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The map label for this gene is yoeA [H]

Identifier: 116871425

GI number: 116871425

Start: 3120

End: 4463

Strand: Direct

Name: yoeA [H]

Synonym: lwe0003

Alternate gene names: 116871425

Gene position: 3120-4463 (Clockwise)

Preceding gene: 116871424

Following gene: 116871426

Centisome position: 0.11

GC content: 37.35

Gene sequence:

>1344_bases
ATGATGAAAGATATGACAACAGGTAATCCAACAAAATTAATCTTTTTATTTGCGATGCCGATGTTAATTGGAAACTTGTT
TCAGCAGTTTTATACGATGATTGATGCGGTTATTGTTGGAAAATTTGTAAGTGTAGACGCGCTTGCAGCTGTTGGTGCGA
CAAATTCAGTCAATTTTTTTATGATTTCTTTGATTATTGGACTTATGAGCGGTATTTCTGTCGTAGTAGCTCAGTATTTT
GGTTTTAAAGATTATGATCGTTTAAAAGATGTTATCGCTACAGCAACCTATGCGGTGGTTTTTTCGGCGATTATTTTGAC
AGTTGCAGGAGTGTTACTTGCGAAGCCCTTACTTATTTTACTTAGAACACCAGCTAATATTTTAGATGATTCAACTATTT
TTTTGACTACTCTTTTTATTGGAATTTTACCAATGAGTTTGTATAACGGGATGGCAGCGATTTTGCGGGCCCTTGGAAAT
TCCATCACTCCACTGATTTTTTTGATTTTATCTTCGTTACTTAATATTGCGCTTGATTTTTTATTTGTCGTTTATATGGG
TATGGGCGTTCGTGGAGCTGCGATTGCAACAGTTTTATCACAAGCTGGGGCAGCAATAGCCGTTATTTATTATGCTTATC
GGCATGTACCTTTTATGAAAATAGAGCGTTCCAGATTTAAGTTATCTACCCCTTTACTTAAGGAAATGGTGCGAATTGGA
CTTCCTTCAGGGTTACAAGGATCATTTATTTCTATCGGAAATATGGCGCTTCAAAGTTTAATTAATGGTTTTGGTTCGTC
CGTTGTTGCGGCGTATACTGCAGCTAGTCGAATTGATTCACTTACATATCAACCTGGAATTGCCTTTGGAGCTGCATCTT
CCATGTTTGCTGGTCAAAATATTGGTGCAGGAAAATTGGACCGCGTTCGCGAAGGTTTTTGGTCAGGAATTAAAGTAGTT
ACTGTTATCAGTATTGGAATTACGATTTTAGTTCAACTTTTTGCGCGTCAATTTTTATTATTATTTGTAGACTCTAGTGA
GACGGAAGTTATTAATATTGGCGTGAGTTATTTACTTATTGTGTCGTTATTTTATGTTGTAGTTGGTATTTTGTTTGTCG
TGCGGGAAACATTACGTGGTACGGGAGATGCGATGGTTCCTTTAGCAATGGGCATTTTCGAATTGGTTTCACGGCTTGTA
ATTGGATTTGTTTTATCTCTTTACATTGGTTATGTTGGACTGTGGTGGGCGACACCTGTTGCATGGATTACTGCGACGAT
GCTAGGAGTTTGGCGATATAAATCTGGAACTTGGCAAAAAAAAGCAGTTATCAGGCGAAAATAA

Upstream 100 bases:

>100_bases
AAAAAGCACATCCGTCTTGGTTTCAAGGCGGATTCTTTTTTTGTTATAGTACAGTTTTTTAGAAAAAATGTATATTTATG
CAAACGGGGGTAATTTTAAC

Downstream 100 bases:

