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The map label for this gene is msrA [H]

Identifier: 117676261

GI number: 117676261

Start: 214517

End: 215089

Strand: Reverse

Name: msrA [H]

Synonym: Shewana3_4324

Alternate gene names: 117676261

Gene position: 215089-214517 (Counterclockwise)

Preceding gene: 117676262

Following gene: 117676259

Centisome position: 77.11

GC content: 41.01

Gene sequence:

>573_bases
ATGAGTTTGCAGCAGCCCACACAGACTTGCAATTTGCATACGACAACCACCCTTAATACAATCGGCTTAGGCGGTGGTTG
TCACTGGTGCACCGAAGGCGTATTTTCATCACTTATTGGCATTGCTACTGTCAATCAAGGTTGGATCGCCTCAATTGGTG
ACAACGCTCAGTTCAGCGAAGCCATTGAAGTGGTTTTTGATCCGACTGTTATTTCTTTATCAACCTTGATCGAAATCCAT
TTACATACTCACGCGAGCACATCAAACCACTCAATGCGTGGTAAATATCGTTCAGCGATATACGCTTATGATGAGGTTCA
GTATAACCAGGCTGTAAACATATTAGATGCCTGTAGAGCTGATTTTGAGCAGCCAGTCATTACTCAGGTTTATTTTTTTA
AGGATTTTAAAGCGAATAAAACTGAGCTTATCGACTACTTTTATACAGCACCCAACAGACCATTTTGTCAAAGGTACATT
CATCCAAAACTCACCTTCTTATTAGCACGTTTCAGCCACTATGTTGATACGCATAAATTGACAGAGTCAGGTGTAGAGTT
AACATCGATATAG

Upstream 100 bases:

>100_bases
TTTGGGAAGCGGAGGCTATGCATCAGGACTATTTGGAACTCCGACCAAATGGCTATACCTGCCACTTCCCCAGACCAGAC
TGGAAGTTGCCCTCATCTCA

Downstream 100 bases:

>100_bases
GCTGTGCTACTCTGCAAGTTCGAGCGTCATGATTACCAACTCTAGTAGTGGCATCGATCACACGAAAACTAAAACGATGT
CACCGCAAACGAATGGGATC

Product: methionine sulfoxide reductase A

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSLQQPTQTCNLHTTTTLNTIGLGGGCHWCTEGVFSSLIGIATVNQGWIASIGDNAQFSEAIEVVFDPTVISLSTLIEIH
LHTHASTSNHSMRGKYRSAIYAYDEVQYNQAVNILDACRADFEQPVITQVYFFKDFKANKTELIDYFYTAPNRPFCQRYI
HPKLTFLLARFSHYVDTHKLTESGVELTSI

Sequences:

>Translated_190_residues
MSLQQPTQTCNLHTTTTLNTIGLGGGCHWCTEGVFSSLIGIATVNQGWIASIGDNAQFSEAIEVVFDPTVISLSTLIEIH
LHTHASTSNHSMRGKYRSAIYAYDEVQYNQAVNILDACRADFEQPVITQVYFFKDFKANKTELIDYFYTAPNRPFCQRYI
HPKLTFLLARFSHYVDTHKLTESGVELTSI
>Mature_189_residues
SLQQPTQTCNLHTTTTLNTIGLGGGCHWCTEGVFSSLIGIATVNQGWIASIGDNAQFSEAIEVVFDPTVISLSTLIEIHL
HTHASTSNHSMRGKYRSAIYAYDEVQYNQAVNILDACRADFEQPVITQVYFFKDFKANKTELIDYFYTAPNRPFCQRYIH
PKLTFLLARFSHYVDTHKLTESGVELTSI

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 21391; Mature: 21260

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQQPTQTCNLHTTTTLNTIGLGGGCHWCTEGVFSSLIGIATVNQGWIASIGDNAQFSE
CCCCCCCCCCCCEEECEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHH
AIEVVFDPTVISLSTLIEIHLHTHASTSNHSMRGKYRSAIYAYDEVQYNQAVNILDACRA
HHHHHCCCHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHHH
DFEQPVITQVYFFKDFKANKTELIDYFYTAPNRPFCQRYIHPKLTFLLARFSHYVDTHKL
CCCCCHHHHEEEECCCCCCHHHHHHHEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
TESGVELTSI
HHCCCEEECC
>Mature Secondary Structure 
SLQQPTQTCNLHTTTTLNTIGLGGGCHWCTEGVFSSLIGIATVNQGWIASIGDNAQFSE
CCCCCCCCCCCEEECEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHH
AIEVVFDPTVISLSTLIEIHLHTHASTSNHSMRGKYRSAIYAYDEVQYNQAVNILDACRA
HHHHHCCCHHHHHHHEEEEEEEECCCCCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHHH
DFEQPVITQVYFFKDFKANKTELIDYFYTAPNRPFCQRYIHPKLTFLLARFSHYVDTHKL
CCCCCHHHHEEEECCCCCCHHHHHHHEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
TESGVELTSI
HHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA