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The map label for this gene is hemX [H]

Identifier: 117918841

GI number: 117918841

Start: 444455

End: 445696

Strand: Reverse

Name: hemX [H]

Synonym: Shewana3_0384

Alternate gene names: 117918841

Gene position: 445696-444455 (Counterclockwise)

Preceding gene: 117918842

Following gene: 117918840

Centisome position: 8.96

GC content: 50.16

Gene sequence:

>1242_bases
ATGGATAACAACAAGCACGACGCCCAAAGCCCAGAGTCACAGGCTACCCCAGTTCTCGCTCCATCGGTCAATACCGATGA
CGCTGCGCCACAGACCCAAGCTTCTGAACCGCAGGTCAATCAGCTCGAAGATAAAGCCGTCAAACCTGCCGATACTCAGC
CGCAAGCCAGCAAATCCGAATCGACCCAAGCGACTCGCCAAGTGGTGCAAGTGAATCGCAGCTCATGGGCCATTCGTTTT
GGTGTGCTATTAGCATTAGGTTTAACTGCATGTACCCTCGGTGGTGGCTACTTGCTGTATCAACAAATGCAGCAACAGCT
TCAAGCGCAAATCCAAGTGCAAACCAACAAAAATCAGGCCTTGCAGGATCAATTACAACAAGCCTTACTCGCCCCGAATC
AGCGCATTGCGCAGCTTGAGCAACAACAACTGTCAAATACCAAAACCTTCCAAGAGCTCGCCAAACTCGCCTCGGACCAA
AGTCAGTTGCAGGACAGGTTAAATAAGCTGGCCCAACGCAGCCCAACCCACTGGATGGCCTCGGAAGCCGAATACTTAGT
AAATATGGCGGGACGTAAGCTTTGGCTCGAAAAAGATCCACGCACGGCAACCGACTTACTAAAGTCAGCCGACGAAACCA
TTGCCGCAATGAATAACCCTGCTTTACTGCCAATCCGTAAGGCGCTGGCCAAGGATATTGCCGCGACCACCAATATTAAA
AGTGCGGATATTGAAGGCAGCGTATTAGCTCTCGATACCTTAATCGACCAACTCGACAAGTTGCCCCTCAGCCGCGCGGA
TGCTGATGCAAGCGCCCCTGAAGATACTACCATTTCTGGCGATCTGAATGATTGGCAAAGTAACCTAAGTAAAACTTGGA
AAGCGTTAACCCAAGATTTTGTTACCATTCGCCACAGAACCGCCGATGCGCCTGCCCTGCTCGCACCGGAGCAACAATGG
TATTTGGTCGAGAATATTCGCCATAAGCTGCTGCAATCTCAACTGGCGCTCTATCGCTATGATAGAGCGGCTTATCATCA
ATCACTGATGATGGCGCGCCAGTGGATCCAAACCTATTTTGATGTTCAAGCCCACCCAACCAGTGAAGCCATTGCCGAGA
TAGACAAACTGGCGACATTAGAGCTTGACCCTATTACGCTGAAATCCTTTGCCGCTAAACCACTGTTATTACAGTTAACC
AGCTATGGTGAACTCACCTCTTCAGAGGAACCACAGCTATGA

Upstream 100 bases:

>100_bases
CGCCAACAGCAAAGCCGTGCTAAACGCCCTTAAACTCTAAGCGCTATTTAGCCCGATTTTACTCGAATTTCGGCAGTAGC
ATGATTTTAAGGACTGTTAA

Downstream 100 bases:

>100_bases
TTAAGGCATTGATATTTCTTGGGATCATATTAATAGGCCTGTGTATCAGCCCTTGGATTGTCGGCAATACTGGCTATGTG
TATATTGCCGCTGGCGATTA

Product: hypothetical protein

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MDNNKHDAQSPESQATPVLAPSVNTDDAAPQTQASEPQVNQLEDKAVKPADTQPQASKSESTQATRQVVQVNRSSWAIRF
GVLLALGLTACTLGGGYLLYQQMQQQLQAQIQVQTNKNQALQDQLQQALLAPNQRIAQLEQQQLSNTKTFQELAKLASDQ
SQLQDRLNKLAQRSPTHWMASEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATTNIK
SADIEGSVLALDTLIDQLDKLPLSRADADASAPEDTTISGDLNDWQSNLSKTWKALTQDFVTIRHRTADAPALLAPEQQW
YLVENIRHKLLQSQLALYRYDRAAYHQSLMMARQWIQTYFDVQAHPTSEAIAEIDKLATLELDPITLKSFAAKPLLLQLT
SYGELTSSEEPQL

