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The map label for this gene is coaE [H]

Identifier: 117918873

GI number: 117918873

Start: 473729

End: 474346

Strand: Reverse

Name: coaE [H]

Synonym: Shewana3_0416

Alternate gene names: 117918873

Gene position: 474346-473729 (Counterclockwise)

Preceding gene: 117918874

Following gene: 117918872

Centisome position: 9.54

GC content: 46.12

Gene sequence:

>618_bases
ATGTCCAAGTTTGTTGTAGGTCTAACGGGTGGTATTGGTAGCGGAAAAACTACCGTTGCCAATTTATTTGCCGAAGAAGG
TGTCGATTTAGTCGATGCCGATATAGTCGCTCGCGAAGTGGTAGCAAAAGGCTCAAAAGGGCTCGAAGCCATTATCGATC
ACTTCGGCACTGAAGTATTAACCGAGGCTGGCGAGCTTGACCGAGCCAAGCTACGACAACGGGTATTTAGCGATGAACAA
CAGCGCCAATGGTTGAATCAGTTGCTCCACCCGATGATCCGCCAAGAAATGTTGTCAGAAGTCGAAAATGCGACCTCTGA
CTATGTAATTATGGTTGTACCCTTGCTATTTGAGAACGGGTTAGATAGGTTAGTCAATCGGACTTTAGTGGTGGATATTT
CGCCTGAGTTGCAAATCAGCCGTACCGTAAAACGGGACAATGTGGACGCCACTCAGGTAAATAACATCATTAATAGCCAA
TGTAGTCGCAGTGACAAACTCGCCAGAGCCGACGACATTATTGATAATCAGGGAGAGATATCAACACTAAAACAAGAGGT
GCAAGCATTGCACCAGCGCTATTTACAATTATCCGGTAATCACGACGCCCATGACTGA

Upstream 100 bases:

>100_bases
GCTATAAAAACACTGTCTATATCTTTCTTCAGTGTTTAGCATTCAATTTTGTACAGATATAGTCCAAATTGATTAGGTGC
CTTATCTAGATGGGAATCTT

Downstream 100 bases:

>100_bases
CTTAGTTTATGAACAGCCTTTAAATGAGAAAATCCGTAGCTACTTGCGGCTCGAATATCTCAATAAACAGCTCAGTAATA
ACCTAAATCACGACCACCAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSKFVVGLTGGIGSGKTTVANLFAEEGVDLVDADIVAREVVAKGSKGLEAIIDHFGTEVLTEAGELDRAKLRQRVFSDEQ
QRQWLNQLLHPMIRQEMLSEVENATSDYVIMVVPLLFENGLDRLVNRTLVVDISPELQISRTVKRDNVDATQVNNIINSQ
CSRSDKLARADDIIDNQGEISTLKQEVQALHQRYLQLSGNHDAHD

Sequences:

>Translated_205_residues
MSKFVVGLTGGIGSGKTTVANLFAEEGVDLVDADIVAREVVAKGSKGLEAIIDHFGTEVLTEAGELDRAKLRQRVFSDEQ
QRQWLNQLLHPMIRQEMLSEVENATSDYVIMVVPLLFENGLDRLVNRTLVVDISPELQISRTVKRDNVDATQVNNIINSQ
CSRSDKLARADDIIDNQGEISTLKQEVQALHQRYLQLSGNHDAHD
>Mature_204_residues
SKFVVGLTGGIGSGKTTVANLFAEEGVDLVDADIVAREVVAKGSKGLEAIIDHFGTEVLTEAGELDRAKLRQRVFSDEQQ
RQWLNQLLHPMIRQEMLSEVENATSDYVIMVVPLLFENGLDRLVNRTLVVDISPELQISRTVKRDNVDATQVNNIINSQC
SRSDKLARADDIIDNQGEISTLKQEVQALHQRYLQLSGNHDAHD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=38.5416666666667, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=38.5416666666667, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=27.1604938271605, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227605, Length=208, Percent_Identity=25, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227603, Length=208, Percent_Identity=25, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227601, Length=208, Percent_Identity=25, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI205277394, Length=208, Percent_Identity=25, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786292, Length=196, Percent_Identity=50, Blast_Score=207, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=37.037037037037, Blast_Score=130, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI25143409, Length=167, Percent_Identity=29.3413173652695, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=35.3535353535354, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644728, Length=192, Percent_Identity=29.1666666666667, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24658602, Length=186, Percent_Identity=26.3440860215054, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22792; Mature: 22661

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFVVGLTGGIGSGKTTVANLFAEEGVDLVDADIVAREVVAKGSKGLEAIIDHFGTEVL
CCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TEAGELDRAKLRQRVFSDEQQRQWLNQLLHPMIRQEMLSEVENATSDYVIMVVPLLFENG
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LDRLVNRTLVVDISPELQISRTVKRDNVDATQVNNIINSQCSRSDKLARADDIIDNQGEI
HHHHHCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
STLKQEVQALHQRYLQLSGNHDAHD
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKFVVGLTGGIGSGKTTVANLFAEEGVDLVDADIVAREVVAKGSKGLEAIIDHFGTEVL
CCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TEAGELDRAKLRQRVFSDEQQRQWLNQLLHPMIRQEMLSEVENATSDYVIMVVPLLFENG
HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LDRLVNRTLVVDISPELQISRTVKRDNVDATQVNNIINSQCSRSDKLARADDIIDNQGEI
HHHHHCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
STLKQEVQALHQRYLQLSGNHDAHD
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]