| Definition | Shewanella sp. ANA-3 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008577 |
| Length | 4,972,204 |
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The map label for this gene is thrA [H]
Identifier: 117919588
GI number: 117919588
Start: 1342824
End: 1345292
Strand: Direct
Name: thrA [H]
Synonym: Shewana3_1139
Alternate gene names: 117919588
Gene position: 1342824-1345292 (Clockwise)
Preceding gene: 117919585
Following gene: 117919589
Centisome position: 27.01
GC content: 50.75
Gene sequence:
>2469_bases ATGAAAGTAATGAAATTTGGTGGTACCTCGCTTGCAAATTGGCAGCGATTTTCAATGGCGGCGGATATCGTGGCCAAGGC GGCGAAAGCAGAACCTGTGGCTACAGTGCTTTCTGCGCCCGCGACAGTGACAAACGCCTTGCTAGAAATGGTGGATGTGG CGGTGAAAGGGGAAGATTATTCGCCAGTCATTCAACACGTTGAACGGGTGTTTACCTCGCTCTATCAGGATGCGGTCAGT TCTGGACTCTCGAGCAGTCAAAGCGAAGTGTTGTTCGCCGGACTGAGTGTGCAGCTTGCGCGTTGGCAGGACAGATTACG CGGTATTACGCTGCTGCAGGAATGCCCTGACGGAGTACGCGCTGAAATCGTTGTTGCTGGCGAGCGTTTGTCTGCTGCTT TGATGGAGCAAGTCATGCTGGCAAAAGGCATCACTTCGGCGCAGCTAGACCCGCGTGAGCTGTTTTTAGGTCGTGGTCGT CCGCTCGAATCCGTGGTGGATATTGCCGTCAGTAAACCGCGATTCAAAAATCTTGCCCTCGATGAAAAACGGGTTTGGGT GATGCCCGGCTTTACCGCCGCCGATGAAGACGGCAAGGTCGTGACCTTAGGCCGTAATGGCTCTGACTATTCCGCTGCCG TGCTGGCCGCTTGTTTAGATGCTTCAAGTTGTGAGATTTGGACCGACGTTGACGGCGTATACAACACCGATCCTCGGGTT GTCACCGATGCTAAATTGTTGTCACAGCTCAGTTATCAAGAGGCGATGGAGCTGTCTTACTTTGGGGCTAAGGTGCTGCA TCCTAAAACCATTGCGCCTATCGCTCAGTTCCACATCCCCTGTTATATCAAGAACAGCTTTAATCCCGATGCGCCCGGCA CTCTGGTATCGAATCAGGCCGATGAAAGCGGTCTGCAGGTGAAGGCCATTTCTAATCTGGATAATCAAACCATGTTTGAT GTTTCAGGCCCCGGCATGAAGGGCATGGTCGGCATGGCGAGCCGCACGCTGGCGGCAATTTCCCGTAGTGGCGTTTCCGT GTCACTCATCACCCAGAGTTCTTGCGAATACAGCATCAGCTTTTGTGTGGCGACTAGCGATGCGGCCAAGGTGAAATCGG CGCTGGAGCAAGAGTTTGAACTAGAAATCAAAAGTGATTTACTCGAGCCGATTGAAATGCGCCATGACTTAGCAATCGTC TCCTTGATCGGTGATGGCATGCGTACCCATAAAGGTGTGGCGGCGCGGTTCTTCCAGGCGTTAGCGCAGGCGAGTGTGAA TATCATCGCGATTGCGCAAGGCTCTTCTGAACGTTCTATTTCAACGGTAATCGAGCAGCGAAAGACCAAGCATGCGGTAG CGGCTTGTCATCAGGGCTTTTTCGATGTGCAGCAATATTTGGATGTGTTTTTAGTGGGTTGCGGCAATGTTGGCGCAGGC TTACTCGAGCAAATCAAACATCAGGCGAGCGTGTTAAAAGAGCAGCACATTAGCATTCGTGTCTGCGGCATCGTGAATTC AAGCAAGATGTTACTCGATAGTGCGGGTATCGATTTAAACAATTGGCAAAACCTGCTTGCCGACAGTCAGCAACCAAGCG ATCTTTCTGCGCTATTGGCTTGGGTGAAAGAGCAACAGTTATTAAACCCTGTGCTGGTGGATTGTACTTCAAGCGATCAA GTGTCGAACCAGTATTTAGAGGTGATGAATGCGGGCATGCACGTGGTGACGCCCAATAAGAAGGCCAATACTCGAGACTA CGCTTACTACCAAGCACTGCGTCAAACAGCCTTGAAACAACGTCGTCAGTTCCTGTATGAGACCAACGTTGGCGCCGGAT TGCCCGTTATCGATAATTTGAAAAAACTGTTATTTGCTGGCGATAAGTTACACAAGTTTAACGGTATTTTGTCAGGCTCC TTATCCTTTATCTTCGGTAAACTCGATGAGGGTATGACGCTGTCAGAAGCGACTAAACTGGCGCGGGAAAAATGCTTTAC CGAGCCCGATCCCCGTGATGATTTAAGTGGTATGGATGTGGCGCGTAAAGTGCTGATTTTGGCCCGTGAAGTGGGTTTGA AACTTGAGCTAAGCGATATCGTTGTCGACTCAGTCTTACCTGACGATTTTGATGATTCAGGCGATGTGGAAAGTTTTATG GCGCGTTTAACCGAGGCAGATGCGGCGATTGCGGCGCGAGTGGCAGAGGCGAAAGCGCAGGGTAAAGTGCTGCGTTATGT GGGGCAGATTGAAGAAGGCGCGTGTTATGTGCGTATCACCGAAGTCGATGCTACCGATCCGCTCTACAGCGTAAAAGGTG GTGAAAATGCCCTGGCATTCTACAGCCGTTATTATCAGCCGATTCCTTTTGTATTACGTGGATACGGTGCGGGTACAGAA GTGACAGCGGCCGGCGCCTTTGCCGATGTATTAAGAACCTTAAATTGGACTCGTGAGGTGAGTGTATGA
Upstream 100 bases:
>100_bases ACCCTAAAGAATTTTAACGACGAGCCCGCTTCCCACAAAGAAGCGGGCTTTTTTGTTTCTAGCTTATGTTTCTTAGTCGG GCGCGGTACAGGAGATCAAG
Downstream 100 bases:
>100_bases GTTTGACCGTTTACGCTCCCGCCTCTATGGGTAATGTGGGTGTGGGCTTTGATTTATTGGGCGCAGCACTTGCGCCCATC GATGGCAGTTTATTGGGCGA
