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The map label for this gene is blaR1 [H]

Identifier: 116871636

GI number: 116871636

Start: 223889

End: 224950

Strand: Direct

Name: blaR1 [H]

Synonym: lwe0216

Alternate gene names: 116871636

Gene position: 223889-224950 (Clockwise)

Preceding gene: 116871635

Following gene: 116871637

Centisome position: 7.96

GC content: 29.47

Gene sequence:

>1062_bases
ATGAATGAACTGCTTAAGATGGTCTTATCCATGGCCCTCACTTCACTAGTGTTAATACCATGTATATGGATATTTGGAAA
AGCATTTAATCGCTATTTAAGTAAGAAAAAAATCTATTATTTATGGCTTGTTGTTTTTCTCTTTTTAACAATACCTTTTT
CATTTATTTTCTTTACGCCAACAAAAAATAATGAATTTATGTGGGGAAAAGGAACCGGTTTAGAAGGAGCTACTTCAGTT
GTATTTGATAACAATGGTATTTTTGTAGAAAGAGATGCTAAAGTTGCTTTTTGGATGACATTACTCGATTATTTATGGGT
AATTTGGTTGGTAATATTTTTACTTATTTTTATTTACAGAATCGCTTCTTATCGAAATTTTAAAAAATATGTTTTTTCAG
GCGCACAAAAAGTAAATAATTTGGAGCAACTTGATCAATTAGGGGAGATTATAGATGAATTAAATATTAAAAAATCAGTT
GAACTGATGATTAATCCACTAATTTCTTCACCTATTTTCTTAGGATTCAAGCGAAATGTTATAGTGTTACCTGATAAATC
TTTTTCTGAAGAGGAACTTCAATATATTCTTAGACACGAGTTAATACATTGTAAACGAAAAGACATGTATTATGTCTGGA
TTGCTCAATTTTTCGTTTGTATCTATTGGTTCAATCCTCTGGTGTATCTTATGAATAAACAAATCCAAATTGATCGTGAA
TTAGCTTGTGACGAAGCGGTTTTAGCTACCCTGCCAAAAGAGAAATATTTGGGTTATGGAGATACATTACTCTCTTCGCT
TGCAAAATCAGGAAACTATAAAGAATCATCCGTAGCCGTTTCACTTCACGAAAATACTAAAAAGTTAAAAGAAAGGCTTA
CATTCATTGCAAATTATCAAAAGGAAGCAAAAAATAATAACACAATTTTACCTATTTTTCTGATAGCACTATGTAGTGTA
GGTCTAATATTTAGTTTGTTTCAAACAGAAATATTCACTAAAGAAAAGAACAAATCCATTATAATTAAGAAAGATAAAAA
TACAAATAACTTCTCTCGTTAA

Upstream 100 bases:

>100_bases
GATGTAAAAGGATTAATCACGAATTTAGTACAGAATGACTTAATTTCTTCGGATGAACTTGATGATTTACAACAATTTTG
GAAAAGGATGAAGTCACCTA

Downstream 100 bases:

>100_bases
TTGAGGGAAGTTTTTTTGTGTAAGATATTGACTTTTAAGCCTACAAAATGTAGAATTAAAATGCATAAATAATACTAAAA
AAGGTGGGGGAATTACATGT

Product: peptidase M56 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNELLKMVLSMALTSLVLIPCIWIFGKAFNRYLSKKKIYYLWLVVFLFLTIPFSFIFFTPTKNNEFMWGKGTGLEGATSV
VFDNNGIFVERDAKVAFWMTLLDYLWVIWLVIFLLIFIYRIASYRNFKKYVFSGAQKVNNLEQLDQLGEIIDELNIKKSV
ELMINPLISSPIFLGFKRNVIVLPDKSFSEEELQYILRHELIHCKRKDMYYVWIAQFFVCIYWFNPLVYLMNKQIQIDRE
LACDEAVLATLPKEKYLGYGDTLLSSLAKSGNYKESSVAVSLHENTKKLKERLTFIANYQKEAKNNNTILPIFLIALCSV
GLIFSLFQTEIFTKEKNKSIIIKKDKNTNNFSR

