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The map label for this gene is dctB [H]

Identifier: 117919861

GI number: 117919861

Start: 1636818

End: 1638629

Strand: Reverse

Name: dctB [H]

Synonym: Shewana3_1413

Alternate gene names: 117919861

Gene position: 1638629-1636818 (Counterclockwise)

Preceding gene: 117919862

Following gene: 117919860

Centisome position: 32.96

GC content: 49.23

Gene sequence:

>1812_bases
ATGTTGCCCATGACGCCCAAGGCCAAACAACGTCTTTTAATGACCATAGTGCTACTTGCGGGCTTATTTGCCATCTTAAA
ATTGACCTACTGGGTGCACTTTCATCAGGGCAAAATTGAAATACAACAACAATCCGAGCGACAACTCAAAGAGCTGGTTA
GCTTCTTAGATGGCGCCCTGTCGCGTTACGAGAGTATCCCCCACGTACTTTCAACTAACCCTATGCTCGCTAATGTGCTC
AACGATCAACAAAACCCCAAGAAGGTGCAAGAGCTCAACCTGTACTTGGAAGAAATTCAGCATGTCACTGAGGCATCCGA
TATCTATCTTATCGACGCCCTAGGCATTGCGATTGCCGCCAGCAACTGGCAGCAGAGTTTTTCGTTTATCGGCAAAGACT
ACTCCTTCAGACCCTATTACACCGACGCGATTTCGGGCAATTTAGGCCGCTACTATGCGGTGGGCACCAGTTCGGATAAA
CGTGGTTTTTACTTCTCTTACCCTATTTATCAGCAAGGCGCCAAAGGCATTCTGGGCGCCATTATTGTAAAAGTGGATAT
CGCCGATATCGAGCAGCAAAGCACCAGCATTGCGATGGCGGGGCAATATCAATTCCTCATCAGCGACCCCGACGATATCG
TATTTATCTCCAGTGTCGATGAATGGCGCTTAGCCTCACTCACGCCGCTAACTCAGGCCAAACAATATGCCTTAAATGCC
TCAAAACGTTACGCGGAGCGGCCGATTGGCGAATTACTGATAAAGCCACAATATCAAGAAGATAGTCTGAGTAATGGCCA
TATCTATCAAATTCGCTCCGGCAACAGTCAGGCGCAATATATGGACACCCATCATTTGATGACCAAGGCGGGTTGGCGGG
TGCATATTCTGGCGCCGATGAAACCCCTGCTCGAATCCATGCCCGCACTTATGCTGTTATCGGCCTCTATCTACTTACTG
CTCGCCTTAGGCTTACTCTTTAGTAGCGAGCGGCGCCGCAACTTGCAACGTATGCAACTCGCCCAGAGTTTACTGGAGCA
AAGAGTGGAAGAGCGCACCCAAGATCTGCAACAGGCCAATGATCGCCTCAAAGATACTCAGGATGAACTCATTCAAGCGG
CTAAGTTGACCGTGATAGGTAGCCTATCCGCCAGTATCAACCATGAACTGAATCAACCCTTAGCCGCCCTTCGCAGCTAT
GCGCAAAATACCCAGACCTTCCTCGCCCGCAATATGCCGGATAAAGCCTCTGATAACCTTAAAATTATCATCGAACTGAC
CGACCGGTTAGCCGATATTGTCGGCCAATTTAAGAGTTTTACCCGTAAGAGCCAAGGCACGGATAGCGCGACCGATCTCA
AGGGCTGTATCAAGCAAGCCCTGACCATAGTCCAGCCCGAAATCGACAAGCAAGGGGTTGAGCTCGATGTGCTGTTGCCA
GAAGGCCAATATCAGGTTTGGGGTGATAAAGTGCGATTGCAGCAAGTGTTTGTGAATATTATGAGCAACGCGATTGTCGC
CATGCAGCAATCTTCAAAACGGACACTGAGTATTAGGGTAAACTGTGCGGACAAGTTCTGTATCAGTATTCAGGACTCAG
GCCCCGGGGTGCGCGAGAGCCAGATGGAGAAGATTTTCGAGCCCTATTTCACCACCAGCGAGCGTACAGGGCTTGGTCTG
GGTTTATCCATTTCCCAGCGCATTATCGAGTCTATGCAGGGGCAAATTAATGTTGCCAATGCCGAGGACGGCGGCGCCAT
TTTCCATATTATTTTACCGATTTATTTAGCCGAGGAACGTCAGTCATCATGA