Product: bifunctional aspartokinase I/homoserine dehydrogenase I
Products: NA
Alternate protein names: Aspartokinase I/homoserine dehydrogenase I; AKI-HDI; Aspartokinase; Homoserine dehydrogenase [H]
Number of amino acids: Translated: 822; Mature: 822
Protein sequence:
>822_residues MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDYSPVIQHVERVFTSLYQDAVS SGLSSSQSEVLFAGLSVQLARWQDRLRGITLLQECPDGVRAEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGR PLESVVDIAVSKPRFKNLALDEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADESGLQVKAISNLDNQTMFD VSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSISFCVATSDAAKVKSALEQEFELEIKSDLLEPIEMRHDLAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQPSDLSALLAWVKEQQLLNPVLVDCTSSDQ VSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQRRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGKLDEGMTLSEATKLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM ARLTEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV
Sequences:
>Translated_822_residues MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDYSPVIQHVERVFTSLYQDAVS SGLSSSQSEVLFAGLSVQLARWQDRLRGITLLQECPDGVRAEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGR PLESVVDIAVSKPRFKNLALDEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADESGLQVKAISNLDNQTMFD VSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSISFCVATSDAAKVKSALEQEFELEIKSDLLEPIEMRHDLAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQPSDLSALLAWVKEQQLLNPVLVDCTSSDQ VSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQRRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGKLDEGMTLSEATKLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM ARLTEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV >Mature_822_residues MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDYSPVIQHVERVFTSLYQDAVS SGLSSSQSEVLFAGLSVQLARWQDRLRGITLLQECPDGVRAEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGR PLESVVDIAVSKPRFKNLALDEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQADESGLQVKAISNLDNQTMFD VSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSISFCVATSDAAKVKSALEQEFELEIKSDLLEPIEMRHDLAIV SLIGDGMRTHKGVAARFFQALAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQPSDLSALLAWVKEQQLLNPVLVDCTSSDQ VSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQRRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGS LSFIFGKLDEGMTLSEATKLAREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM ARLTEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAFYSRYYQPIPFVLRGYGAGTE VTAAGAFADVLRTLNWTREVSV
Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Escherichia coli, GI1786183, Length=821, Percent_Identity=57.9780755176614, Blast_Score=945, Evalue=0.0, Organism=Escherichia coli, GI1790376, Length=816, Percent_Identity=31.25, Blast_Score=353, Evalue=2e-98, Organism=Escherichia coli, GI1790455, Length=468, Percent_Identity=29.9145299145299, Blast_Score=172, Evalue=1e-43, Organism=Saccharomyces cerevisiae, GI6322599, Length=338, Percent_Identity=32.5443786982249, Blast_Score=166, Evalue=1e-41, Organism=Saccharomyces cerevisiae, GI6320893, Length=500, Percent_Identity=24.8, Blast_Score=138, Evalue=4e-33,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005106 - InterPro: IPR001341 - InterPro: IPR018042 - InterPro: IPR011147 - InterPro: IPR001342 - InterPro: IPR019811 - InterPro: IPR016040 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT; PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]