Sequences:

>Translated_353_residues
MNELLKMVLSMALTSLVLIPCIWIFGKAFNRYLSKKKIYYLWLVVFLFLTIPFSFIFFTPTKNNEFMWGKGTGLEGATSV
VFDNNGIFVERDAKVAFWMTLLDYLWVIWLVIFLLIFIYRIASYRNFKKYVFSGAQKVNNLEQLDQLGEIIDELNIKKSV
ELMINPLISSPIFLGFKRNVIVLPDKSFSEEELQYILRHELIHCKRKDMYYVWIAQFFVCIYWFNPLVYLMNKQIQIDRE
LACDEAVLATLPKEKYLGYGDTLLSSLAKSGNYKESSVAVSLHENTKKLKERLTFIANYQKEAKNNNTILPIFLIALCSV
GLIFSLFQTEIFTKEKNKSIIIKKDKNTNNFSR
>Mature_353_residues
MNELLKMVLSMALTSLVLIPCIWIFGKAFNRYLSKKKIYYLWLVVFLFLTIPFSFIFFTPTKNNEFMWGKGTGLEGATSV
VFDNNGIFVERDAKVAFWMTLLDYLWVIWLVIFLLIFIYRIASYRNFKKYVFSGAQKVNNLEQLDQLGEIIDELNIKKSV
ELMINPLISSPIFLGFKRNVIVLPDKSFSEEELQYILRHELIHCKRKDMYYVWIAQFFVCIYWFNPLVYLMNKQIQIDRE
LACDEAVLATLPKEKYLGYGDTLLSSLAKSGNYKESSVAVSLHENTKKLKERLTFIANYQKEAKNNNTILPIFLIALCSV
GLIFSLFQTEIFTKEKNKSIIIKKDKNTNNFSR

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 41296; Mature: 41296

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELLKMVLSMALTSLVLIPCIWIFGKAFNRYLSKKKIYYLWLVVFLFLTIPFSFIFFTP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TKNNEFMWGKGTGLEGATSVVFDNNGIFVERDAKVAFWMTLLDYLWVIWLVIFLLIFIYR
CCCCCEEECCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASYRNFKKYVFSGAQKVNNLEQLDQLGEIIDELNIKKSVELMINPLISSPIFLGFKRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCE
IVLPDKSFSEEELQYILRHELIHCKRKDMYYVWIAQFFVCIYWFNPLVYLMNKQIQIDRE
EEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LACDEAVLATLPKEKYLGYGDTLLSSLAKSGNYKESSVAVSLHENTKKLKERLTFIANYQ
HHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
KEAKNNNTILPIFLIALCSVGLIFSLFQTEIFTKEKNKSIIIKKDKNTNNFSR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MNELLKMVLSMALTSLVLIPCIWIFGKAFNRYLSKKKIYYLWLVVFLFLTIPFSFIFFTP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
TKNNEFMWGKGTGLEGATSVVFDNNGIFVERDAKVAFWMTLLDYLWVIWLVIFLLIFIYR
CCCCCEEECCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASYRNFKKYVFSGAQKVNNLEQLDQLGEIIDELNIKKSVELMINPLISSPIFLGFKRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCE
IVLPDKSFSEEELQYILRHELIHCKRKDMYYVWIAQFFVCIYWFNPLVYLMNKQIQIDRE
EEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LACDEAVLATLPKEKYLGYGDTLLSSLAKSGNYKESSVAVSLHENTKKLKERLTFIANYQ
HHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
KEAKNNNTILPIFLIALCSVGLIFSLFQTEIFTKEKNKSIIIKKDKNTNNFSR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]