Upstream 100 bases:

>100_bases
AATCTCAAGGAATAAGGATTATTCCTTGATTCTAGATAGTTTTTAAGCGAGCCTACTCAGGCTCGCTTTGTTTTATTCAG
TGTGGACAGGATTACCTGCT

Downstream 100 bases:

>100_bases
GTCTGCCCAATTCAATTCAAGACTATAGCGTACTGATCATCGACGATGAGCCCCATATTGGCACAGTGCTCGTACAGCTT
TTTGAGCTTGAAGGCATTAA

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MLPMTPKAKQRLLMTIVLLAGLFAILKLTYWVHFHQGKIEIQQQSERQLKELVSFLDGALSRYESIPHVLSTNPMLANVL
NDQQNPKKVQELNLYLEEIQHVTEASDIYLIDALGIAIAASNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDK
RGFYFSYPIYQQGAKGILGAIIVKVDIADIEQQSTSIAMAGQYQFLISDPDDIVFISSVDEWRLASLTPLTQAKQYALNA
SKRYAERPIGELLIKPQYQEDSLSNGHIYQIRSGNSQAQYMDTHHLMTKAGWRVHILAPMKPLLESMPALMLLSASIYLL
LALGLLFSSERRRNLQRMQLAQSLLEQRVEERTQDLQQANDRLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSY
AQNTQTFLARNMPDKASDNLKIIIELTDRLADIVGQFKSFTRKSQGTDSATDLKGCIKQALTIVQPEIDKQGVELDVLLP
EGQYQVWGDKVRLQQVFVNIMSNAIVAMQQSSKRTLSIRVNCADKFCISIQDSGPGVRESQMEKIFEPYFTTSERTGLGL
GLSISQRIIESMQGQINVANAEDGGAIFHIILPIYLAEERQSS

Sequences:

>Translated_603_residues
MLPMTPKAKQRLLMTIVLLAGLFAILKLTYWVHFHQGKIEIQQQSERQLKELVSFLDGALSRYESIPHVLSTNPMLANVL
NDQQNPKKVQELNLYLEEIQHVTEASDIYLIDALGIAIAASNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDK
RGFYFSYPIYQQGAKGILGAIIVKVDIADIEQQSTSIAMAGQYQFLISDPDDIVFISSVDEWRLASLTPLTQAKQYALNA
SKRYAERPIGELLIKPQYQEDSLSNGHIYQIRSGNSQAQYMDTHHLMTKAGWRVHILAPMKPLLESMPALMLLSASIYLL
LALGLLFSSERRRNLQRMQLAQSLLEQRVEERTQDLQQANDRLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSY
AQNTQTFLARNMPDKASDNLKIIIELTDRLADIVGQFKSFTRKSQGTDSATDLKGCIKQALTIVQPEIDKQGVELDVLLP
EGQYQVWGDKVRLQQVFVNIMSNAIVAMQQSSKRTLSIRVNCADKFCISIQDSGPGVRESQMEKIFEPYFTTSERTGLGL
GLSISQRIIESMQGQINVANAEDGGAIFHIILPIYLAEERQSS
>Mature_603_residues
MLPMTPKAKQRLLMTIVLLAGLFAILKLTYWVHFHQGKIEIQQQSERQLKELVSFLDGALSRYESIPHVLSTNPMLANVL
NDQQNPKKVQELNLYLEEIQHVTEASDIYLIDALGIAIAASNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDK
RGFYFSYPIYQQGAKGILGAIIVKVDIADIEQQSTSIAMAGQYQFLISDPDDIVFISSVDEWRLASLTPLTQAKQYALNA
SKRYAERPIGELLIKPQYQEDSLSNGHIYQIRSGNSQAQYMDTHHLMTKAGWRVHILAPMKPLLESMPALMLLSASIYLL
LALGLLFSSERRRNLQRMQLAQSLLEQRVEERTQDLQQANDRLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSY
AQNTQTFLARNMPDKASDNLKIIIELTDRLADIVGQFKSFTRKSQGTDSATDLKGCIKQALTIVQPEIDKQGVELDVLLP
EGQYQVWGDKVRLQQVFVNIMSNAIVAMQQSSKRTLSIRVNCADKFCISIQDSGPGVRESQMEKIFEPYFTTSERTGLGL
GLSISQRIIESMQGQINVANAEDGGAIFHIILPIYLAEERQSS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=32.7586206896552, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=29.3617021276596, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081816, Length=326, Percent_Identity=23.9263803680982, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=28.8990825688073, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=26.5560165975104, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=127, Percent_Identity=33.0708661417323, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=26.5765765765766, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=24.3542435424354, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=24.4541484716157, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67741; Mature: 67741