EC number: =2.7.2.4; =1.1.1.3 [H]
Molecular weight: Translated: 89152; Mature: 89152
Theoretical pI: Translated: 5.04; Mature: 5.04
Prosite motif: PS00324 ASPARTOKINASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDY CCEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCC SPVIQHVERVFTSLYQDAVSSGLSSSQSEVLFAGLSVQLARWQDRLRGITLLQECPDGVR CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC AEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGRPLESVVDIAVSKPRFKNLAL EEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC DEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV CCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA EHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC DESGLQVKAISNLDNQTMFDVSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSIS CCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE FCVATSDAAKVKSALEQEFELEIKSDLLEPIEMRHDLAIVSLIGDGMRTHKGVAARFFQA EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQPSDLSALLA HHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHH WVKEQQLLNPVLVDCTSSDQVSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQ HHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHH RRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGKLDEGMTLSEATKL HHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHH AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCCHHHHH ARLTEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAF HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEECCCCHHHHH YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV HHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHHCCHHCCCC >Mature Secondary Structure MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDY CCEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCC SPVIQHVERVFTSLYQDAVSSGLSSSQSEVLFAGLSVQLARWQDRLRGITLLQECPDGVR CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC AEIVVAGERLSAALMEQVMLAKGITSAQLDPRELFLGRGRPLESVVDIAVSKPRFKNLAL EEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC DEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV CCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA EHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC DESGLQVKAISNLDNQTMFDVSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSIS CCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE FCVATSDAAKVKSALEQEFELEIKSDLLEPIEMRHDLAIVSLIGDGMRTHKGVAARFFQA EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADSQQPSDLSALLA HHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHH WVKEQQLLNPVLVDCTSSDQVSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQ HHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHH RRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGKLDEGMTLSEATKL HHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHH AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCCHHHHH ARLTEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAF HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEECCCCHHHHH YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV HHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHHCCHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7003595; 1630901; 7610040; 9278503; 6277952; 2410621; 387092; 6298218; 390305 [H]