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The map label for this gene is mrdB [H]

Identifier: 116691132

GI number: 116691132

Start: 3429253

End: 3430401

Strand: Direct

Name: mrdB [H]

Synonym: Bcen2424_3114

Alternate gene names: 116691132

Gene position: 3429253-3430401 (Clockwise)

Preceding gene: 116691131

Following gene: 116691146

Centisome position: 98.43

GC content: 65.62

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTGGCTCGACAAGATCAAGCAGATGTTCGCGGGCTTCGATCGCCCGCTCGCCCTCATCGT
GTTCCTGCTGCTGTGCGTCGGCATCGTCACGCTGTACAGCGCGTCGATCGACATGCCGGGCCGCGTCGAGGACCAGTTGC
GCAACATCCTGCTGACGTTCGTGCTGATGTGGGTGATCGCCAACATCCCGCCGACCACGCTGATGCGCTTCGCGGTCCCG
CTCTACACGTTCGGGGTGACGCTGCTGATTGCGGTCGCGCTGTTCGGGATGACCAAGAAGGGCGCGAAGCGCTGGCTGAA
CGTCGGCGTCGTGATCCAGCCGTCCGAAATCCTCAAGATCGCGACGCCGCTGATGCTCGCGTGGTACTACCAGCGCCGCG
AAGGCGGGCTGCGCTGGTACGACTTCATCGCCGCGTTCGGAATCCTGCTGGTGCCGGTCGGGCTGATCGCGAAGCAGCCC
GACCTCGGCACGGGTCTGCTCGTGTTCGCGGCCGGCTTCTTCGTGATCTACCTCGCCGGCCTGTCGTTCAAGCTGATCGT
GCCGGTGCTCGTCGCGGGCGTGCTCGCGGTCGGCTCGATCGCCGTGTTCGAGGAACGCATCTGCCAGCCCGAAGTACAGT
GGCCGCTGATGCACGACTACCAGAAACACCGGGTGTGCACGCTGCTCGACCCGACCTCCGACCCACTCGGCAAGGGCTTC
CACACGATCCAGGCCGTGATCGCGATCGGCTCGGGCGGCGTGCTCGGCAAGGGCTACCTGAAAGGCACGCAGGCGCACCT
CGAATTCATTCCGGAAAAGCACACCGACTTCATCTTCGCGGTGTTCTCGGAGGAATGGGGGCTCGCCGGCGGGCTGGTGC
TGCTGACGCTGTACATGGCGCTGATCGCTCGCGGGCTCTACATCGCCGCGCAGGGCGCGACGCTGTTCGGCCGGCTGCTG
GCGGGCTCGCTCACGCTCGCGTTCTTCGTCTACGCGTTCGTCAACATCGGGATGGTGAGCGGCGTGCTGCCGGTCGTCGG
CGTGCCGTTGCCGTTCATGAGCTACGGCGGTACCGCGCTCACGACGCTCGGCATCGCGATCGGGATGATCATGAGCGTCG
GGCGGCAGCGGCGGCTGATGAAGAGCTGA

Upstream 100 bases:

>100_bases
ACGCGCAGCCGGTCGCCGCCGCGCCGCGGGACGACAACCATCGTGCGACGGCCCCCGCGAAAGCGGCGGACGCCGGCACC
GCTCATTAACGGAGAAAGGC

Downstream 100 bases:

>100_bases
TCGCGGCCCCGCACCGCGGCACACGAAAACGGCGCCCCGGCGCCGTTTTTCATTGGATGCGCCGAATGCGGCCGCCTACT
GCGGCGGCGCGTGCGGCTTG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVTLLIAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVLAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS

Sequences:

>Translated_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVTLLIAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVLAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS
>Mature_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVTLLIAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQP
DLGTGLLVFAAGFFVIYLAGLSFKLIVPVLVAGVLAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAIGMIMSVGRQRRLMKS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=380, Percent_Identity=48.6842105263158, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=30.1587301587302, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41752; Mature: 41752

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVTLLIAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQPDLGTGLLVFAAGFFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LSFKLIVPVLVAGVLAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVTLLIAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGLRWYDFIAAFGILLVPVGLIAKQPDLGTGLLVFAAGFFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LSFKLIVPVLVAGVLAVGSIAVFEERICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGVLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]