCTAGGAYVPAMADESIIVKEQGTIFLAGPPLVKAATGEEVSAEELGGADVHTK
ISGVADHLAQNDEHALELARRAVLRLNHQKQINSLLSPVKPPKFDISELYGIVGTDLKKPFDVKEVIARIVDDSDFDEFK
ANYGATLVCGFARIHGYPVGIVANNGILFSESAQKGAHFIELCCQRKIPLLFLQNITGFMVGKKYEHEGIAKHGAKMVTA
VSCANVPKFTVIIGGSYGAGNYGMCGRAFEPTMMWMWPNARISVMGGEQAAGVLATVRRDGLARKGEEWSAEDEKAFKAP
IIAQYDKEGHPYHASARLWDDGIIDPAQTRDVVGLALSAALNAPIEDTRFGVFRM
>Mature_534_residues
TQLSSRINARSDEFKAKSDDMAALVADLKTKLAKIELGGGPVALERHLARGKLLPRQRVEKLLDAGSPFLELSQFAAFDV
YDEEVPAAGIIAGIGRVSGVECMIIANDATVKGGTYYPITVKKHLRAQEIASRCHLPCIYLVDSGGANLPRQDEVFPDRD
HFGRIFYNQAQMSAKGIPQIAVVMGLCTAGGAYVPAMADESIIVKEQGTIFLAGPPLVKAATGEEVSAEELGGADVHTKI
SGVADHLAQNDEHALELARRAVLRLNHQKQINSLLSPVKPPKFDISELYGIVGTDLKKPFDVKEVIARIVDDSDFDEFKA
NYGATLVCGFARIHGYPVGIVANNGILFSESAQKGAHFIELCCQRKIPLLFLQNITGFMVGKKYEHEGIAKHGAKMVTAV
SCANVPKFTVIIGGSYGAGNYGMCGRAFEPTMMWMWPNARISVMGGEQAAGVLATVRRDGLARKGEEWSAEDEKAFKAPI
IAQYDKEGHPYHASARLWDDGIIDPAQTRDVVGLALSAALNAPIEDTRFGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=536, Percent_Identity=68.8432835820896, Blast_Score=751, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=489, Percent_Identity=33.3333333333333, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI295821216, Length=509, Percent_Identity=32.2200392927308, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI310133460, Length=132, Percent_Identity=64.3939393939394, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552936, Length=533, Percent_Identity=63.2270168855535, Blast_Score=710, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=493, Percent_Identity=32.8600405679513, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI25147359, Length=493, Percent_Identity=32.8600405679513, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24586065, Length=549, Percent_Identity=66.120218579235, Blast_Score=749, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: 6.4.1.4

Molecular weight: Translated: 57896; Mature: 57765

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLSSRINARSDEFKAKSDDMAALVADLKTKLAKIELGGGPVALERHLARGKLLPRQRV
CCCCHHHHCCCCHHCCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCCHHHH
EKLLDAGSPFLELSQFAAFDVYDEEVPAAGIIAGIGRVSGVECMIIANDATVKGGTYYPI
HHHHHCCCCHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCEEEEEEECCCEECCCEEEEE
TVKKHLRAQEIASRCHLPCIYLVDSGGANLPRQDEVFPDRDHFGRIFYNQAQMSAKGIPQ
EHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCEEEEHHHHCCCCCCH
IAVVMGLCTAGGAYVPAMADESIIVKEQGTIFLAGPPLVKAATGEEVSAEELGGADVHTK
HHHHHHHHHCCCCEEECCCCCEEEEEECCEEEEECCCEEEECCCCCCCHHHCCCCCHHHH
ISGVADHLAQNDEHALELARRAVLRLNHQKQINSLLSPVKPPKFDISELYGIVGTDLKKP
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
FDVKEVIARIVDDSDFDEFKANYGATLVCGFARIHGYPVGIVANNGILFSESAQKGAHFI
CCHHHHHHHHHCCCCHHHHHHCCCCEEEEEHHHHCCEEEEEEECCCEEEECCHHHHHHHH
ELCCQRKIPLLFLQNITGFMVGKKYEHEGIAKHGAKMVTAVSCANVPKFTVIIGGSYGAG
HHHHHCCCCEEEHHCCHHHHCCCCCCCCCHHHHCCHHEEEEHHCCCCEEEEEEECCCCCC
NYGMCGRAFEPTMMWMWPNARISVMGGEQAAGVLATVRRDGLARKGEEWSAEDEKAFKAP
CCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
IIAQYDKEGHPYHASARLWDDGIIDPAQTRDVVGLALSAALNAPIEDTRFGVFRM
EEEEECCCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECC
>Mature Secondary Structure 
TQLSSRINARSDEFKAKSDDMAALVADLKTKLAKIELGGGPVALERHLARGKLLPRQRV
CCCHHHHCCCCHHCCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCCHHHH
EKLLDAGSPFLELSQFAAFDVYDEEVPAAGIIAGIGRVSGVECMIIANDATVKGGTYYPI
HHHHHCCCCHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCEEEEEEECCCEECCCEEEEE
TVKKHLRAQEIASRCHLPCIYLVDSGGANLPRQDEVFPDRDHFGRIFYNQAQMSAKGIPQ
EHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCEEEEHHHHCCCCCCH
IAVVMGLCTAGGAYVPAMADESIIVKEQGTIFLAGPPLVKAATGEEVSAEELGGADVHTK
HHHHHHHHHCCCCEEECCCCCEEEEEECCEEEEECCCEEEECCCCCCCHHHCCCCCHHHH
ISGVADHLAQNDEHALELARRAVLRLNHQKQINSLLSPVKPPKFDISELYGIVGTDLKKP
HHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
FDVKEVIARIVDDSDFDEFKANYGATLVCGFARIHGYPVGIVANNGILFSESAQKGAHFI
CCHHHHHHHHHCCCCHHHHHHCCCCEEEEEHHHHCCEEEEEEECCCEEEECCHHHHHHHH
ELCCQRKIPLLFLQNITGFMVGKKYEHEGIAKHGAKMVTAVSCANVPKFTVIIGGSYGAG
HHHHHCCCCEEEHHCCHHHHCCCCCCCCCHHHHCCHHEEEEHHCCCCEEEEEEECCCCCC
NYGMCGRAFEPTMMWMWPNARISVMGGEQAAGVLATVRRDGLARKGEEWSAEDEKAFKAP
CCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
IIAQYDKEGHPYHASARLWDDGIIDPAQTRDVVGLALSAALNAPIEDTRFGVFRM
EEEEECCCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-methylcrotonoyl-CoA; HCO3-

Specific reaction: ATP + 3-methylcrotonoyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]