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPMTPKAKQRLLMTIVLLAGLFAILKLTYWVHFHQGKIEIQQQSERQLKELVSFLDGAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEHHHHHHHHHHHHHHHHHHH
SRYESIPHVLSTNPMLANVLNDQQNPKKVQELNLYLEEIQHVTEASDIYLIDALGIAIAA
HHHHCCCHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHH
SNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDKRGFYFSYPIYQQGAKGILGA
CCHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCEEEECCHHHCCCCHHHEE
IIVKVDIADIEQQSTSIAMAGQYQFLISDPDDIVFISSVDEWRLASLTPLTQAKQYALNA
HEEEEEHHHHHHCCCCEEEECCEEEEEECCCCEEEEECCCCCHHCCCCHHHHHHHHHHHH
SKRYAERPIGELLIKPQYQEDSLSNGHIYQIRSGNSQAQYMDTHHLMTKAGWRVHILAPM
HHHHHHCCHHHHEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCH
KPLLESMPALMLLSASIYLLLALGLLFSSERRRNLQRMQLAQSLLEQRVEERTQDLQQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQNTQTFLARNMPDKASDNL
HHHCCCHHHHHHHHHHHEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KIIIELTDRLADIVGQFKSFTRKSQGTDSATDLKGCIKQALTIVQPEIDKQGVELDVLLP
EEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
EGQYQVWGDKVRLQQVFVNIMSNAIVAMQQSSKRTLSIRVNCADKFCISIQDSGPGVRES
CCCEEECCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEEEECCCCCCCHH
QMEKIFEPYFTTSERTGLGLGLSISQRIIESMQGQINVANAEDGGAIFHIILPIYLAEER
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEHHHHHHHHCC
QSS
CCC
>Mature Secondary Structure
MLPMTPKAKQRLLMTIVLLAGLFAILKLTYWVHFHQGKIEIQQQSERQLKELVSFLDGAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEHHHHHHHHHHHHHHHHHHH
SRYESIPHVLSTNPMLANVLNDQQNPKKVQELNLYLEEIQHVTEASDIYLIDALGIAIAA
HHHHCCCHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHH
SNWQQSFSFIGKDYSFRPYYTDAISGNLGRYYAVGTSSDKRGFYFSYPIYQQGAKGILGA
CCHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCEEEECCHHHCCCCHHHEE
IIVKVDIADIEQQSTSIAMAGQYQFLISDPDDIVFISSVDEWRLASLTPLTQAKQYALNA
HEEEEEHHHHHHCCCCEEEECCEEEEEECCCCEEEEECCCCCHHCCCCHHHHHHHHHHHH
SKRYAERPIGELLIKPQYQEDSLSNGHIYQIRSGNSQAQYMDTHHLMTKAGWRVHILAPM
HHHHHHCCHHHHEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCH
KPLLESMPALMLLSASIYLLLALGLLFSSERRRNLQRMQLAQSLLEQRVEERTQDLQQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLKDTQDELIQAAKLTVIGSLSASINHELNQPLAALRSYAQNTQTFLARNMPDKASDNL
HHHCCCHHHHHHHHHHHEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KIIIELTDRLADIVGQFKSFTRKSQGTDSATDLKGCIKQALTIVQPEIDKQGVELDVLLP
EEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
EGQYQVWGDKVRLQQVFVNIMSNAIVAMQQSSKRTLSIRVNCADKFCISIQDSGPGVRES
CCCEEECCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEEEECCCCCCCHH
QMEKIFEPYFTTSERTGLGLGLSISQRIIESMQGQINVANAEDGGAIFHIILPIYLAEER
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEHHHHHHHHCC
QSS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]