Sequences:

>Translated_413_residues
MDNNKHDAQSPESQATPVLAPSVNTDDAAPQTQASEPQVNQLEDKAVKPADTQPQASKSESTQATRQVVQVNRSSWAIRF
GVLLALGLTACTLGGGYLLYQQMQQQLQAQIQVQTNKNQALQDQLQQALLAPNQRIAQLEQQQLSNTKTFQELAKLASDQ
SQLQDRLNKLAQRSPTHWMASEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATTNIK
SADIEGSVLALDTLIDQLDKLPLSRADADASAPEDTTISGDLNDWQSNLSKTWKALTQDFVTIRHRTADAPALLAPEQQW
YLVENIRHKLLQSQLALYRYDRAAYHQSLMMARQWIQTYFDVQAHPTSEAIAEIDKLATLELDPITLKSFAAKPLLLQLT
SYGELTSSEEPQL
>Mature_413_residues
MDNNKHDAQSPESQATPVLAPSVNTDDAAPQTQASEPQVNQLEDKAVKPADTQPQASKSESTQATRQVVQVNRSSWAIRF
GVLLALGLTACTLGGGYLLYQQMQQQLQAQIQVQTNKNQALQDQLQQALLAPNQRIAQLEQQQLSNTKTFQELAKLASDQ
SQLQDRLNKLAQRSPTHWMASEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATTNIK
SADIEGSVLALDTLIDQLDKLPLSRADADASAPEDTTISGDLNDWQSNLSKTWKALTQDFVTIRHRTADAPALLAPEQQW
YLVENIRHKLLQSQLALYRYDRAAYHQSLMMARQWIQTYFDVQAHPTSEAIAEIDKLATLELDPITLKSFAAKPLLLQLT
SYGELTSSEEPQL

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=249, Percent_Identity=36.5461847389558, Blast_Score=161, Evalue=6e-41,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 45844; Mature: 45844

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNKHDAQSPESQATPVLAPSVNTDDAAPQTQASEPQVNQLEDKAVKPADTQPQASKSE
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHH
STQATRQVVQVNRSSWAIRFGVLLALGLTACTLGGGYLLYQQMQQQLQAQIQVQTNKNQA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCHH
LQDQLQQALLAPNQRIAQLEQQQLSNTKTFQELAKLASDQSQLQDRLNKLAQRSPTHWMA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHH
SEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATTNIK
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
SADIEGSVLALDTLIDQLDKLPLSRADADASAPEDTTISGDLNDWQSNLSKTWKALTQDF
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
VTIRHRTADAPALLAPEQQWYLVENIRHKLLQSQLALYRYDRAAYHQSLMMARQWIQTYF
HHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVQAHPTSEAIAEIDKLATLELDPITLKSFAAKPLLLQLTSYGELTSSEEPQL
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MDNNKHDAQSPESQATPVLAPSVNTDDAAPQTQASEPQVNQLEDKAVKPADTQPQASKSE
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHH
STQATRQVVQVNRSSWAIRFGVLLALGLTACTLGGGYLLYQQMQQQLQAQIQVQTNKNQA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCHH
LQDQLQQALLAPNQRIAQLEQQQLSNTKTFQELAKLASDQSQLQDRLNKLAQRSPTHWMA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHH
SEAEYLVNMAGRKLWLEKDPRTATDLLKSADETIAAMNNPALLPIRKALAKDIAATTNIK
HHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
SADIEGSVLALDTLIDQLDKLPLSRADADASAPEDTTISGDLNDWQSNLSKTWKALTQDF
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
VTIRHRTADAPALLAPEQQWYLVENIRHKLLQSQLALYRYDRAAYHQSLMMARQWIQTYF
HHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVQAHPTSEAIAEIDKLATLELDPITLKSFAAKPLLLQLTSYGELTSSEEPQL
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]