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The map label for this gene is siaT [H]

Identifier: 117919862

GI number: 117919862

Start: 1638728

End: 1640125

Strand: Reverse

Name: siaT [H]

Synonym: Shewana3_1414

Alternate gene names: 117919862

Gene position: 1640125-1638728 (Counterclockwise)

Preceding gene: 117919863

Following gene: 117919861

Centisome position: 32.99

GC content: 51.0

Gene sequence:

>1398_bases
ATGGCCATTGCGACCCTCTTTACTGCCCTACTCGTCTGTATGTTTTTAGGTATGCCTATCGCGATTGCGTTAGGTTTCTC
GAGCATGCTGACGATTTTATTCTTCTCCAACGACTCCCTCGCCTCAGTGGCGTTAAAACTTTATGAGTCATCGTCAGAGC
ACTATACCCTGCTGGCGATCCCCTTCTTTATTCTGTCCTCAGCCTTTCTGTCAACCGGTGGGGTGGCACGACGGATCATC
GACTTTGCGATGGACAGTATCGGCCATATCCGTGGCGGTTTAGCCATGGCCTCTGTGATGGCCTGTATGTTGTTTGCCGC
GGTATCGGGTTCATCTCCAGCAACTGTGGCCGCCATCGGTTCCATTGTTATCGTCGGTATGGTGAAAGCAGGTTACCCCG
AAAAGTTTGCCGCCGGTGTGATTACCACTTCTGGCACCTTAGGGATTTTGATCCCCCCTTCAATCGTGATGCTAGTGTAT
GCGGCGGCGACGGAAGTCTCGGCTGCCAGAATGTTTATGGCGGGCTTAATCCCAGGTTTGATGATGGGTTTCCTGCTGAT
GATAGTGATTTATATCGTCGCCCGTTTTAAAAATCTGCCATCACGCCCCTTCCCTGGCTTTAAACAACTGGGGATTTCCA
GTGCTAAAGCCTTAGGTGGTCTGGCGCTGATCATTATCGTGTTAGGTTCAATCTATGGCGGTGTAGCCAGTCCAACCGAA
GCCTCTGCCGTAGCCTGTATGTATGCCTATTTCATTGCGGTATTTGGTTATCGCGATATTGGCCCATTGAAAAATGTCGC
ATGGCGTAACCCTAATGAGCCGATCCCCAGCGCCATTGTCCGTAACTTAGGCCATATGGCGCTCGGACTGATTAAAACCC
CAATCGACAAAGAAATCCGCCATGTGGTGCGCGACGGGGCAAAGGTCAGCATCATGTTGCTGTTTATCATTGCCAACGCC
ATGCTATTCGCCCACGTGCTGACTACTGAGCGTATTCCCCATATCATTGCCGAACATATTGTGGGCATGGGCTTACCTGC
GTGGGGCTTCTTAATCATTGTCAACTTACTGCTGTTAGCGGCGGGTAACTTTATGGAGCCATCGGCCATCGTGCTGATTA
TGGCGCCAATCTTGTTCCCGATTGCCACCCACTTAGGTATCGACCCTATCCACTTAGGCATCATCATGGTGGTGAACATG
GAGATTGGTATGCTGACACCGCCGGTGGGGCTTAACCTCTTCGTGACGGCGGGGATCACAGGCCGCAGTATCGGCTGGGT
GATCCAATCAGTACTACCTTGGTTAGCACTGATGTTGGCCTTCTTGGCGCTTATCACCTACGTGCCACAAATCTCCCTGT
TCTTGCCAGAATTTCTGGATAAGCTCAACGGATATTAA

Upstream 100 bases:

>100_bases
CTGGATTCCAATTTGCCGATGAAGCGAAAGAAAGCATGCATTTAATTGACGAAGCTGCTCAGCACGCACAACAAGAAACA
GACAATAAGGAAGCGAAGTA

Downstream 100 bases:

>100_bases
TCTCAAGGAATAAGGATTATTCCTTGATTCTAGATAGTTTTTAAGCGAGCCTACTCAGGCTCGCTTTGTTTTATTCAGTG
TGGACAGGATTACCTGCTAT

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MAIATLFTALLVCMFLGMPIAIALGFSSMLTILFFSNDSLASVALKLYESSSEHYTLLAIPFFILSSAFLSTGGVARRII
DFAMDSIGHIRGGLAMASVMACMLFAAVSGSSPATVAAIGSIVIVGMVKAGYPEKFAAGVITTSGTLGILIPPSIVMLVY
AAATEVSAARMFMAGLIPGLMMGFLLMIVIYIVARFKNLPSRPFPGFKQLGISSAKALGGLALIIIVLGSIYGGVASPTE
ASAVACMYAYFIAVFGYRDIGPLKNVAWRNPNEPIPSAIVRNLGHMALGLIKTPIDKEIRHVVRDGAKVSIMLLFIIANA
MLFAHVLTTERIPHIIAEHIVGMGLPAWGFLIIVNLLLLAAGNFMEPSAIVLIMAPILFPIATHLGIDPIHLGIIMVVNM
EIGMLTPPVGLNLFVTAGITGRSIGWVIQSVLPWLALMLAFLALITYVPQISLFLPEFLDKLNGY

Sequences:

>Translated_465_residues
MAIATLFTALLVCMFLGMPIAIALGFSSMLTILFFSNDSLASVALKLYESSSEHYTLLAIPFFILSSAFLSTGGVARRII
DFAMDSIGHIRGGLAMASVMACMLFAAVSGSSPATVAAIGSIVIVGMVKAGYPEKFAAGVITTSGTLGILIPPSIVMLVY
AAATEVSAARMFMAGLIPGLMMGFLLMIVIYIVARFKNLPSRPFPGFKQLGISSAKALGGLALIIIVLGSIYGGVASPTE
ASAVACMYAYFIAVFGYRDIGPLKNVAWRNPNEPIPSAIVRNLGHMALGLIKTPIDKEIRHVVRDGAKVSIMLLFIIANA
MLFAHVLTTERIPHIIAEHIVGMGLPAWGFLIIVNLLLLAAGNFMEPSAIVLIMAPILFPIATHLGIDPIHLGIIMVVNM
EIGMLTPPVGLNLFVTAGITGRSIGWVIQSVLPWLALMLAFLALITYVPQISLFLPEFLDKLNGY
>Mature_464_residues
AIATLFTALLVCMFLGMPIAIALGFSSMLTILFFSNDSLASVALKLYESSSEHYTLLAIPFFILSSAFLSTGGVARRIID
FAMDSIGHIRGGLAMASVMACMLFAAVSGSSPATVAAIGSIVIVGMVKAGYPEKFAAGVITTSGTLGILIPPSIVMLVYA
AATEVSAARMFMAGLIPGLMMGFLLMIVIYIVARFKNLPSRPFPGFKQLGISSAKALGGLALIIIVLGSIYGGVASPTEA
SAVACMYAYFIAVFGYRDIGPLKNVAWRNPNEPIPSAIVRNLGHMALGLIKTPIDKEIRHVVRDGAKVSIMLLFIIANAM
LFAHVLTTERIPHIIAEHIVGMGLPAWGFLIIVNLLLLAAGNFMEPSAIVLIMAPILFPIATHLGIDPIHLGIIMVVNME
IGMLTPPVGLNLFVTAGITGRSIGWVIQSVLPWLALMLAFLALITYVPQISLFLPEFLDKLNGY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=451, Percent_Identity=28.6031042128603, Blast_Score=178, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 49397; Mature: 49265

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIATLFTALLVCMFLGMPIAIALGFSSMLTILFFSNDSLASVALKLYESSSEHYTLLAI
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHH
PFFILSSAFLSTGGVARRIIDFAMDSIGHIRGGLAMASVMACMLFAAVSGSSPATVAAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIVIVGMVKAGYPEKFAAGVITTSGTLGILIPPSIVMLVYAAATEVSAARMFMAGLIPGL
HHHHHHHHHCCCCHHHHCCEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMGFLLMIVIYIVARFKNLPSRPFPGFKQLGISSAKALGGLALIIIVLGSIYGGVASPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ASAVACMYAYFIAVFGYRDIGPLKNVAWRNPNEPIPSAIVRNLGHMALGLIKTPIDKEIR
HHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
HVVRDGAKVSIMLLFIIANAMLFAHVLTTERIPHIIAEHIVGMGLPAWGFLIIVNLLLLA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AGNFMEPSAIVLIMAPILFPIATHLGIDPIHLGIIMVVNMEIGMLTPPVGLNLFVTAGIT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEECHHCCCCCCCCCEEEEECCCC
GRSIGWVIQSVLPWLALMLAFLALITYVPQISLFLPEFLDKLNGY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIATLFTALLVCMFLGMPIAIALGFSSMLTILFFSNDSLASVALKLYESSSEHYTLLAI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHH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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]