>100_bases
CAGTTTTAACAAAAAAACGCCACAGAAGCTCATATTTTATTTTTTTTAATAAATAATATCCCCCCATTAGTTTTGCTTAA
AAAAGCTGAAAAACGAATAT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFFMISLIIGLMSGISVVVAQYF
GFKDYDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLILLRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGN
SITPLIFLILSSLLNIALDFLFVVYMGMGVRGAAIATVLSQAGAAIAVIYYAYRHVPFMKIERSRFKLSTPLLKEMVRIG
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQNIGAGKLDRVREGFWSGIKVV
TVISIGITILVQLFARQFLLLFVDSSETEVINIGVSYLLIVSLFYVVVGILFVVRETLRGTGDAMVPLAMGIFELVSRLV
IGFVLSLYIGYVGLWWATPVAWITATMLGVWRYKSGTWQKKAVIRRK

Sequences:

>Translated_447_residues
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFFMISLIIGLMSGISVVVAQYF
GFKDYDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLILLRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGN
SITPLIFLILSSLLNIALDFLFVVYMGMGVRGAAIATVLSQAGAAIAVIYYAYRHVPFMKIERSRFKLSTPLLKEMVRIG
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQNIGAGKLDRVREGFWSGIKVV
TVISIGITILVQLFARQFLLLFVDSSETEVINIGVSYLLIVSLFYVVVGILFVVRETLRGTGDAMVPLAMGIFELVSRLV
IGFVLSLYIGYVGLWWATPVAWITATMLGVWRYKSGTWQKKAVIRRK
>Mature_447_residues
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFFMISLIIGLMSGISVVVAQYF
GFKDYDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLILLRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGN
SITPLIFLILSSLLNIALDFLFVVYMGMGVRGAAIATVLSQAGAAIAVIYYAYRHVPFMKIERSRFKLSTPLLKEMVRIG
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQNIGAGKLDRVREGFWSGIKVV
TVISIGITILVQLFARQFLLLFVDSSETEVINIGVSYLLIVSLFYVVVGILFVVRETLRGTGDAMVPLAMGIFELVSRLV
IGFVLSLYIGYVGLWWATPVAWITATMLGVWRYKSGTWQKKAVIRRK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=423, Percent_Identity=25.7683215130024, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48510; Mature: 48510

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MISLIIGLMSGISVVVAQYFGFKDYDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGNSITPLIFLILSSLLNIALDF
HCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LFVVYMGMGVRGAAIATVLSQAGAAIAVIYYAYRHVPFMKIERSRFKLSTPLLKEMVRIG
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHC
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQN
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
IGAGKLDRVREGFWSGIKVVTVISIGITILVQLFARQFLLLFVDSSETEVINIGVSYLLI
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHH
VSLFYVVVGILFVVRETLRGTGDAMVPLAMGIFELVSRLVIGFVLSLYIGYVGLWWATPV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWITATMLGVWRYKSGTWQKKAVIRRK
HHHHHHHHHHHHCCCCCCHHHHHHCCC
>Mature Secondary Structure
MMKDMTTGNPTKLIFLFAMPMLIGNLFQQFYTMIDAVIVGKFVSVDALAAVGATNSVNFF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MISLIIGLMSGISVVVAQYFGFKDYDRLKDVIATATYAVVFSAIILTVAGVLLAKPLLIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRTPANILDDSTIFLTTLFIGILPMSLYNGMAAILRALGNSITPLIFLILSSLLNIALDF
HCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LFVVYMGMGVRGAAIATVLSQAGAAIAVIYYAYRHVPFMKIERSRFKLSTPLLKEMVRIG
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHC
LPSGLQGSFISIGNMALQSLINGFGSSVVAAYTAASRIDSLTYQPGIAFGAASSMFAGQN
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
IGAGKLDRVREGFWSGIKVVTVISIGITILVQLFARQFLLLFVDSSETEVINIGVSYLLI
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHH
VSLFYVVVGILFVVRETLRGTGDAMVPLAMGIFELVSRLVIGFVLSLYIGYVGLWWATPV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWITATMLGVWRYKSGTWQKKAVIRRK
HHHHHHHHHHHHCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]