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The map label for this gene is msrB [H]

Identifier: 117676263

GI number: 117676263

Start: 215589

End: 216035

Strand: Reverse

Name: msrB [H]

Synonym: Shewana3_4326

Alternate gene names: 117676263

Gene position: 216035-215589 (Counterclockwise)

Preceding gene: 117676264

Following gene: 117676262

Centisome position: 77.45

GC content: 45.64

Gene sequence:

>447_bases
ATGAATACCTATCAAAAATCTATGAATGCGATTTCTGCTCTGACTAAGGAGCAGTATCGGGTGACGCAAGAAAATGGTAC
AGAGCGTCCAGGGACTGGTGAATTGCTAAAGAACACCAAGCCCGGCATTTACGTGGATATCGTGTCAGGTGAGCCTTTAT
TTGCGTCTTCTGCCAAGTATGAATCAGGGTGTGGTTGGCCGAGCTTTACCAAAGCGATAGACTCTGTCAACGTAATTGAA
ATCACTGATAGGTCGCACGGCATGACCCGCACAGAAGTGCGCTCAACTCATGGCGACAGTCACTTAGGCCATGTATTTTC
AGACGGTCCCAAAGACCAGGGTGGCCTACGTTATTGTATTAACTCAGCGTCATTACGTTTTATTCCTAGGGAAGAAATGG
CAAGTAAAGGTTACGCAGAGTATTTAGACCAAGTAGAGGACATTTAA

Upstream 100 bases:

>100_bases
TCATTTTTTCGGGTTAACGGCCTAAGTGAAATAAATTCTGTAAACAGAAGGTCTCTTATAATCTGAAAGGCACATGGCTC
TACTCTATAAGAGGACATTT

Downstream 100 bases:

>100_bases
TTATGGCAATTGAACGCGCAGTATTAGCCGGTGGCTGCTTTTGGGGCATGCAGGATCTTATCCGCAAACGTCCCGGTATC
ACTTCAACCCGAGTAGGTTA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MNTYQKSMNAISALTKEQYRVTQENGTERPGTGELLKNTKPGIYVDIVSGEPLFASSAKYESGCGWPSFTKAIDSVNVIE
ITDRSHGMTRTEVRSTHGDSHLGHVFSDGPKDQGGLRYCINSASLRFIPREEMASKGYAEYLDQVEDI

Sequences:

>Translated_148_residues
MNTYQKSMNAISALTKEQYRVTQENGTERPGTGELLKNTKPGIYVDIVSGEPLFASSAKYESGCGWPSFTKAIDSVNVIE
ITDRSHGMTRTEVRSTHGDSHLGHVFSDGPKDQGGLRYCINSASLRFIPREEMASKGYAEYLDQVEDI
>Mature_148_residues
MNTYQKSMNAISALTKEQYRVTQENGTERPGTGELLKNTKPGIYVDIVSGEPLFASSAKYESGCGWPSFTKAIDSVNVIE
ITDRSHGMTRTEVRSTHGDSHLGHVFSDGPKDQGGLRYCINSASLRFIPREEMASKGYAEYLDQVEDI

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=48.8188976377953, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=48.8188976377953, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=48.8188976377953, Blast_Score=117, Evalue=5e-27,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=48.8188976377953, Blast_Score=116, Evalue=9e-27,
Organism=Homo sapiens, GI117606353, Length=125, Percent_Identity=44.8, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788077, Length=114, Percent_Identity=52.6315789473684, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17553450, Length=117, Percent_Identity=51.2820512820513, Blast_Score=128, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=117, Percent_Identity=51.2820512820513, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=123, Percent_Identity=35.7723577235772, Blast_Score=78, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221378664, Length=116, Percent_Identity=50.8620689655172, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221378662, Length=123, Percent_Identity=45.5284552845528, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24645799, Length=116, Percent_Identity=50.8620689655172, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45553335, Length=116, Percent_Identity=50.8620689655172, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356369, Length=116, Percent_Identity=50.8620689655172, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24645801, Length=127, Percent_Identity=46.4566929133858, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24645804, Length=127, Percent_Identity=46.4566929133858, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16370; Mature: 16370

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTYQKSMNAISALTKEQYRVTQENGTERPGTGELLKNTKPGIYVDIVSGEPLFASSAKY
CCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCC
ESGCGWPSFTKAIDSVNVIEITDRSHGMTRTEVRSTHGDSHLGHVFSDGPKDQGGLRYCI
CCCCCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFIPREEMASKGYAEYLDQVEDI
CCCCEEEECHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MNTYQKSMNAISALTKEQYRVTQENGTERPGTGELLKNTKPGIYVDIVSGEPLFASSAKY
CCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCC
ESGCGWPSFTKAIDSVNVIEITDRSHGMTRTEVRSTHGDSHLGHVFSDGPKDQGGLRYCI
CCCCCCCHHHHHHCCCCEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFIPREEMASKGYAEYLDQVEDI
CCCCEEEECHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]