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The map label for this gene is hemY [H]

Identifier: 117918840

GI number: 117918840

Start: 443292

End: 444458

Strand: Reverse

Name: hemY [H]

Synonym: Shewana3_0383

Alternate gene names: 117918840

Gene position: 444458-443292 (Counterclockwise)

Preceding gene: 117918841

Following gene: 117918839

Centisome position: 8.94

GC content: 48.24

Gene sequence:

>1167_bases
ATGATTAAGGCATTGATATTTCTTGGGATCATATTAATAGGCCTGTGTATCAGCCCTTGGATTGTCGGCAATACTGGCTA
TGTGTATATTGCCGCTGGCGATTATCAGCTTGAGACCAGTTTAGTCTTTGGGATCATCATGTTAATCGTGTTCTATGCTC
TGTTCCAAGTGCTGGAATGGCTAGTGATCACTGTGATTAATTTGCTGCTTCGAAGCCGTTTTATCCCTCAGCATTGGCGT
CGCCGCTCCGCAAAGAAACACACCCTAATCGGCGCACTCGCCATTGCCGAAGAGGATTGGCCAGCGGCTGAACGCGCCAT
GATTAAAGGGGCTGACAATGGTGAACTGCCAGCATTAAATTTGTTAGCCGCCGCACGTGCTGCGCAACATCAAAATAAAA
TCGCCGAGCGAGATCAATATCTTGCCCGCGCCGAAGCCCAACCTATGACGGCCAATGCGGTAGCGACTACTCGTACACGT
TACTTGCTCAAGCAAGGGGAACTCGCCTTAGCCAGAGCGGAACTTGATAAGTTAGCCCCAACCAGCAAGAGTAAAGCACC
TGTGCTGAAACTCGCCCTAGAATTGTACCGGGCGCAAGAAGATTGGGAGGCGCTTAAGCTGTTGCTCCCAATACTGAAGA
AACGGCAGATCTTAGAGGATGCCAAGCTAAATGCACTCAGCGTTGAAACCCATTGCGCCCTGTTAAAAGCAGCGAGTCTT
AAAGGGGAAGATGCCCTAGAGCAATGCTGGCAATGGCTTTCACGTGATGAACGTAACCAGTCTGAGTTTTTAGCGATTTA
CGCCATGGGCTTATGCCGCTTTAATCGTAAAGACCAGGCGCTTAAATTACTCTCGAAAAAGCTACGTAGCTCGCCTGAGT
CGGCACTGTTAGAAGTAATACCACAAATAGTCACTGCCCATGACGAAGAGATCCGCAAGCAATTACTCAAACATGAAATC
ACCCATGAGAATAATGCTGATTACCAAAAGTGCTTAGCGCTGTTGTATCAACAAACCCGCGATATGAAAGAAGCTAAAAC
CTGCTGGCAGAATGTTTGTCGTCTCGCCCCAAGCCAAGCGTCTTGGTTATCGCTTGCCCGTATTCAAGAACAACTCGGCG
AACAAGGTAACGCAAATCAAAGCTATCGCCAGGCGGTTAACCTGTAA

Upstream 100 bases:

>100_bases
TAGAGCTTGACCCTATTACGCTGAAATCCTTTGCCGCTAAACCACTGTTATTACAGTTAACCAGCTATGGTGAACTCACC
TCTTCAGAGGAACCACAGCT

Downstream 100 bases:

>100_bases
TTTGCTATAGCCGCAGCTCCTCTATCGGAGTTGCGGCCCCTCAAAACTAACCAATCACTTCCTTTTTAGCTCGCCTAAAC
GCCGTTTTAGCAGAATTCAT

Product: HemY domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIKALIFLGIILIGLCISPWIVGNTGYVYIAAGDYQLETSLVFGIIMLIVFYALFQVLEWLVITVINLLLRSRFIPQHWR
RRSAKKHTLIGALAIAEEDWPAAERAMIKGADNGELPALNLLAAARAAQHQNKIAERDQYLARAEAQPMTANAVATTRTR
YLLKQGELALARAELDKLAPTSKSKAPVLKLALELYRAQEDWEALKLLLPILKKRQILEDAKLNALSVETHCALLKAASL
KGEDALEQCWQWLSRDERNQSEFLAIYAMGLCRFNRKDQALKLLSKKLRSSPESALLEVIPQIVTAHDEEIRKQLLKHEI
THENNADYQKCLALLYQQTRDMKEAKTCWQNVCRLAPSQASWLSLARIQEQLGEQGNANQSYRQAVNL

Sequences:

>Translated_388_residues
MIKALIFLGIILIGLCISPWIVGNTGYVYIAAGDYQLETSLVFGIIMLIVFYALFQVLEWLVITVINLLLRSRFIPQHWR
RRSAKKHTLIGALAIAEEDWPAAERAMIKGADNGELPALNLLAAARAAQHQNKIAERDQYLARAEAQPMTANAVATTRTR
YLLKQGELALARAELDKLAPTSKSKAPVLKLALELYRAQEDWEALKLLLPILKKRQILEDAKLNALSVETHCALLKAASL
KGEDALEQCWQWLSRDERNQSEFLAIYAMGLCRFNRKDQALKLLSKKLRSSPESALLEVIPQIVTAHDEEIRKQLLKHEI
THENNADYQKCLALLYQQTRDMKEAKTCWQNVCRLAPSQASWLSLARIQEQLGEQGNANQSYRQAVNL
>Mature_388_residues
MIKALIFLGIILIGLCISPWIVGNTGYVYIAAGDYQLETSLVFGIIMLIVFYALFQVLEWLVITVINLLLRSRFIPQHWR
RRSAKKHTLIGALAIAEEDWPAAERAMIKGADNGELPALNLLAAARAAQHQNKIAERDQYLARAEAQPMTANAVATTRTR
YLLKQGELALARAELDKLAPTSKSKAPVLKLALELYRAQEDWEALKLLLPILKKRQILEDAKLNALSVETHCALLKAASL
KGEDALEQCWQWLSRDERNQSEFLAIYAMGLCRFNRKDQALKLLSKKLRSSPESALLEVIPQIVTAHDEEIRKQLLKHEI
THENNADYQKCLALLYQQTRDMKEAKTCWQNVCRLAPSQASWLSLARIQEQLGEQGNANQSYRQAVNL

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790234, Length=308, Percent_Identity=29.8701298701299, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07219 HemY_N [H]

EC number: NA

Molecular weight: Translated: 43875; Mature: 43875

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKALIFLGIILIGLCISPWIVGNTGYVYIAAGDYQLETSLVFGIIMLIVFYALFQVLEW
CHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVITVINLLLRSRFIPQHWRRRSAKKHTLIGALAIAEEDWPAAERAMIKGADNGELPALN
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHH
LLAAARAAQHQNKIAERDQYLARAEAQPMTANAVATTRTRYLLKQGELALARAELDKLAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
TSKSKAPVLKLALELYRAQEDWEALKLLLPILKKRQILEDAKLNALSVETHCALLKAASL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCC
KGEDALEQCWQWLSRDERNQSEFLAIYAMGLCRFNRKDQALKLLSKKLRSSPESALLEVI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHH
PQIVTAHDEEIRKQLLKHEITHENNADYQKCLALLYQQTRDMKEAKTCWQNVCRLAPSQA
HHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SWLSLARIQEQLGEQGNANQSYRQAVNL
HHHHHHHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MIKALIFLGIILIGLCISPWIVGNTGYVYIAAGDYQLETSLVFGIIMLIVFYALFQVLEW
CHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVITVINLLLRSRFIPQHWRRRSAKKHTLIGALAIAEEDWPAAERAMIKGADNGELPALN
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHH
LLAAARAAQHQNKIAERDQYLARAEAQPMTANAVATTRTRYLLKQGELALARAELDKLAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
TSKSKAPVLKLALELYRAQEDWEALKLLLPILKKRQILEDAKLNALSVETHCALLKAASL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCC
KGEDALEQCWQWLSRDERNQSEFLAIYAMGLCRFNRKDQALKLLSKKLRSSPESALLEVI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHH
PQIVTAHDEEIRKQLLKHEITHENNADYQKCLALLYQQTRDMKEAKTCWQNVCRLAPSQA
HHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SWLSLARIQEQLGEQGNANQSYRQAVNL
HHHHHHHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]